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Details

Stereochemistry ACHIRAL
Molecular Formula C17H14O6
Molecular Weight 314.2895
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of VELUTIN

SMILES

COC1=CC2=C(C(=O)C=C(O2)C3=CC(OC)=C(O)C=C3)C(O)=C1

InChI

InChIKey=ROCUOVBWAWAQFD-UHFFFAOYSA-N
InChI=1S/C17H14O6/c1-21-10-6-12(19)17-13(20)8-14(23-16(17)7-10)9-3-4-11(18)15(5-9)22-2/h3-8,18-19H,1-2H3

HIDE SMILES / InChI

Molecular Formula C17H14O6
Molecular Weight 314.2895
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Differential abilities of the mushroom ribosome-inactivating proteins hypsin and velutin to perturb normal development of cultured mouse embryos.
2010-06
A phenethyl bromo ester from Citharexylum fruticosum.
2010-03
Chemical constituents from tiger's betel, Piper porphyrophyllum N.E.Br. (Fam. Piperaceae).
2010-03
Trypsin isoinhibitors with antiproliferative activity toward leukemia cells from Phaseolus vulgaris cv "White Cloud Bean".
2010
Binding modes of two novel non-nucleoside reverse transcriptase inhibitors, YM-215389 and YM-228855, to HIV type-1 reverse transcriptase.
2008
Flavonoids from Daphne giraldii Nitsche.
2008
Iridoid glucosides and flavones from the aerial parts of Avicennia marina.
2006-07
Isolation of flavonoids, a biscoumarin and an amide from the flower buds of Daphne genkwa and the evaluation of their anti-complement activity.
2006-07
The pharmacological potential of mushrooms.
2005-09
Cytotoxic triterpenoids from Acridocarpus vivy from the Madagascar rain forest.
2004-06
Ent-pimarane type diterpenes from Gnaphalium gaudichaudianum.
2003-02
Isolation of pleuturegin, a novel ribosome-inactivating protein from fresh sclerotia of the edible mushroom Pleurotus tuber-regium.
2001-11-02
Isolation and characterization of velutin, a novel low-molecular-weight ribosome-inactivating protein from winter mushroom (Flammulina velutipes) fruiting bodies.
2001-03-23
Evaluation of natural products as inhibitors of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase.
1991-01-01
Substance Class Chemical
Created
by admin
on Mon Mar 31 22:56:45 GMT 2025
Edited
by admin
on Mon Mar 31 22:56:45 GMT 2025
Record UNII
CT1Q4E0I0W
Record Status Validated (UNII)
Record Version
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Name Type Language
VELUTIN
INCI  
Official Name English
DR 9606128
Preferred Name English
4H-1-BENZOPYRAN-4-ONE, 5-HYDROXY-2-(4-HYDROXY-3-METHOXYPHENYL)-7-METHOXY-
Systematic Name English
FLAVOYADORIGENIN B
Common Name English
CHRYSOERIOL 7-METHYL ETHER
Common Name English
LUTEOLIN 3',7-DIMETHYL ETHER
Common Name English
FLAVONE, 4',5-DIHYDROXY-3',7-DIMETHOXY-
Systematic Name English
3',7-DIMETHYLLUTEOLIN
Common Name English
Code System Code Type Description
EPA CompTox
DTXSID90180421
Created by admin on Mon Mar 31 22:56:45 GMT 2025 , Edited by admin on Mon Mar 31 22:56:45 GMT 2025
PRIMARY
FDA UNII
CT1Q4E0I0W
Created by admin on Mon Mar 31 22:56:45 GMT 2025 , Edited by admin on Mon Mar 31 22:56:45 GMT 2025
PRIMARY
CAS
25739-41-7
Created by admin on Mon Mar 31 22:56:45 GMT 2025 , Edited by admin on Mon Mar 31 22:56:45 GMT 2025
PRIMARY
WIKIPEDIA
Velutin
Created by admin on Mon Mar 31 22:56:45 GMT 2025 , Edited by admin on Mon Mar 31 22:56:45 GMT 2025
PRIMARY
PUBCHEM
5464381
Created by admin on Mon Mar 31 22:56:45 GMT 2025 , Edited by admin on Mon Mar 31 22:56:45 GMT 2025
PRIMARY
Related Record Type Details
PARENT -> CONSTITUENT ALWAYS PRESENT
Velutin significantly inhibited p38 and JNK phosphorylation at 5 and 10 uM.The SEAP reporter assay was conducted to evaluate the inhibitory effects of velutin in inhibiting NF-.KAPPA.B activation in our previous report. The IC50 values of this compound was estimated at 2.0 uM for velutin.
PARENT -> CONSTITUENT ALWAYS PRESENT
ORAC value expressed as umol TE/g for this compound 13643.3 +/- 1119.5. ORAC is a chemical antioxidant assay that is based on the inhibition of the peroxyl-radical induced oxidation initiated by thermal decomposition of AAPH.