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Details

Stereochemistry ACHIRAL
Molecular Formula CH2ClF
Molecular Weight 68.478
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CHLOROFLUOROMETHANE

SMILES

FCCl

InChI

InChIKey=XWCDCDSDNJVCLO-UHFFFAOYSA-N
InChI=1S/CH2ClF/c2-1-3/h1H2

HIDE SMILES / InChI

Molecular Formula CH2ClF
Molecular Weight 68.478
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Beclometasone dipropionate extrafine aerosol versus fluticasone propionate in children with asthma.
2007-07
Changes in tropospheric composition and air quality due to stratospheric ozone depletion and climate change.
2007-03
1-BP inhibits NF-kappaB activity and Bcl-xL expression in astrocytes in vitro and reduces Bcl-xL expression in the brains of rats in vivo.
2007-03
Advances in asthma and COPD management: delivering CFC-free inhaled therapy using Modulite technology.
2007
Improved outcomes in patients with chronic obstructive pulmonary disease treated with salmeterol compared with placebo/usual therapy: results of a meta-analysis.
2006-12-29
Tunneling motions of argon on chlorofluoromethane.
2006-11-21
Effect of heliox on albuterol delivery by metered-dose inhaler in pediatric in vitro models of mechanical ventilation.
2006-10
Significance of the oceanic CO2 sink for national carbon accounts.
2006-07-21
Seasonal variability and long term trends of chlorofluorocarbon mixing ratios in the unsaturated zone.
2006-07-15
Clinical comparability between the CFC and HFA budesonide pressurised metered-dose inhalers in paediatric patients with asthma: a randomised controlled trial.
2006-06
Efficacy and safety of inhaled fluticasone propionate chlorofluorocarbon in 2- to 4-year-old patients with asthma: results of a double-blind, placebo-controlled study.
2006-06
Stratospheric ozone depletion.
2006-05-29
[Determination of chlorofluorocarbon residue in tobacco products by gas chromatography-electron capture detection].
2006-01
Efficacy and tolerability of fluticasone propionate/salmeterol administered twice daily via hydrofluoroalkane 134a metered-dose inhaler in adolescent and adult patients with persistent asthma: a randomized, double-blind, placebo-controlled, 12-week study.
2006-01
Fluticasone propionate hydrofluoroalkane inhalation aerosol in patients receiving inhaled corticosteroids.
2006-01
Beclometasone dipropionate/formoterol: in an HFA-propelled pressurised metered-dose inhaler.
2006
Metered-dose inhalers and dry powder inhalers in aerosol therapy.
2005-10
Reductive dechlorination of chlorofluorocarbons and hydrochlorofluorocarbons in sewage sludge and aquifer sediment microcosms.
2005-10
History of aerosol therapy: liquid nebulization to MDIs to DPIs.
2005-09
Low incidence of paradoxical bronchoconstriction in asthma and COPD patients during chronic use of Respimat soft mist inhaler.
2005-09
The effect of reducing the fine-particle mass of salmeterol from metered-dose inhalers on bronchodilatation and bronchoprotection against methacholine challenge: a randomized, placebo-controlled, double-blind, crossover study.
2005-07
Effects of mometasone furoate dry powder inhaler and beclomethasone dipropionate hydrofluoroalkane and chlorofluorocarbon on the hypothalamic-pituitary-adrenal axis in asthmatic subjects.
2005-07
Effects of HFA- and CFC-beclomethasone dipropionate on the bronchial response to methacholine (MCh) in mild asthma.
2005-07
Aerosolized liposome-based delivery of amphotericin B to alveolar macrophages.
2005-05-30
Surfactant solubility and aggregate orientation in hydrofluoroalkanes.
2005-05-13
Influence of ancient thrust faults on the hydrogeology of the Blue Ridge Province.
2005-05-11
Monitoring the initial pulmonary absorption of two different beclomethasone dipropionate aerosols employing a human lung reperfusion model.
2005-02-24
Inhaled beclomethasone versus placebo for chronic asthma.
2005-01-25
Comparison of the aerosol velocity and spray duration of Respimat Soft Mist inhaler and pressurized metered dose inhalers.
2005
Acute inhalational exposure to chlorodifluoromethane (freon-22): a report of 43 cases.
2005
Ipratropium bromide HFA.
2005
[Hydrofluoroalkane as a propellant for pressurized metered-dose inhalers: history, pulmonary deposition, pharmacokinetics, efficacy and safety].
2004-12-29
A novel formulation technique for metered dose inhaler (MDI) suspensions.
2004-10-13
How do patients determine that their metered-dose inhaler is empty?
2004-10
Guidelines versus clinical practice--which therapy and which device?
2004-10
Comparison of bronchoprotective and bronchodilator effects of a single dose of formoterol delivered by hydrofluoroalkane and chlorofluorocarbon aerosols and dry powder in a double blind, placebo-controlled, crossover study.
2004-10
Perfluoro-n-butyl iodide: acute toxicity, subchronic toxicity and genotoxicity evaluations.
2004-09-17
Impact of anthropogenic CO2 on the CaCO3 system in the oceans.
2004-07-16
The efficacy and safety of QVAR (hydrofluoroalkane-beclometasone diproprionate extrafine aerosol) in asthma (part 1): an update of clinical experience in adults.
2004-07
Flunisolide HFA for the treatment of asthma: an old friend reformulated.
2004-05
Once-daily budesonide aqueous nasal spray for allergic rhinitis: a review.
2004-04
Safety and efficacy of HFA-134a beclomethasone dipropionate extra-fine aerosol over six months.
2004-03
Efficacy and safety of ipratropium bromide plus fenoterol inhaled via Respimat Soft Mist Inhaler vs. a conventional metered dose inhaler plus spacer in children with asthma.
2004-03
Evaluation of the Malvern Spraytec with inhalation cell for the measurement of particle size distribution from metered dose inhalers.
2004-02
Design of liposomal aerosols for improved delivery of rifampicin to alveolar macrophages.
2004-01-09
A review of ipratropium bromide/fenoterol hydrobromide (Berodual) delivered via Respimat Soft Mist Inhaler in patients with asthma and chronic obstructive pulmonary disease.
2004
Hydrofluoroalkane formulations of inhaled corticosteroids for the treatment of asthma.
2004
The delivery of chlorofluorocarbon-propelled versus hydrofluoroalkane-propelled beclomethasone dipropionate aerosol to the mechanically ventilated patient: a laboratory study.
2003-11
Clinical efficacy of inhaler devices containing beta(2)-agonist bronchodilators in the treatment of asthma: cochrane systematic review and meta-analysis of more than 100 randomized, controlled trials.
2003
Inhaled steroids: are they all created equal?
2002-08
Substance Class Chemical
Created
by admin
on Mon Mar 31 19:28:17 GMT 2025
Edited
by admin
on Mon Mar 31 19:28:17 GMT 2025
Record UNII
CUM8OUO53E
Record Status Validated (UNII)
Record Version
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Name Type Language
CHLOROFLUOROMETHANE
Systematic Name English
CFC 31
Preferred Name English
FLUOROCHLOROMETHANE
Systematic Name English
CHLOROFLUOROMETHANE [IARC]
Common Name English
R31
Code English
FREON 31
Common Name English
R-31
Code English
Classification Tree Code System Code
CFR 21 CFR 189.191
Created by admin on Mon Mar 31 19:28:17 GMT 2025 , Edited by admin on Mon Mar 31 19:28:17 GMT 2025
Code System Code Type Description
EPA CompTox
DTXSID6020305
Created by admin on Mon Mar 31 19:28:17 GMT 2025 , Edited by admin on Mon Mar 31 19:28:17 GMT 2025
PRIMARY
CAS
593-70-4
Created by admin on Mon Mar 31 19:28:17 GMT 2025 , Edited by admin on Mon Mar 31 19:28:17 GMT 2025
PRIMARY
MESH
C039310
Created by admin on Mon Mar 31 19:28:17 GMT 2025 , Edited by admin on Mon Mar 31 19:28:17 GMT 2025
PRIMARY
WIKIPEDIA
CHLOROFLUOROMETHANE
Created by admin on Mon Mar 31 19:28:17 GMT 2025 , Edited by admin on Mon Mar 31 19:28:17 GMT 2025
PRIMARY
ECHA (EC/EINECS)
209-803-2
Created by admin on Mon Mar 31 19:28:17 GMT 2025 , Edited by admin on Mon Mar 31 19:28:17 GMT 2025
PRIMARY
PUBCHEM
11643
Created by admin on Mon Mar 31 19:28:17 GMT 2025 , Edited by admin on Mon Mar 31 19:28:17 GMT 2025
PRIMARY
FDA UNII
CUM8OUO53E
Created by admin on Mon Mar 31 19:28:17 GMT 2025 , Edited by admin on Mon Mar 31 19:28:17 GMT 2025
PRIMARY