U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Structurally Diverse
Created
by admin
on Sat Dec 16 15:42:36 GMT 2023
Edited
by admin
on Sat Dec 16 15:42:36 GMT 2023
Source Materials Class ORGANISM
Source Materials Type RECOMBINANT VIRUS
Source Materials State LIVE NON-REPLICATING GENETICALLY MODIFIED
Organism Family Parvoviridae
Organism Genus Dependoparvovirus
Organism Species adeno-associated dependoparvovirus a
Infraspecific Type RECOMBINANT VECTOR
Infraspecific Name adeno-associated virus serotype hu37 (AAVhu37) virus particle encoding the sequence for expression of B-domain deleted human factor FVIII
Part WHOLE
Record UNII
CFE96HL6SK
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
PEBOCTOCOGENE CAMAPARVOVEC
INN  
Official Name English
peboctocogene camaparvovec [INN]
Common Name English
A RECOMBINANT, NON-REPLICATING, ADENO-ASSOCIATED VIRUS SEROTYPE HU37 (AAVHU37) VECTOR, ENCODING A CODON-OPTIMISED B-DOMAIN DELETED SQ VARIANT OF HUMAN BLOOD-COAGULATION FACTOR VIII (HFVIII-SQ), UNDER THE CONTROL OF A HYBRID LIVER PROMOTER (MUS MUSCULUS T
Common Name English
DNA (RECOMBINANT ADENO-ASSOCIATED VIRUS HU37 VECTOR DTX201 MUS MUSCULUS TRANSTHYRETIN ENHANCER-HUMAN TRANSTHYRETIN PROMOTER PLUS HUMAN (1-764)-(1659-2351)-BLOOD-COAGULATION FACTOR VIII-SPECIFYING)
Common Name English
Code System Code Type Description
INN
11667
Created by admin on Sat Dec 16 15:42:36 GMT 2023 , Edited by admin on Sat Dec 16 15:42:36 GMT 2023
PRIMARY INN
CAS
2408734-39-2
Created by admin on Sat Dec 16 15:42:36 GMT 2023 , Edited by admin on Sat Dec 16 15:42:36 GMT 2023
PRIMARY
NCI_THESAURUS
C179113
Created by admin on Sat Dec 16 15:42:36 GMT 2023 , Edited by admin on Sat Dec 16 15:42:36 GMT 2023
PRIMARY
FDA UNII
CFE96HL6SK
Created by admin on Sat Dec 16 15:42:36 GMT 2023 , Edited by admin on Sat Dec 16 15:42:36 GMT 2023
PRIMARY
Related Record Type Details
ACTIVE MOIETY

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
GENE_EXPRESSION VECTOR UNSPECIFIED SUBSTANCE
7d70c1cf
(not in database)