AMG-0347

Details

Stereochemistry	RACEMIC
Molecular Formula	C24H26F3N3O2
Molecular Weight	445.4773
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OC1CCC2=CC=CC(NC(=O)\C=C\C3=CC=C(N=C3N4CCCCC4)C(F)(F)F)=C2C1

InChI

InChIKey=YCDWBIUKUBHSKQ-FMIVXFBMSA-N

InChI=1S/C24H26F3N3O2/c25-24(26,27)21-11-8-17(23(29-21)30-13-2-1-3-14-30)9-12-22(32)28-20-6-4-5-16-7-10-18(31)15-19(16)20/h4-6,8-9,11-12,18,31H,1-3,7,10,13-15H2,(H,28,32)/b12-9+

HIDE SMILES / InChI

Molecular Formula	C24H26F3N3O2
Molecular Weight	445.4773
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	1
Optical Activity	( + / - )

Approval Year

PubMed

Title	Date	PubMed
TRPV1 receptor in expression of opioid-induced hyperalgesia.	2009-03	18774343
Nonthermal activation of transient receptor potential vanilloid-1 channels in abdominal viscera tonically inhibits autonomic cold-defense effectors.	2007-07-11	17626206

Substance Class	Chemical Created by `admin` on `Mon Mar 31 22:12:03 GMT 2025` Edited by `admin` on `Mon Mar 31 22:12:03 GMT 2025`
Record UNII	CD7L9290QR
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

2-PROPENAMIDE, 3-(2-(1-PIPERIDINYL)-6-(TRIFLUOROMETHYL)-3-PYRIDINYL)-N-(5,6,7,8-TETRAHYDRO-7-HYDROXY-1-NAPHTHALENYL)-, (2E)-

Preferred Name

English

AMG-0347

Common Name

English

Code System Code Type Description

CAS

946615-43-6

Created by admin on Mon Mar 31 22:12:03 GMT 2025 , Edited by admin on Mon Mar 31 22:12:03 GMT 2025

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FDA UNII

CD7L9290QR

Created by admin on Mon Mar 31 22:12:03 GMT 2025 , Edited by admin on Mon Mar 31 22:12:03 GMT 2025

PRIMARY

PUBCHEM

11561366

Created by admin on Mon Mar 31 22:12:03 GMT 2025 , Edited by admin on Mon Mar 31 22:12:03 GMT 2025

PRIMARY

Related Record Type Details


					CD7L9290QR

AMG-0347

ACTIVE MOIETY