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Details

Stereochemistry ACHIRAL
Molecular Formula C6H5Hg.NO3
Molecular Weight 339.7
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PHENYLMERCURIC NITRATE

SMILES

[O-][N+]([O-])=O.[Hg+]C1=CC=CC=C1

InChI

InChIKey=PDTFCHSETJBPTR-UHFFFAOYSA-N
InChI=1S/C6H5.Hg.NO3/c1-2-4-6-5-3-1;;2-1(3)4/h1-5H;;/q;+1;-1

HIDE SMILES / InChI
Molecular Formula NO3
Molecular Weight 62.0049
Charge -1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula C6H5Hg
Molecular Weight 277.69
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Phenylmercuric nitrate is classified as an antimicrobial preservative. It is bactericidal against many Gram-positive and Gram-negative species. It is used as antimicrobial preservative mainly in ophthalmic preparations. Patients who used eye drops containing the preservative, phenylmercuric nitrate for from 3 to 15 years, developed a brownish pigmentation of the anterior capsule of the pupillary area. Special studies, including electron microprobe analysis and neutron activation analysis established the presence of mercury in a lens with mercurialentis. Phenylmercuric nitrate is also an effective spermicide, although its use in vaginal contraceptives is no longer recommended.

Originator

Approval Year

1921
1467
Targets

Targets

Primary TargetPharmacologyConditionPotency
Beta-(1-4)-glucan hydrolase (Aspergillus niger)
2
Target ID: Beta-(1-4)-glucan hydrolase (Aspergillus niger)
Inhibitor
8297
Inhibitor
8297
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Diagnostic
Not Provided
504
Unknown

Approved Use

Unknown
Sourcing

Sourcing

Vendor/AggregatorIDURL
3B Scientific (Wuhan) Corp
3B2-4366
http://www.3bsc.com/index/pro_info.php?id=79306
AHH Chemical co.,ltd
MT-22399
http://www.ahhchemical.com/product/MT-22399.html
Aaron Chemicals
AR003UEV
http://www.aaronchem.com/8003-05-2
Ambinter
Amb22732287
http://www.ambinter.com/reference/22732287
BOC Sciences
6509-33-7
https://www.bocsci.com/phenyl-mercuric-nitrate-cas-6509-33-7-item-191798.html
ChemTik
CTK8J2842
Chemieliva Pharmaceutical Co., Ltd
PBCM1339007
Chemspace
CSSB00020587421
https://chem-space.com/CSSB00020587421
Finetech
FT-0603233
http://www.finetechnology-ind.com/prod/detail/pub/55-68-5.html
Lab Seeker
SC-50165
MolPort
MolPort-035-944-311
https://www.molport.com/shop/molecule-link/MolPort-035-944-311
NovoSeek
16682924
NovoSeek
9840857
PubChem
16682924
https://pubchem.ncbi.nlm.nih.gov/compound/16682924
PubChem
9840857
https://pubchem.ncbi.nlm.nih.gov/compound/9840857
Tractus
TR-025362
Tractus
TRA-0203870
Yuhao Chemical
LQ0034
http://www.chemyuhao.com/55-68-5.html
PubMed

PubMed

TitleDatePubMed
Ocular preservatives: associated risks and newer options.
2009
Temperature-mediated absorption of phenylmercuric nitrate on polyethylene and polypropylene containers in chloramphenicol eye drops.
2014 Sep
A Rare Case Report of Conjunctival Cyst.
2015 Nov
Patents

Patents

US2131008 A
2
US2366683
2
US2502222
2

Sample Use Guides

In Vivo Use Guide
Patch test - 0,01% aq.
Route of Administration: Topical
In Vitro Use Guide
The viable count of a plasmid-containing P. aeruginosa strain in Davis and Mingioli's minimal medium (DM) containing 10 ug/ml phenylmercuric nitrate fell by approximately 99% after 5 h.
Substance Class Chemical
Created
by admin
on Fri Dec 15 16:34:15 GMT 2023
Edited
by admin
on Fri Dec 15 16:34:15 GMT 2023
Record UNII
CG8692ZN14
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
PHENYLMERCURIC NITRATE
EP   HSDB   II   MART.   MI   VANDF   WHO-DD   WHO-IP  
Common Name English
Nitratophenylmercury
Common Name English
PHENYLMERCURIC NITRATE [WHO-IP]
Common Name English
PHENYLMERCURIC NITRATE [VANDF]
Common Name English
PHENYLMERCURIC NITRATE [MART.]
Common Name English
PHENYLMERCURIC NITRATE [HSDB]
Common Name English
Phenylmercuric nitrate [WHO-DD]
Common Name English
NSC-4772
Code English
PHENYLMERCURIC NITRATE [II]
Common Name English
PHENYLMERCURIC NITRATE [EP MONOGRAPH]
Common Name English
MERCURY, (NITRATO-O)PHENYL-
Common Name English
PHENYLMERCURIC NITRATE [MI]
Common Name English
PHENYLMERCURY (II) NITRATE
Systematic Name English
PHENYLHYDRARGYRI NITRAS [WHO-IP LATIN]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C1697
Created by admin on Fri Dec 15 16:34:15 GMT 2023 , Edited by admin on Fri Dec 15 16:34:15 GMT 2023
WHO-VATC QD09AA04
Created by admin on Fri Dec 15 16:34:15 GMT 2023 , Edited by admin on Fri Dec 15 16:34:15 GMT 2023
EPA PESTICIDE CODE 66016
Created by admin on Fri Dec 15 16:34:15 GMT 2023 , Edited by admin on Fri Dec 15 16:34:15 GMT 2023
WHO-ATC D09AA04
Created by admin on Fri Dec 15 16:34:15 GMT 2023 , Edited by admin on Fri Dec 15 16:34:15 GMT 2023
Code System Code Type Description
EVMPD
SUB03780MIG
Created by admin on Fri Dec 15 16:34:15 GMT 2023 , Edited by admin on Fri Dec 15 16:34:15 GMT 2023
PRIMARY
PUBCHEM
9840857
Created by admin on Fri Dec 15 16:34:15 GMT 2023 , Edited by admin on Fri Dec 15 16:34:15 GMT 2023
PRIMARY
CAS
55-68-5
Created by admin on Fri Dec 15 16:34:15 GMT 2023 , Edited by admin on Fri Dec 15 16:34:15 GMT 2023
PRIMARY
WIKIPEDIA
Phenylmercuric nitrate
Created by admin on Fri Dec 15 16:34:15 GMT 2023 , Edited by admin on Fri Dec 15 16:34:15 GMT 2023
PRIMARY
DRUG BANK
DB13388
Created by admin on Fri Dec 15 16:34:15 GMT 2023 , Edited by admin on Fri Dec 15 16:34:15 GMT 2023
PRIMARY
DAILYMED
CG8692ZN14
Created by admin on Fri Dec 15 16:34:15 GMT 2023 , Edited by admin on Fri Dec 15 16:34:15 GMT 2023
PRIMARY
FDA UNII
CG8692ZN14
Created by admin on Fri Dec 15 16:34:15 GMT 2023 , Edited by admin on Fri Dec 15 16:34:15 GMT 2023
PRIMARY
HSDB
2506
Created by admin on Fri Dec 15 16:34:15 GMT 2023 , Edited by admin on Fri Dec 15 16:34:15 GMT 2023
PRIMARY
NCI_THESAURUS
C84052
Created by admin on Fri Dec 15 16:34:15 GMT 2023 , Edited by admin on Fri Dec 15 16:34:15 GMT 2023
PRIMARY
DRUG CENTRAL
4688
Created by admin on Fri Dec 15 16:34:15 GMT 2023 , Edited by admin on Fri Dec 15 16:34:15 GMT 2023
PRIMARY
WHO INTERNATIONAL PHARMACOPEIA
PHENYLMERCURIC NITRATE
Created by admin on Fri Dec 15 16:34:15 GMT 2023 , Edited by admin on Fri Dec 15 16:34:15 GMT 2023
PRIMARY Description: White, lustrous plates or a white, crystalline powder; odourless. Solubility: Very slightly soluble in water; slightly soluble in ethanol (~750 g/l) TS; soluble in glycerol R and in fixed oils. Category: Antimicrobial preservative. Storage: Phenylmercuric nitrate should be kept in a tightly closed container, protected from light. Additional information: Phenylmercuric nitrate is affected by light. It melts at about 188 ?C with decomposition. Definition: Phenylmercuric nitrate is a mixture of phenylmercuric nitrate and phenylmercuric hydroxide. Phenylmercuric nitrate contains not less than 98.0% and not more than the equivalent of 101.0% of C12H11Hg2NO4, calculatedwith reference to the dried substance.
ECHA (EC/EINECS)
200-242-9
Created by admin on Fri Dec 15 16:34:15 GMT 2023 , Edited by admin on Fri Dec 15 16:34:15 GMT 2023
PRIMARY
RXCUI
89722
Created by admin on Fri Dec 15 16:34:15 GMT 2023 , Edited by admin on Fri Dec 15 16:34:15 GMT 2023
PRIMARY RxNorm
NSC
4772
Created by admin on Fri Dec 15 16:34:15 GMT 2023 , Edited by admin on Fri Dec 15 16:34:15 GMT 2023
PRIMARY
EPA CompTox
DTXSID6044569
Created by admin on Fri Dec 15 16:34:15 GMT 2023 , Edited by admin on Fri Dec 15 16:34:15 GMT 2023
PRIMARY
MERCK INDEX
m8683
Created by admin on Fri Dec 15 16:34:15 GMT 2023 , Edited by admin on Fri Dec 15 16:34:15 GMT 2023
PRIMARY Merck Index
NIH
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