U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Structurally Diverse
Created
by admin
on Sat Jun 26 18:54:26 UTC 2021
Edited
by admin
on Sat Jun 26 18:54:26 UTC 2021
Source Materials Class ORGANISM
Source Materials Type VIRUS
Source Materials State LIVE ATTENUATED GENETICALLY MODIFIED
Organism Family POXVIRIDAE
Organism Genus ORTHOPOXVIRUS
Organism Species VACCINIA VIRUS
Author NONE
Infraspecific Type SUBSTRAIN
Infraspecific Name LIVP (Lister strain)-GLV-1h68
Part WHOLE
Record UNII
CF19SF72O5
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
OLVIMULOGENE NANIVACIREPVEC
INN  
Official Name English
OLVIMULOGENE NANIVACIREPVEC [WHO-DD]
Common Name English
DNA (RECOMBINANT VACCINIA VIRUS STRAIN LIVP CLONE GL-ONC1)
Common Name English
GLV-1H68
Common Name English
DNA (synthetic vaccinia virus oncolytic-strain GLV-1h68 (complete genome))
Common Name English
OLVIMULOGENE NANIVACIREPVEC [USAN]
Common Name English
OLVIMULOGENE NANIVACIREPVEC [INN]
Common Name English
GL-ONC1
Code English
RECOMBINANT REPLICATION-COMPETENT ONCOLYTIC VACCINIA VIRUS VACV (LIVP STRAIN) COMPRISING INSERTION OF THE RUC-GFP, BETA-GALACTOSIDASE (LACZ) AND BETA-BLUCURONIDASE (GUSA) REPORTER GENES INTO THE F14.5L, J2R (THYMIDINE KINASE) AND A56R (HEMAGGLUTININ) LOC
Common Name English
Code System Code Type Description
NCI_THESAURUS
C79833
Created by admin on Sat Jun 26 18:54:26 UTC 2021 , Edited by admin on Sat Jun 26 18:54:26 UTC 2021
PRIMARY
INN
11165
Created by admin on Sat Jun 26 18:54:26 UTC 2021 , Edited by admin on Sat Jun 26 18:54:26 UTC 2021
PRIMARY
FDA UNII
CF19SF72O5
Created by admin on Sat Jun 26 18:54:26 UTC 2021 , Edited by admin on Sat Jun 26 18:54:26 UTC 2021
PRIMARY
CAS
1473430-36-2
Created by admin on Sat Jun 26 18:54:26 UTC 2021 , Edited by admin on Sat Jun 26 18:54:26 UTC 2021
PRIMARY
Related Record Type Details
ACTIVE MOIETY
GL-ONC1 oncolytic vaccinia virus is an immunotherapy that could cause immunogenic cell death (ICD).

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
GENE_EXPRESSION VECTOR UNSPECIFIED SUBSTANCE
3ea0dac4
(not in database)