APRAGLUTIDE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Investigational

Investigational

Approval Year

Substance Class	Protein Created by `admin` on `Tue Apr 01 22:00:33 GMT 2025` Edited by `admin` on `Tue Apr 01 22:00:33 GMT 2025`
Protein Type	PEPTIDE
Protein Sub Type
Record UNII	CVQ1IAY2G6
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

Apraglutide [WHO-DD]

Preferred Name

English

APRAGLUTIDE

Official Name

English

L-?-Asparagine, L-histidylglycyl-L-?-aspartylglycyl-L-seryl-L-phenylalanyl-L-seryl-L-?-aspartyl-L-?-glutamyl-L-norleucyl-D-phenylalanyl-L-threonyl-L-isoleucyl-L-leucyl-L-?-aspartyl-L-leucyl-L-leucyl-L-alanyl-L-alanyl-L-arginyl-L-?-aspartyl-L-phenylalanyl

Systematic Name

English

apraglutide [INN]

Common Name

English

HIS-GLY-ASP-GLY-SER-PHE-SER-ASP-GLU-NLE-D-PHE-THR-ILE-LEU-ASP-LEU-LEU-ALA-ALA-ARG-ASP-PHE-ILE-ASN-TRP-LEU-ILE-GLN-THR-LYS-ILE-THR-ASP-NH2

Systematic Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

639518

Created by admin on Tue Apr 01 22:00:33 GMT 2025 , Edited by admin on Tue Apr 01 22:00:33 GMT 2025

FDA ORPHAN DRUG

817021

Created by admin on Tue Apr 01 22:00:33 GMT 2025 , Edited by admin on Tue Apr 01 22:00:33 GMT 2025

EU-Orphan Drug

EU/3/18/2102

Created by admin on Tue Apr 01 22:00:33 GMT 2025 , Edited by admin on Tue Apr 01 22:00:33 GMT 2025

Code System Code Type Description

INN

10705

Created by admin on Tue Apr 01 22:00:33 GMT 2025 , Edited by admin on Tue Apr 01 22:00:33 GMT 2025

PRIMARY

NCI_THESAURUS

C171811

Created by admin on Tue Apr 01 22:00:33 GMT 2025 , Edited by admin on Tue Apr 01 22:00:33 GMT 2025

PRIMARY

SMS_ID

100000177554

Created by admin on Tue Apr 01 22:00:33 GMT 2025 , Edited by admin on Tue Apr 01 22:00:33 GMT 2025

PRIMARY

FDA UNII

CVQ1IAY2G6

Created by admin on Tue Apr 01 22:00:33 GMT 2025 , Edited by admin on Tue Apr 01 22:00:33 GMT 2025

PRIMARY

CAS

1295353-98-8

Created by admin on Tue Apr 01 22:00:33 GMT 2025 , Edited by admin on Tue Apr 01 22:00:33 GMT 2025

PRIMARY

Related Record Type Details


					I22705MV2H

GLUCAGON-LIKE PEPTIDE 2 RECEPTOR

TARGET -> AGONIST

Amount:

Related Record Type Details


					CVQ1IAY2G6

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION	[1_10]				NORLEUCINE	832C8OV84S
AMINO_ACID_SUBSTITUTION	[1_33]				Isoasparagine	L9ANT46A26

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL