BRIFENTANIL HYDROCHLORIDE

Details

Stereochemistry	RACEMIC
Molecular Formula	C20H29FN6O3.ClH
Molecular Weight	456.942
Optical Activity	( + / - )
Defined Stereocenters	2 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cl.CCN1N=NN(CCN2CC[C@H]([C@@H](C)C2)N(C(=O)COC)C3=C(F)C=CC=C3)C1=O

InChI

InChIKey=VHXNDLUDRKRBCQ-KPVRICSOSA-N

InChI=1S/C20H29FN6O3.ClH/c1-4-25-20(29)26(23-22-25)12-11-24-10-9-17(15(2)13-24)27(19(28)14-30-3)18-8-6-5-7-16(18)21;/h5-8,15,17H,4,9-14H2,1-3H3;1H/t15-,17+;/m0./s1

HIDE SMILES / InChI

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C20H29FN6O3
Molecular Weight	420.4811
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/1874883 | https://www.ncbi.nlm.nih.gov/pubmed/1798508 | https://www.ncbi.nlm.nih.gov/pubmed/2170652 | https://www.drugbank.ca/drugs/DB09172

Brifentanii, a potent narcotic analgesic structurally similar to alfentanil, that was studied in clinical trials in the early 1990s. The effects of brifentanil are very similar to those of alfentanil, with strong but short lasting analgesia and sedation, and particularly notable itching and respiratory depression. Side effects of Brifentanii are similar to those of fentanyl itself, which include itching, nausea and potentially serious respiratory depression, which can be life-threatening.

Originator

Approval Year

Patents

Substance Class	Chemical Created by `admin` on `Sat Dec 16 05:42:42 UTC 2023` Edited by `admin` on `Sat Dec 16 05:42:42 UTC 2023`
Record UNII	CT60LNZ8I8
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

BRIFENTANIL HYDROCHLORIDE

Official Name

English

ACETAMIDE, N-(1-(2-(4-ETHYL-4,5-DIHYDRO-5-OXO-1H-TETRAZOL-1-YL)ETHYL)-3-METHYL-4-PIPERIDINYL)-N-(2-FLUOROPHENYL)-2-METHOXY-, MONOHYDROCHLORIDE, CIS-(±)-

Common Name

English

(±)-CIS-N-(1-(2-(4-ETHYL-5-OXO-2-TETRAZOLIN-1-YL)ETHYL)-3-METHYL-4-PIPERIDYL)-2'-FLUORO-2-METHOXYACETANILIDE MONOHYDROCHLORIDE

Systematic Name

English

Brifentanil hydrochloride [WHO-DD]

Common Name

English

BRIFENTANIL HYDROCHLORIDE [USAN]

Common Name

English

A-3331

Code

English

A 3331

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C241