Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C20H26O4 |
| Molecular Weight | 330.418 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
O=C(OC1CCCCC1)C2=CC=CC=C2C(=O)OC3CCCCC3
InChI
InChIKey=VOWAEIGWURALJQ-UHFFFAOYSA-N
InChI=1S/C20H26O4/c21-19(23-15-9-3-1-4-10-15)17-13-7-8-14-18(17)20(22)24-16-11-5-2-6-12-16/h7-8,13-16H,1-6,9-12H2
| Molecular Formula | C20H26O4 |
| Molecular Weight | 330.418 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Structure-dependent activity of phthalate esters and phthalate monoesters binding to human constitutive androstane receptor. | 2015-06-15 |
|
| Assessment of estrogenic potential of diethyl phthalate in female reproductive system involving both genomic and non-genomic actions. | 2014-11 |
|
| Enzymatic hydrolysis of structurally diverse phthalic acid esters by porcine and bovine pancreatic cholesterol esterases. | 2010-12 |
|
| An indirect competitive fluorescence immunoassay for determination of dicyclohexyl phthalate in water samples. | 2010-11 |
|
| Poly(methacrylic acid-co-ethylene glycol dimethacrylate) monolith microextraction coupled with high performance liquid chromatography for the determination of phthalate esters in cosmetics. | 2010-08-31 |
|
| Dietary intake is associated with phthalate body burden in a nationally representative sample. | 2010-07 |
|
| Environmental endocrine disruptors promote adipogenesis in the 3T3-L1 cell line through glucocorticoid receptor activation. | 2010-07 |
|
| Preparation of a chitosan-coated C(18)-functionalized magnetite nanoparticle sorbent for extraction of phthalate ester compounds from environmental water samples. | 2010-05 |
|
| Determination of phthalates in fruit jellies by dispersive SPE coupled with HPLC-MS. | 2010-02 |
|
| Structure-dependent inhibition of human and rat 11beta-hydroxysteroid dehydrogenase 2 activities by phthalates. | 2010-01-05 |
|
| Effects of in utero through lactational exposure to dicyclohexyl phthalate and p,p'-DDE in Sprague-Dawley rats. | 2009-08-25 |
|
| Differential developmental toxicities of di-n-hexyl phthalate and dicyclohexyl phthalate administered orally to rats. | 2009-08 |
|
| Medications as a potential source of exposure to phthalates in the U.S. population. | 2009-02 |
|
| Screening method for phthalate esters in water using liquid-phase microextraction based on the solidification of a floating organic microdrop combined with gas chromatography-mass spectrometry. | 2008-08-15 |
|
| Prenatal phenol and phthalate exposures and birth outcomes. | 2008-08 |
|
| Effects of possible endocrine disruptors on MyD88-independent TLR4 signaling. | 2008-03 |
|
| Phthalate levels in Norwegian indoor air related to particle size fraction. | 2007-12 |
|
| Development of dispersive liquid-liquid microextraction combined with gas chromatography-mass spectrometry as a simple, rapid and highly sensitive method for the determination of phthalate esters in water samples. | 2007-11-23 |
|
| [Simultaneous determination of phthalates and parabens in cosmetic products by gas chromatography/mass spectrometry coupled with solid phase extraction]. | 2007-03 |
|
| Simultaneous determination of seven phthalates and four parabens in cosmetic products using HPLC-DAD and GC-MS methods. | 2007-01 |
|
| Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods. | 2006-11 |
|
| Effects of possible endocrine disrupting chemicals on bacterial component-induced activation of NF-kappaB. | 2006-10 |
|
| [Determination of phthalic acid esters in textiles by solid phase extraction-gas chromatography]. | 2006-09 |
|
| [Study of dicyclohexyl phthalate on preparation and characterization of artificial antigen]. | 2006-09 |
|
| A two-generation reproductive toxicity study of dicyclohexyl phthalate in rats. | 2005-12 |
|
| Two-generation reproductive toxicity studies in rats with extra parameters for detecting endocrine disrupting activity: introductory overview of results for nine chemicals. | 2005-12 |
|
| Detection of thyroid system-disrupting chemicals using in vitro and in vivo screening assays in Xenopus laevis. | 2005-12 |
|
| Differential effects of phthalate esters on transcriptional activities via human estrogen receptors alpha and beta, and androgen receptor. | 2005-06-01 |
|
| Simultaneous screening and determination eight phthalates in plastic products for food use by sonication-assisted extraction/GC-MS methods. | 2005-04-30 |
|
| Conflict of estrogenic activity by various phthalates between in vitro and in vivo models related to the expression of Calbindin-D9k. | 2005-04 |
|
| Alteration of gene expression of G protein-coupled receptors in endocrine disruptors-caused hyperactive rats. | 2005-03-15 |
|
| Inhibitory effects of some possible endocrine-disrupting chemicals on the isozymes of human 11beta-hydroxysteroid dehydrogenase and expression of their mRNA in gonads and adrenal glands. | 2005 |
|
| Exposure to phthalate esters from indoor environment. | 2004-11 |
|
| Dicyclohexylphthalate causes hyperactivity in the rat concomitantly with impairment of tyrosine hydroxylase immunoreactivity. | 2004-10 |
|
| Suppression by phthalates of the calcium signaling of human nicotinic acetylcholine receptors in human neuroblastoma SH-SY5Y cells. | 2004-08-05 |
|
| Biodegradation of phthalate esters by two bacteria strains. | 2004-04 |
|
| Urinary levels of seven phthalate metabolites in the U.S. population from the National Health and Nutrition Examination Survey (NHANES) 1999-2000. | 2004-03 |
|
| Estimation of estrogenic and anti-estrogenic activities of some phthalate diesters and monoesters by MCF-7 cell proliferation assay in vitro. | 2003-08 |
|
| Effects and toxicity of phthalate esters to hemocytes of giant freshwater prawn, Macrobrachium rosenbergii. | 2003-06-19 |
|
| Estimated daily intake of plasticizers in 1-week duplicate diet samples following regulation of DEHP-containing PVC gloves in Japan. | 2003-04 |
|
| [Contents of plasticizers in cap-sealing for bottled food and their migration into food]. | 2002-12 |
|
| Occurrence and microbial degradation of phthalate esters in Taiwan river sediments. | 2002-12 |
|
| Effect of phthalate esters and alkylphenols on steroidogenesis in human adrenocortical H295R cells. | 2001-07 |
|
| Determination of phthalates in crude extracts of sewage sludges by high-resolution capillary gas chromatography with mass spectrometric detection. | 2001-04-28 |
|
| Effects of endocrine disrupting chemicals on the microtubule network in Chinese hamster V79 cells in culture and in Sertoli cells in rats. | 2001 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 19:14:27 GMT 2025
by
admin
on
Mon Mar 31 19:14:27 GMT 2025
|
| Record UNII |
CGD15M7H2N
|
| Record Status |
Validated (UNII)
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| Record Version |
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-
Download
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Preferred Name | English | ||
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| Classification Tree | Code System | Code | ||
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CFR |
21 CFR 176.170
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5246
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84-61-7
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6101
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DTXSID5025021
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CGD15M7H2N
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6777
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300000053249
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201-545-9
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C036042
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