U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 14:08:28 GMT 2023
Edited
by admin
on Sat Dec 16 14:08:28 GMT 2023
Protein Type TRANSPORTER
Protein Sub Type
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
CAX2OJK5R8
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
EXPORTIN-1
Common Name English
XPO1
Common Name English
CRM1
Common Name English
CHROMOSOME REGION MAINTENANCE 1 PROTEIN HOMOLOG
Common Name English
Code System Code Type Description
FDA UNII
CAX2OJK5R8
Created by admin on Sat Dec 16 14:08:28 GMT 2023 , Edited by admin on Sat Dec 16 14:08:28 GMT 2023
PRIMARY
UNIPROT
O14980
Created by admin on Sat Dec 16 14:08:28 GMT 2023 , Edited by admin on Sat Dec 16 14:08:28 GMT 2023
PRIMARY
Related Record Type Details
INHIBITOR -> TARGET
In cell-based assays, selinexor inhibits XPO1-mediated nuclear export with an IC50≈20 nM.
IC50
INHIBITOR -> TARGET
INHIBITOR -> TARGET
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL