Micvotabart Pelidotin

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National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 14:09:56 GMT 2025` Edited by `admin` on `Wed Apr 02 14:09:56 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY CONJUGATE
Protein Sub Type	IGG1\|KAPPA
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	CEJ2UDF7TX
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

H-gamma1 heavy chain Homo sapiens (1-445) [VH (Homo sapiens IGHV3-23*01 (93.9%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.9] (26-33.51-58.97-105)) (1-116) -Homo sapiens IGHG1*03v, G1m3>G1m17, nG1m1 CH1 K120, CH3 E12, M14, G1v81 CH2 C81 (CH1 R120>K (213) (1

Preferred Name

English

Micvotabart Pelidotin

Official Name

English

immunoglobulin G1-kappa, anti-[Homo sapiens FN1 (fibronectin 1) extra domain B (ED-B) splice variant], Homo sapiens monoclonal antibody, conjugated through four cysteinyl residues to a derivative of auristatin

Common Name

English

micvotabart pelidotin [INN]

Common Name

English

Code System Code Type Description

INN

13003

Created by admin on Wed Apr 02 14:09:56 GMT 2025 , Edited by admin on Wed Apr 02 14:09:56 GMT 2025

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FDA UNII

CEJ2UDF7TX

Created by admin on Wed Apr 02 14:09:56 GMT 2025 , Edited by admin on Wed Apr 02 14:09:56 GMT 2025

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NCI_THESAURUS

C200116

Created by admin on Wed Apr 02 14:09:56 GMT 2025 , Edited by admin on Wed Apr 02 14:09:56 GMT 2025

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SMS_ID

300000047957

Created by admin on Wed Apr 02 14:09:56 GMT 2025 , Edited by admin on Wed Apr 02 14:09:56 GMT 2025

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CAS

2867550-00-1

Created by admin on Wed Apr 02 14:09:56 GMT 2025 , Edited by admin on Wed Apr 02 14:09:56 GMT 2025

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From	To
4_135	4_195
4_23	4_89
3_135	3_195
3_23	3_89
2_366	2_424
2_260	2_320
2_219	4_215
2_143	2_199
2_22	2_96
1_366	1_424
1_260	1_320
1_228	2_228
1_225	2_225
1_219	3_215
1_143	1_199
1_22	1_96

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_296
N	2_296

Related Record Type Details


					CEJ2UDF7TX

Micvotabart Pelidotin

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION	[1_289] [2_289] [3_184] [4_184]	SITE_SPECIFIC	C	Amount:	UNSPECIFIED SUBSTANCE	2c1708ea (not in database)
AMINO_ACID_SUBSTITUTION	[1_1] [2_1]	N-TERMINUS	E	Amount:	PIDOLIC ACID	SZB83O1W42

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL