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Details

Stereochemistry ACHIRAL
Molecular Formula C20H26O3
Molecular Weight 314.4186
Optical Activity UNSPECIFIED
Defined Stereocenters 0 / 0
E/Z Centers 4
Charge 0

SHOW SMILES / InChI
Structure of 4-OXOTRETINOIN

SMILES

CC(\C=C\C1=C(C)C(=O)CCC1(C)C)=C/C=C/C(C)=C/C(O)=O

InChI

InChIKey=GGCUJPCCTQNTJF-FRCNGJHJSA-N
InChI=1S/C20H26O3/c1-14(7-6-8-15(2)13-19(22)23)9-10-17-16(3)18(21)11-12-20(17,4)5/h6-10,13H,11-12H2,1-5H3,(H,22,23)/b8-6+,10-9+,14-7+,15-13+

HIDE SMILES / InChI

Molecular Formula C20H26O3
Molecular Weight 314.4186
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry
Defined Stereocenters 0 / 0
E/Z Centers 4
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Generation of radical oxygen species by neural crest cells treated in vitro with isotretinoin and 4-oxo-isotretinoin.
1990
Initial retinoid requirement for early avian development coincides with retinoid receptor coexpression in the precardiac fields and induction of normal cardiovascular development.
1998 Oct
All-trans retinoic acid is a ligand for the orphan nuclear receptor ROR beta.
2003 Oct
Retinoic acid and its 4-oxo metabolites are functionally active in human skin cells in vitro.
2005 Jul
Discovery of new tetracyclic tetrahydrofuran derivatives as potential broad-spectrum psychotropic agents.
2005 Mar 24
The control of morphogen signalling: regulation of the synthesis and catabolism of retinoic acid in the developing embryo.
2005 Sep 1
Beta-carotene and apocarotenals promote retinoid signaling in BEAS-2B human bronchioepithelial cells.
2006 Nov 1
The discovery of new coding alleles of human CYP26A1 that are potentially defective in the metabolism of all-trans retinoic acid and their assessment in a recombinant cDNA expression system.
2007 Mar
Substance Class Chemical
Created
by admin
on Tue Oct 22 17:32:05 UTC 2019
Edited
by admin
on Tue Oct 22 17:32:05 UTC 2019
Record UNII
CJN45G18UA
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
4-OXOTRETINOIN
Common Name English
4-OXO-ATRA
Common Name English
4-OXORETINOIC ACID
Common Name English
RO-12-4824
Code English
4-KETORETINOIC ACID
Common Name English
ALL-TRANS-4-OXORETINOIC ACID
Common Name English
4-KETO-RETINOIC ACID
Common Name English
4-OXO-ALL-TRANS-RETINOIC ACID
Common Name English
RO-11-4824
Code English
RETINOIC ACID, 4-OXO-
Systematic Name English
Code System Code Type Description
PUBCHEM
6437063
Created by admin on Tue Oct 22 17:32:05 UTC 2019 , Edited by admin on Tue Oct 22 17:32:05 UTC 2019
PRIMARY
CAS
38030-57-8
Created by admin on Tue Oct 22 17:32:05 UTC 2019 , Edited by admin on Tue Oct 22 17:32:05 UTC 2019
PRIMARY
Related Record Type Details
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