GARIVULIMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Investigational

Investigational

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 07:52:49 GMT 2025` Edited by `admin` on `Wed Apr 02 07:52:49 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type
Sequence Type	COMPLETE
Record UNII	CSJ7UEQ4D9
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

GARIVULIMAB

Official Name

English

garivulimab [INN]

Preferred Name

English

BGB-A333

Code

English

IMMUNOGLOBULIN G1 (233-PROLINE,234-ALANINE,235-ALANINE,DE-237-GLYCINE,329-ALANINE), ANTI-(HUMAN PROGRAMMED CELL DEATH LIGAND 1) (HUMAN-MUS MUSCULUS MONOCLONAL BGB-A333 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL BGB-A333 .KAPPA.-CHAIN,

Common Name

English

IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS CD274 (PROGRAMMED DEATH LIGAND 1, PDL1, PD-L1, B7 HOMOLOG 1, B7H1)), HUMANIZED MONOCLONAL ANTIBODY

Common Name

English

BGB A333

Code

English

Code System Code Type Description

CAS

2342597-81-1

Created by admin on Wed Apr 02 07:52:49 GMT 2025 , Edited by admin on Wed Apr 02 07:52:49 GMT 2025

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SMS_ID

300000028764

Created by admin on Wed Apr 02 07:52:49 GMT 2025 , Edited by admin on Wed Apr 02 07:52:49 GMT 2025

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NCI_THESAURUS

C155654

Created by admin on Wed Apr 02 07:52:49 GMT 2025 , Edited by admin on Wed Apr 02 07:52:49 GMT 2025

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FDA UNII

CSJ7UEQ4D9

Created by admin on Wed Apr 02 07:52:49 GMT 2025 , Edited by admin on Wed Apr 02 07:52:49 GMT 2025

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INN

11451

Created by admin on Wed Apr 02 07:52:49 GMT 2025 , Edited by admin on Wed Apr 02 07:52:49 GMT 2025

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From	To
4_135	4_195
4_23	4_88
3_135	3_195
3_23	3_88
2_366	2_424
2_260	2_320
2_220	4_215
1_220	3_215
2_144	2_200
2_22	2_95
1_366	1_424
1_260	1_320
1_229	2_229
1_226	2_226
1_144	1_200
1_22	1_95

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_296
N	2_296

Related Record Type Details


					L4766ELH5T

PROGRAMMED CELL DEATH 1 LIGAND 1

TARGET -> INHIBITOR

Amount:

Related Record Type Details


					CSJ7UEQ4D9

ACTIVE MOIETY

Comments:

Immunomodulator, antineoplastic

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID REMOVAL	[1_446] [2_446]	C-TERMINUS			LYSINE	K3Z4F929H6

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL