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Approval Year

Substance Class Structurally Diverse
Created
by admin
on Sat Dec 16 18:45:59 UTC 2023
Edited
by admin
on Sat Dec 16 18:45:59 UTC 2023
Source Materials Class ORGANISM
Source Materials Type ALLOGENIC HUMAN
Source Materials Parent
Part BLOOD
Fraction Name CD34+ enriched Hematopoietic Stem/Progenitor Cell from HLA matched donor
Record UNII
CT5FM8JN3S
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
Tremtelectogene Empogeditemcel
Code English
allogeneic human CD34 + hematopoietic stem and progenitor cells (HSPC) obtained from peripheral blood by leukapheresis from human leukocyte antigen (HLA)-matched healthy donors, genetically modified ex vivo by CRISPR/Cas9 (clustered regularly interspaced
Common Name English
tremtelectogene empogeditemcel [INN]
Common Name English
Code System Code Type Description
INN
12263
Created by admin on Sat Dec 16 18:45:59 UTC 2023 , Edited by admin on Sat Dec 16 18:45:59 UTC 2023
PRIMARY
FDA UNII
CT5FM8JN3S
Created by admin on Sat Dec 16 18:45:59 UTC 2023 , Edited by admin on Sat Dec 16 18:45:59 UTC 2023
PRIMARY
NCI_THESAURUS
C180524
Created by admin on Sat Dec 16 18:45:59 UTC 2023 , Edited by admin on Sat Dec 16 18:45:59 UTC 2023
PRIMARY
Related Record Type Details
ACTIVE MOIETY
VOR33 will be infused into patients with acute myeloid leukemia (AML) undergoing hematopoietic cell transplant who are known to be at high-risk for leukemia relapse and mortality post transplantation.