Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | Ga |
| Molecular Weight | 69.723 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[Ga]
InChI
InChIKey=PHMDYZQXPPOZDG-UHFFFAOYSA-N
InChI=1S/Ga.3H
| Molecular Formula | Ga |
| Molecular Weight | 69.723 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Gallium (Ga) is an element. It is a soft, slivery blue metal that becomes liquid (and silvery white) above room temperature. Gallium has been investigated for its anticancer properties since it was discovered that 67Ga(III) citrate injected in tumor-bearing animals localizes to tumor sites. Gallium has been investigated for treatment in multiple types of cancer (bladder cancer, lymphoma, multiple myeloma, paget's disease, and prostate cancer). Different generations of gallium salt are being evaluated for their antitumor efficacy and are in preclinical or clinical development. Gallium might also display antimicrobial activity, and is thought to disrupt iron homeostasis in certain bacteria and fungi.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Organogallium(III) complexes as apoptosis promoting anticancer agents for head and neck squamous cell carcinoma (HNSCC) cell lines. | 2011-02 |
|
| Gallium uptake by transferrin and interaction with receptor 1. | 2007-01 |
|
| Preclinical characterization of anticancer gallium(III) complexes: solubility, stability, lipophilicity and binding to serum proteins. | 2006-11 |
|
| Uptake of aluminum and gallium into tissues of the rat: influence of antibody against the transferrin receptor. | 1998-06-18 |
| Substance Class |
Chemical
Created
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admin
on
Edited
Mon Mar 31 19:24:30 GMT 2025
by
admin
on
Mon Mar 31 19:24:30 GMT 2025
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| Record UNII |
CH46OC8YV4
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| Record Status |
Validated (UNII)
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Systematic Name | English | ||
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Preferred Name | English | ||
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NCI_THESAURUS |
C637
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DSLD |
3352 (Number of products:30)
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C66798
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100000125930
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5360835
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1310124
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7440-55-3
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D005708
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SUB32650
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CH46OC8YV4
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CH46OC8YV4
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Gallium
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6956
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DTXSID401029758
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49631
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m5646
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231-163-8
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