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Details

Stereochemistry ABSOLUTE
Molecular Formula C9H11N2O12P2.2Na.H
Molecular Weight 448.1248
Optical Activity UNSPECIFIED
Defined Stereocenters 4 / 4
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DISODIUM URIDINE 5'-DIPHOSPHATE

SMILES

[H+].[Na+].[Na+].O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP([O-])(=O)OP([O-])([O-])=O)N2C=CC(=O)NC2=O

InChI

InChIKey=ZQKVPFKBNNAXCE-WFIJOQBCSA-L
InChI=1S/C9H14N2O12P2.2Na/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(22-8)3-21-25(19,20)23-24(16,17)18;;/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,10,12,15)(H2,16,17,18);;/q;2*+1/p-2/t4-,6-,7-,8-;;/m1../s1

HIDE SMILES / InChI

Molecular Formula Na
Molecular Weight 22.9898
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C9H11N2O12P2
Molecular Weight 401.1374
Charge -3
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 4 / 4
E/Z Centers 0
Optical Activity UNSPECIFIED

Molecular Formula H
Molecular Weight 1.0079
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Intact Golgi synthesize complex branched O-linked chains on glycoside primers: evidence for the functional continuity of seven glycosyltransferases and three sugar nucleotide transporters.
2001 Aug
Galactose-1-phosphate uridylyltransferase: kinetics of formation and reaction of uridylyl-enzyme intermediate in wild-type and specifically mutated uridylyltransferases.
2002
Effect of a conserved mutation in uridine diphosphate glucuronosyltransferase 1A1 and 1A6 on glucuronidation of a metabolite of flutamide.
2002 Apr
P2Y receptor-induced EDHF vasodilatation is of primary importance for the regulation of perfusion pressure in the peripheral circulation of the rat.
2002 Apr
Fast, efficient capillary electrophoresis method for measuring nucleotide degradation and metabolism.
2002 Apr 5
Nucleotide receptors involved in UTP-induced rat arterial smooth muscle cell migration.
2002 Apr 5
Significance of altered bilirubin subfractions in bile following hepatectomy.
2002 Jul
Accumulation of the lipid A precursor UDP-2,3-diacylglucosamine in an Escherichia coli mutant lacking the lpxH gene.
2002 Jul 19
Evaluation of critical structural elements of UDP-sugar substrates and certain cysteine residues of a vertebrate hyaluronan synthase.
2002 Jun 14
A sensitive and rapid bioassay of homogalacturonan synthase using 2-aminobenzamide-labeled oligogalacturonides.
2002 Nov
Muscle uridine diphosphate-hexosamines do not decrease despite correction of hyperglycemia-induced insulin resistance in type 2 diabetes.
2002 Nov
Metabolizing enzyme localization and activities in the first trimester human placenta: the effect of maternal and gestational age, smoking and alcohol consumption.
2002 Oct
Analgesic effects of intrathecal administration of P2Y nucleotide receptor agonists UTP and UDP in normal and neuropathic pain model rats.
2002 Oct
Arabinoxylan biosynthesis in wheat. Characterization of arabinosyltransferase activity in Golgi membranes.
2002 Sep
Identification of two cysteine residues involved in the binding of UDP-GalNAc to UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1).
2002 Sep
The structural basis for specificity in human ABO(H) blood group biosynthesis.
2002 Sep
The Drosophila gene brainiac encodes a glycosyltransferase putatively involved in glycosphingolipid synthesis.
2002 Sep 6
Pharmacological characterization of P2Y receptor subtypes on isolated tiger salamander Müller cells.
2003 Apr 15
Coexpression of functional P2X and P2Y nucleotide receptors in single cerebellar granule cells.
2003 Aug 1
The role of tryptophan 314 in the conformational changes of beta1,4-galactosyltransferase-I.
2003 Aug 29
Chondroitin sulfate synthase-2. Molecular cloning and characterization of a novel human glycosyltransferase homologous to chondroitin sulfate glucuronyltransferase, which has dual enzymatic activities.
2003 Aug 8
Glucosamine and glucose induce insulin resistance by different mechanisms in rat skeletal muscle.
2003 Dec
A novel polygalacturonic acid bioflocculant REA-11 produced by Corynebacterium glutamicum: a proposed biosynthetic pathway and experimental confirmation.
2003 Dec
Age-related changes in the response of human articular cartilage to IL-1alpha and transforming growth factor-beta (TGF-beta): chondrocytes exhibit a diminished sensitivity to TGF-beta.
2003 Dec 26
Normally functioning murF is essential for the optimal expression of methicillin resistance in Staphylococcus aureus.
2003 Fall
Long-term potentiation of glutamatergic synaptic transmission induced by activation of presynaptic P2Y receptors in the rat medial habenula nucleus.
2003 Feb
Altered calcium regulation in freshly isolated aortic smooth muscle cells from bile duct-ligated rats: role of nitric oxide.
2003 Feb
Pyridoxalphosphate-6-azophenyl-2',4'-disulfonic acid can antagonize the purinoceptor-mediated inhibition of M-current in bullfrog sympathetic neurons.
2003 Feb 6
Three highly conserved proteins catalyze the conversion of UDP-N-acetyl-D-glucosamine to precursors for the biosynthesis of O antigen in Pseudomonas aeruginosa O11 and capsule in Staphylococcus aureus type 5. Implications for the UDP-N-acetyl-L-fucosamine biosynthetic pathway.
2003 Feb 7
Mast cells: beyond IgE.
2003 Jan
The stable pyrimidines UDPbetaS and UTPgammaS discriminate between contractile cerebrovascular P2 receptors.
2003 Jan 5
Probing the mechanism of a fungal glycosyltransferase essential for cell wall biosynthesis. UDP-chitobiose is not a substrate for chitin synthase.
2003 Jan 7
Chemical synthesis of uridine diphospho-D-xylose and UDP-L-arabinose.
2003 Jul 11
Crystal structures of the T4 phage beta-glucosyltransferase and the D100A mutant in complex with UDP-glucose: glucose binding and identification of the catalytic base for a direct displacement mechanism.
2003 Jul 25
P2Y6 nucleotide receptor activates PKC to protect 1321N1 astrocytoma cells against tumor necrosis factor-induced apoptosis.
2003 Jun
Purinergic receptors on microglial cells: functional expression in acute brain slices and modulation of microglial activation in vitro.
2003 Jun
A high-throughput solid-phase extraction assay capable of measuring diverse polyprenyl phosphate: sugar-1-phosphate transferases as exemplified by the WecA, MraY, and MurG proteins.
2003 Jun 15
The folate precursor p-aminobenzoate is reversibly converted to its glucose ester in the plant cytosol.
2003 Jun 6
[Pharmacogenomic approaches for prevention of drug toxicity in cancer chemotherapy].
2003 Mar
ATP-induced calcium oscillations and change of P2Y subtypes with culture conditions in HeLa cells.
2003 Mar
Beta 1,4-galactosyltransferase (beta 4GalT)-IV is specific for GlcNAc 6-O-sulfate. Beta 4GalT-IV acts on keratan sulfate-related glycans and a precursor glycan of 6-sulfosialyl-Lewis X.
2003 Mar 14
Measurement of UDP-N-acetylglucosaminyl transferase (OGT) in brain cytosol and characterization of anti-OGT antibodies.
2003 Mar 15
Tumor necrosis factor alpha-induced apoptosis in astrocytes is prevented by the activation of P2Y6, but not P2Y4 nucleotide receptors.
2003 Mar 15
Potent P2Y6 receptor mediated contractions in human cerebral arteries.
2003 May 9
Diabetes and the accompanying hyperglycemia impairs cardiomyocyte calcium cycling through increased nuclear O-GlcNAcylation.
2003 Nov 7
Analysis of the two active sites of the hyaluronan synthase and the chondroitin synthase of Pasteurella multocida.
2003 Oct
In vitro heparan sulfate polymerization: crucial roles of core protein moieties of primer substrates in addition to the EXT1-EXT2 interaction.
2003 Oct 24
Extracellular nucleotides and nucleosides induce proliferation and increase nucleoside transport in human glioma cell lines.
2003 Sep
UDP-N-acetylglucosaminyl transferase (OGT) in brain tissue: temperature sensitivity and subcellular distribution of cytosolic and nuclear enzyme.
2003 Sep
Solid-supported enzymatic synthesis of pectic oligogalacturonides and their analysis by MALDI-TOF mass spectrometry.
2003 Sep 10
Substance Class Chemical
Created
by admin
on Sat Dec 16 09:41:30 GMT 2023
Edited
by admin
on Sat Dec 16 09:41:30 GMT 2023
Record UNII
CU84BH96WL
Record Status Validated (UNII)
Record Version
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Name Type Language
DISODIUM URIDINE 5'-DIPHOSPHATE
Systematic Name English
UDP DISODIUM SALT
Common Name English
Uridine diphosphate disodium [WHO-DD]
Common Name English
URIDINE-5'-DIPHOSPHATE DISODIUM SALT
Common Name English
URIDINE 5'-(TRIHYDROGEN DIPHOSPHATE), SODIUM SALT (1:2)
Common Name English
Code System Code Type Description
CAS
27821-45-0
Created by admin on Sat Dec 16 09:41:30 GMT 2023 , Edited by admin on Sat Dec 16 09:41:30 GMT 2023
PRIMARY
PUBCHEM
11957711
Created by admin on Sat Dec 16 09:41:30 GMT 2023 , Edited by admin on Sat Dec 16 09:41:30 GMT 2023
PRIMARY
EVMPD
SUB170479
Created by admin on Sat Dec 16 09:41:30 GMT 2023 , Edited by admin on Sat Dec 16 09:41:30 GMT 2023
PRIMARY
SMS_ID
100000159729
Created by admin on Sat Dec 16 09:41:30 GMT 2023 , Edited by admin on Sat Dec 16 09:41:30 GMT 2023
PRIMARY
FDA UNII
CU84BH96WL
Created by admin on Sat Dec 16 09:41:30 GMT 2023 , Edited by admin on Sat Dec 16 09:41:30 GMT 2023
PRIMARY
Related Record Type Details
SOLVATE->ANHYDROUS