4-OXOTRETINOIN

Details

Stereochemistry	ACHIRAL
Molecular Formula	C20H26O3
Molecular Weight	314.4186
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	4
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(\C=C\C1=C(C)C(=O)CCC1(C)C)=C/C=C/C(C)=C/C(O)=O

InChI

InChIKey=GGCUJPCCTQNTJF-FRCNGJHJSA-N

InChI=1S/C20H26O3/c1-14(7-6-8-15(2)13-19(22)23)9-10-17-16(3)18(21)11-12-20(17,4)5/h6-10,13H,11-12H2,1-5H3,(H,22,23)/b8-6+,10-9+,14-7+,15-13+

HIDE SMILES / InChI

Molecular Formula	C20H26O3
Molecular Weight	314.4186
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	4
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
The discovery of new coding alleles of human CYP26A1 that are potentially defective in the metabolism of all-trans retinoic acid and their assessment in a recombinant cDNA expression system.	2007-03	17460545
Beta-carotene and apocarotenals promote retinoid signaling in BEAS-2B human bronchioepithelial cells.	2006-11-01	17034753
The control of morphogen signalling: regulation of the synthesis and catabolism of retinoic acid in the developing embryo.	2005-09-01	16054125
Retinoic acid and its 4-oxo metabolites are functionally active in human skin cells in vitro.	2005-07	15982314
Discovery of new tetracyclic tetrahydrofuran derivatives as potential broad-spectrum psychotropic agents.	2005-03-24	15771415
All-trans retinoic acid is a ligand for the orphan nuclear receptor ROR beta.	2003-10	12958591
Initial retinoid requirement for early avian development coincides with retinoid receptor coexpression in the precardiac fields and induction of normal cardiovascular development.	1998-10	9786419
Generation of radical oxygen species by neural crest cells treated in vitro with isotretinoin and 4-oxo-isotretinoin.	1990	2175753

Substance Class	Chemical Created by `admin` on `Mon Mar 31 22:38:12 GMT 2025` Edited by `admin` on `Mon Mar 31 22:38:12 GMT 2025`
Record UNII	CJN45G18UA
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

RO-11-4824

Preferred Name

English

4-OXOTRETINOIN

Common Name

English

4-OXO-ATRA

Common Name

English

4-OXORETINOIC ACID

Common Name

English

RO-12-4824

Code

English

4-KETORETINOIC ACID

Common Name

English

ALL-TRANS-4-OXORETINOIC ACID

Common Name

English

4-KETO-RETINOIC ACID

Common Name

English

4-OXO-ALL-TRANS-RETINOIC ACID

Common Name

English

RETINOIC ACID, 4-OXO-

Systematic Name

English

Code System Code Type Description

FDA UNII

CJN45G18UA