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Details

Stereochemistry RACEMIC
Molecular Formula C20H29FN6O3.ClH
Molecular Weight 456.942
Optical Activity ( + / - )
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of BRIFENTANIL HYDROCHLORIDE

SMILES

Cl.CCN1N=NN(CCN2CC[C@H]([C@@H](C)C2)N(C(=O)COC)C3=C(F)C=CC=C3)C1=O

InChI

InChIKey=VHXNDLUDRKRBCQ-KPVRICSOSA-N
InChI=1S/C20H29FN6O3.ClH/c1-4-25-20(29)26(23-22-25)12-11-24-10-9-17(15(2)13-24)27(19(28)14-30-3)18-8-6-5-7-16(18)21;/h5-8,15,17H,4,9-14H2,1-3H3;1H/t15-,17+;/m0./s1

HIDE SMILES / InChI

Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C20H29FN6O3
Molecular Weight 420.4811
Charge 0
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 2 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED

Brifentanii, a potent narcotic analgesic structurally similar to alfentanil, that was studied in clinical trials in the early 1990s. The effects of brifentanil are very similar to those of alfentanil, with strong but short lasting analgesia and sedation, and particularly notable itching and respiratory depression. Side effects of Brifentanii are similar to those of fentanyl itself, which include itching, nausea and potentially serious respiratory depression, which can be life-threatening.

Approval Year

Substance Class Chemical
Created
by admin
on Sat Dec 16 05:42:42 GMT 2023
Edited
by admin
on Sat Dec 16 05:42:42 GMT 2023
Record UNII
CT60LNZ8I8
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
BRIFENTANIL HYDROCHLORIDE
USAN   WHO-DD  
USAN  
Official Name English
ACETAMIDE, N-(1-(2-(4-ETHYL-4,5-DIHYDRO-5-OXO-1H-TETRAZOL-1-YL)ETHYL)-3-METHYL-4-PIPERIDINYL)-N-(2-FLUOROPHENYL)-2-METHOXY-, MONOHYDROCHLORIDE, CIS-(±)-
Common Name English
(±)-CIS-N-(1-(2-(4-ETHYL-5-OXO-2-TETRAZOLIN-1-YL)ETHYL)-3-METHYL-4-PIPERIDYL)-2'-FLUORO-2-METHOXYACETANILIDE MONOHYDROCHLORIDE
Systematic Name English
Brifentanil hydrochloride [WHO-DD]
Common Name English
BRIFENTANIL HYDROCHLORIDE [USAN]
Common Name English
A-3331
Code English
A 3331
Code English
Classification Tree Code System Code
NCI_THESAURUS C241
Created by admin on Sat Dec 16 05:42:42 GMT 2023 , Edited by admin on Sat Dec 16 05:42:42 GMT 2023
Code System Code Type Description
NCI_THESAURUS
C96944
Created by admin on Sat Dec 16 05:42:42 GMT 2023 , Edited by admin on Sat Dec 16 05:42:42 GMT 2023
PRIMARY
PUBCHEM
46174071
Created by admin on Sat Dec 16 05:42:42 GMT 2023 , Edited by admin on Sat Dec 16 05:42:42 GMT 2023
PRIMARY
EPA CompTox
DTXSID70922381
Created by admin on Sat Dec 16 05:42:42 GMT 2023 , Edited by admin on Sat Dec 16 05:42:42 GMT 2023
PRIMARY
FDA UNII
CT60LNZ8I8
Created by admin on Sat Dec 16 05:42:42 GMT 2023 , Edited by admin on Sat Dec 16 05:42:42 GMT 2023
PRIMARY
ChEMBL
CHEMBL2220476
Created by admin on Sat Dec 16 05:42:42 GMT 2023 , Edited by admin on Sat Dec 16 05:42:42 GMT 2023
PRIMARY
USAN
BB-16
Created by admin on Sat Dec 16 05:42:42 GMT 2023 , Edited by admin on Sat Dec 16 05:42:42 GMT 2023
PRIMARY
CAS
117268-95-8
Created by admin on Sat Dec 16 05:42:42 GMT 2023 , Edited by admin on Sat Dec 16 05:42:42 GMT 2023
PRIMARY
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