TECHNETIUM TC-99M PENTETATE CALCIUM TRISODIUM

First approved in 1973

Details

Stereochemistry	ACHIRAL
Molecular Formula	C14H18N3O10.Ca.3Na.Tc
Molecular Weight	596.26
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of TECHNETIUM TC-99M PENTETATE CALCIUM TRISODIUM

Structure Search

SMILES

[Na+].[Na+].[Na+].[Ca++].[99Tc].[O-]C(=O)CN(CCN(CC([O-])=O)CC([O-])=O)CCN(CC([O-])=O)CC([O-])=O

InChI

InChIKey=QCEQOMIDBJVXLU-PUQAOBSFSA-I

InChI=1S/C14H23N3O10.Ca.3Na.Tc/c18-10(19)5-15(1-3-16(6-11(20)21)7-12(22)23)2-4-17(8-13(24)25)9-14(26)27;;;;;/h1-9H2,(H,18,19)(H,20,21)(H,22,23)(H,24,25)(H,26,27);;;;;/q;+2;3*+1;/p-5/i;;;;;1+1

HIDE SMILES / InChI

Molecular Formula	Na
Molecular Weight	22.9898
Charge	1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C14H18N3O10
Molecular Weight	388.3068
Charge	-5
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	Tc
Molecular Weight	98.9063
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	Ca
Molecular Weight	40.078
Charge	2
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.hindawi.com/journals/stni/2014/839369/
Curator's Comment: description was created based on several sources, including https://www.ncbi.nlm.nih.gov/books/NBK215133/ | https://www.iaea.org/OurWork/ST/NE/NEFW/Technical-Areas/RRS/documents /mo99/WORKINGMATERIALSmo99CM.pdf | https://www.ncbi.nlm.nih.gov/pubmed/27854401

Molybdenum-99 (99Mo, half-life = 66 h) is a parent radionuclide of a diagnostic nuclear isotope. It decays in technetium-99 m (half-life = 6 h), which is used in over 30 million procedures per year around the world. Between 95 and 98 percent of Mo-99 is currently being produced using highly enriched uranium (HEU) targets. Other medical isotopes such as iodine-131 (I-131) and xenon-133 (Xe-133) are by-products of the Mo-99 production process and will be sufficiently available if Mo-99 is available.

Approval Year

Conditions

Condition	Modality	Highest Phase	Product
Unknown 2578
bone problems 43 Sources: https://www.drugs.com/cons/osteolite.html	Diagnostic	Approved 8429	OSTEOLITE Approved Use Unknown Launch Date 1977
osteogenesis 43 Sources: https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/018035s032lbl.pdf	Diagnostic	Approved 8429	DRAXIMAGE MDP-10 Approved Use MDP-25 (Kit for the Preparation of Technetium Tc 99m Medronate) may be used as a bone imaging agent to delineate areas of altered osteogenesis. Launch Date 1978

PubMed

Title	Date	PubMed
Future of low specific activity molybdenum-99/technetium-99m generator.	2012 Oct	22642420

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:11:53 GMT 2023` Edited by `admin` on `Fri Dec 15 15:11:53 GMT 2023`
Record UNII	CQP7363UW0
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TECHNETIUM TC-99M PENTETATE CALCIUM TRISODIUM

Common Name

English

Technetium 99m trisodium calcium pentetate [WHO-DD]

Common Name

English

Technetium 99m trisodium calcium pentetate

Common Name

English

TECHNETIUM TC 99M PENTETATE CALCIUM TRISODIUM [USAN]

Common Name

English

TECHNETIUM TC 99M PENTETATE CALCIUM TRISODIUM

Official Name

English

Classification Tree Code System Code

NCI_THESAURUS

C2124

Created by admin on Fri Dec 15 15:11:53 GMT 2023 , Edited by admin on Fri Dec 15 15:11:53 GMT 2023

Code System Code Type Description

NCI_THESAURUS

C152530

Created by admin on Fri Dec 15 15:11:53 GMT 2023 , Edited by admin on Fri Dec 15 15:11:53 GMT 2023

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FDA UNII

CQP7363UW0

Created by admin on Fri Dec 15 15:11:53 GMT 2023 , Edited by admin on Fri Dec 15 15:11:53 GMT 2023

PRIMARY

PUBCHEM

121596604

Created by admin on Fri Dec 15 15:11:53 GMT 2023 , Edited by admin on Fri Dec 15 15:11:53 GMT 2023

PRIMARY

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ACTIVE MOIETY

Amount:

Details

SMILES

InChI

Approval Year

Conditions

Approved Use

Launch Date

Approved Use

Launch Date

PubMed

Patents

Sample Use Guides