Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C9H11N |
| Molecular Weight | 133.1903 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
C1CNC2=CC=CC=C2C1
InChI
InChIKey=LBUJPTNKIBCYBY-UHFFFAOYSA-N
InChI=1S/C9H11N/c1-2-6-9-8(4-1)5-3-7-10-9/h1-2,4,6,10H,3,5,7H2
| Molecular Formula | C9H11N |
| Molecular Weight | 133.1903 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| (3S)-2-Benzyl-3-carb-oxy-1,2,3,4-tetra-hydro-isoquinolinium chloride monohydrate. | 2010-12-24 |
|
| Functional importance of tyrosine 294 and the catalytic selectivity for the bis-Fe(IV) state of MauG revealed by replacement of this axial heme ligand with histidine . | 2010-11-16 |
|
| Preparation of half-metallocenes of thiophene-fused and tetrahydroquinoline-linked cyclopentadienyl ligands for ethylene/α-olefin copolymerization. | 2010-11-07 |
|
| InCl3-catalyzed allylic Friedel-Crafts reactions toward the stereocontrolled synthesis of 1,2,3,4-tetrahydroquinolines. | 2010-11-05 |
|
| Synthesis, testing and structure-activity studies on a library of 5-HT₄ ligands. | 2010-11 |
|
| Comparison of the activity of non-steroidal ecdysone agonists between dipteran and lepidopteran insects, using cell-based EcR reporter assays. | 2010-11 |
|
| Enantioselective organocatalytic C-H bond functionalization via tandem 1,5-hydride transfer/ring closure: asymmetric synthesis of tetrahydroquinolines. | 2010-09-01 |
|
| Quinoline-based compounds as modulators of HIV transcription through NF-kappaB and Sp1 inhibition. | 2010-09 |
|
| 5,8-Dimeth-oxy-2-phenyl-1,4-dihydro-quinoline-3-carbonitrile. | 2010-08-18 |
|
| A small-molecule oxocarbazate inhibitor of human cathepsin L blocks severe acute respiratory syndrome and ebola pseudotype virus infection into human embryonic kidney 293T cells. | 2010-08 |
|
| Quinaphos and Dihydro-Quinaphos phosphine-phosphoramidite ligands for asymmetric hydrogenation. | 2010-07-05 |
|
| Palladium-catalyzed ring-expansion reaction of indoles with alkynes: from indoles to tetrahydroquinoline derivatives under mild reaction conditions. | 2010-06-01 |
|
| Asymmetric three-component inverse electron-demand aza-Diels-Alder reaction: efficient synthesis of ring-fused tetrahydroquinolines. | 2010-05-17 |
|
| Highly efficient synthesis and characterization of the GPR30-selective agonist G-1 and related tetrahydroquinoline analogs. | 2010-05-07 |
|
| Diverse effects on mitochondrial and nuclear functions elicited by drugs and genetic knockdowns in bloodstream stage Trypanosoma brucei. | 2010-05-04 |
|
| Discovering some novel tetrahydroquinoline derivatives bearing the biologically active sulfonamide moiety as a new class of antitumor agents. | 2010-05 |
|
| Assessment of species specificity of moulting accelerating compounds in Lepidoptera: comparison of activity between Bombyx mori and Spodoptera littoralis by in vitro reporter and in vivo toxicity assays. | 2010-05 |
|
| Iridium-catalyzed, silyl-directed borylation of nitrogen-containing heterocycles. | 2010-03-31 |
|
| Diphosphine-catalyzed mixed double-Michael reaction: a unified synthesis of indolines, dihydropyrrolopyridines, benzimidazolines, tetrahydroquinolines, tetrahydroisoquinolines, dihydrobenzo-1,4-oxazines, and dihydrobenzo-3,1-oxazines. | 2010-03-05 |
|
| Novel tetrahydrochinoline derived CETP inhibitors. | 2010-03-01 |
|
| Zn(OTf)2-catalyzed reactions of ethenetricarboxylates with 2-aminobenzaldehydes leading to tetrahydroquinoline derivatives. | 2010-02-19 |
|
| Efficient entry into 2-substituted tetrahydroquinoline systems through alkylative ring expansion: stereoselective formal synthesis of (+/-)-martinellic acid. | 2010-02-05 |
|
| Easy access to isoquinolines and tetrahydroquinolines from ketoximes and alkynes via rhodium-catalyzed C-H bond activation. | 2009-12-18 |
|
| Tetrahydroquinoline derivatives as CRTH2 antagonists. | 2009-12-15 |
|
| N,1-Bis(4-chloro-2-methyl-benz-yl)-3-methyl-2-oxo-1,2,3,4-tetra-hydro-quinoline-3-carboxamide. | 2009-11-14 |
|
| Tetrahydroquinoline sulfonamides as vasopressin 1b receptor antagonists. | 2009-11-01 |
|
| Design, synthesis and anticancer evaluation of novel tetrahydroquinoline derivatives containing sulfonamide moiety. | 2009-10 |
|
| Substituted tetrahydroquinolines as potent allosteric inhibitors of reverse transcriptase and its key mutants. | 2009-09-01 |
|
| Gold-catalyzed intramolecular allylic amination of 2-tosylaminophenylprop-1-en-3-ols. A concise synthesis of (+/-)-angustureine. | 2009-08-21 |
|
| Design and synthesis of indole, 2,3-dihydro-indole, and 3,4-dihydro-2H-quinoline-1-carbothioic acid amide derivatives as novel HCV inhibitors. | 2009-08-01 |
|
| Improved asymmetric synthesis of 3,4-dihydro-2-[3-(1,1,2,2-tetrafluoroethoxy)phenyl]-5-[3-(trifluoromethoxy)phenyl]-alpha-(trifluoromethyl)-1(2H)-quinolineethanol, a potent cholesteryl ester transfer protein inhibitor. | 2009-07-02 |
|
| Synthesis and biotransformation of tetrahydroquinoline by Mortierella isabelina. | 2009-06-17 |
|
| Design and synthesis of potent inhibitors of cholesteryl ester transfer protein (CETP) exploiting a 1,2,3,4-tetrahydroquinoline platform. | 2009-05-01 |
|
| Self-assembly of hydrogensquarates: crystal structures and properties. | 2009-04-02 |
|
| Substituted 1,2,3,4-tetrahydroquinolin-6-yloxypropanes as beta3-adrenergic receptor agonists: design, synthesis, biological evaluation and pharmacophore modeling. | 2009-01-15 |
|
| Lewis acid or Brønsted acid catalyzed reactions of vinylidene cyclopropanes with activated carbon-nitrogen, nitrogen-nitrogen, and iodine-nitrogen double-bond-containing compounds. | 2009 |
|
| QSAR study on tetrahydroquinoline analogues as plasmodium protein farnesyltransferase inhibitors: a comparison of rationales of malarial and mammalian enzyme inhibitory activities for selectivity. | 2008-12 |
|
| Air-stable and phosphine-free iridium catalysts for highly enantioselective hydrogenation of quinoline derivatives. | 2008-11-20 |
|
| Bis(1,2,3,4-tetra-hydro-quinolin-6-yl)methane. | 2008-08-13 |
|
| Ruthenium-catalyzed enantioselective carbon-carbon bond forming reaction via allenylidene-ene process: synthetic approach to chiral heterocycles such as chromane, thiochromane, and 1,2,3,4-tetrahydroquinoline derivatives. | 2008-08-13 |
|
| Natural products as an inspiration in the diversity-oriented synthesis of bioactive compound libraries. | 2008-08 |
|
| Synthesis and characterization of 5,6,7,8-tetrahydroquinoline C5a receptor antagonists. | 2008-04-15 |
|
| Suzuki-Miyaura approach to JNJ-26076713, an orally active tetrahydroquinoline-containing alphaVbeta3/alphaVbeta5 integrin antagonist. enantioselective synthesis and stereochemical studies. | 2008-03-21 |
|
| Strictosidine synthase: mechanism of a Pictet-Spengler catalyzing enzyme. | 2008-01-16 |
|
| Selective androgen receptor modulators in preclinical and clinical development. | 2008 |
|
| Gold-catalyzed synthesis of chroman, dihydrobenzofuran, dihydroindole, and tetrahydroquinoline derivatives. | 2008 |
|
| Development of pinene-derived N,P ligands and their utility in catalytic asymmetric hydrogenation. | 2007-12-21 |
|
| Effect of ecdysone receptor gene switch ligands on endogenous gene expression in 293 cells. | 2007-11 |
|
| Heteroarotinoids with anti-cancer activity against ovarian cancer cells. | 2007-10-24 |
|
| Moexipril and left ventricular hypertrophy. | 2007 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 18:55:17 GMT 2025
by
admin
on
Mon Mar 31 18:55:17 GMT 2025
|
| Record UNII |
CCR50N1Z9G
|
| Record Status |
Validated (UNII)
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| Record Version |
|
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300000052881
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213323
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CCR50N1Z9G
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635-46-1
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69460
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211-237-6
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Tetrahydroquinoline
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C542964
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15311
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DTXSID8060903
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