Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C12H10I3N2O4.Na |
| Molecular Weight | 649.922 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[Na+].CC(=O)NCC1=C(I)C(NC(C)=O)=C(I)C(C([O-])=O)=C1I
InChI
InChIKey=SJOULNBNMIRTRG-UHFFFAOYSA-M
InChI=1S/C12H11I3N2O4.Na/c1-4(18)16-3-6-8(13)7(12(20)21)10(15)11(9(6)14)17-5(2)19;/h3H2,1-2H3,(H,16,18)(H,17,19)(H,20,21);/q;+1/p-1
| Molecular Formula | C12H10I3N2O4 |
| Molecular Weight | 626.9322 |
| Charge | -1 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | Na |
| Molecular Weight | 22.98976928 |
| Charge | 1 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Iodamide is an ionic monomeric iodinated radiographic contrast medium. It was used in many procedures and may be given intravenously or by other routes, for example by instillation into the bladder or uterus; it has also been used for computed tomography. It is usually given as a 24 to 65% solution of the meglumine salt, or as a mixture of the sodium and meglumine salts; solutions of the sodium salt have also been used. Iodamide is no longer marketed in the US.
Approval Year
AUC
| Value | Dose | Co-administered | Analyte | Population |
|---|---|---|---|---|
2.58 g × h/L EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/338644 |
24.75 g single, intravenous dose: 24.75 g route of administration: Intravenous experiment type: SINGLE co-administered: |
IODAMIDE plasma | Homo sapiens population: HEALTHY age: ADULT sex: MALE food status: UNKNOWN |
|
6.69 g × h/L EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/338644 |
61.82 g single, intravenous dose: 61.82 g route of administration: Intravenous experiment type: SINGLE co-administered: |
IODAMIDE plasma | Homo sapiens population: HEALTHY age: ADULT sex: MALE food status: UNKNOWN |
|
14.02 g × h/L EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/338644 |
9.8 g single, intravenous dose: 9.8 g route of administration: Intravenous experiment type: SINGLE co-administered: |
IODAMIDE plasma | Homo sapiens population: UNHEALTHY age: ADULT sex: FEMALE / MALE food status: UNKNOWN |
T1/2
| Value | Dose | Co-administered | Analyte | Population |
|---|---|---|---|---|
1.29 h EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/338644 |
24.75 g single, intravenous dose: 24.75 g route of administration: Intravenous experiment type: SINGLE co-administered: |
IODAMIDE plasma | Homo sapiens population: HEALTHY age: ADULT sex: MALE food status: UNKNOWN |
|
1.02 h EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/338644 |
61.82 g single, intravenous dose: 61.82 g route of administration: Intravenous experiment type: SINGLE co-administered: |
IODAMIDE plasma | Homo sapiens population: HEALTHY age: ADULT sex: MALE food status: UNKNOWN |
|
16.4 h EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/338644 |
9.8 g single, intravenous dose: 9.8 g route of administration: Intravenous experiment type: SINGLE co-administered: |
IODAMIDE plasma | Homo sapiens population: UNHEALTHY age: ADULT sex: FEMALE / MALE food status: UNKNOWN |
Funbound
| Value | Dose | Co-administered | Analyte | Population |
|---|---|---|---|---|
95% EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/338644 |
24.75 g single, intravenous dose: 24.75 g route of administration: Intravenous experiment type: SINGLE co-administered: |
IODAMIDE plasma | Homo sapiens population: HEALTHY age: ADULT sex: MALE food status: UNKNOWN |
|
95% EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/338644 |
61.82 g single, intravenous dose: 61.82 g route of administration: Intravenous experiment type: SINGLE co-administered: |
IODAMIDE plasma | Homo sapiens population: HEALTHY age: ADULT sex: MALE food status: UNKNOWN |
PubMed
| Title | Date | PubMed |
|---|---|---|
| Diagnostic image quality of hysterosalpingography: ionic versus non ionic water soluble iodinated contrast media. | 2009-07 |
|
| Effects of iodinated contrast media on endothelium: An in vitro study. | 2007-03 |
|
| Contrast-enhanced voiding US for grading of reflux in adult patients prior to antireflux ureteral implantation. | 2004-10 |
|
| [The effect of diagnostic contrast media on the activity of lactate dehydrogenase in rat blood]. | 2002-11-27 |
|
| Comparative multiclinical studies of iodamide and diatrizoate in excretory urography. | 1973-01 |
| Substance Class |
Chemical
Created
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Edited
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| Record UNII |
CRK52426X3
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