TRIFLURALIN

Details

Stereochemistry	ACHIRAL
Molecular Formula	C13H16F3N3O4
Molecular Weight	335.279
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCCN(CCC)C1=C(C=C(C=C1[N+]([O-])=O)C(F)(F)F)[N+]([O-])=O

InChI

InChIKey=ZSDSQXJSNMTJDA-UHFFFAOYSA-N

InChI=1S/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C13H16F3N3O4
Molecular Weight	335.279
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Protective glove use and hygiene habits modify the associations of specific pesticides with Parkinson's disease.	2015-02	25461423
Comparative study of human and mouse pregnane X receptor agonistic activity in 200 pesticides using in vitro reporter gene assays.	2011-02-27	21115097
Body mass index, agricultural pesticide use, and cancer incidence in the Agricultural Health Study cohort.	2010-11	20730623
Synthesis and evaluation of oryzalin analogs against Toxoplasma gondii.	2010-09-01	20675138
Pesticide use and myocardial infarction incidence among farm women in the agricultural health study.	2010-07	20595914
Dinitroaniline activity in Toxoplasma gondii expressing wild-type or mutant alpha-tubulin.	2010-04	20145086
Toxicity of herbicides to cyanobacterial isolates.	2009-05	20120462
Mechanism of trifluralin-induced thyroid tumors in rats.	2008-07-30	18582544
Cancer incidence among pesticide applicators exposed to trifluralin in the Agricultural Health Study.	2008-06	18342850
In silico prediction of pregnane X receptor activators by machine learning approaches.	2007-01	17003167
Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods.	2006-11	16497524
Antiparasitic activity of flavonoids and isoflavones against Cryptosporidium parvum and Encephalitozoon intestinalis.	2006-06	16684116
Cellular and molecular actions of dinitroaniline and phosphorothioamidate herbicides on Plasmodium falciparum: tubulin as a specific antimalarial target.	2006-02	16406111
Environmental fate of herbicides trifluralin, metazachlor, metamitron and sulcotrione compared with that of glyphosate, a substitute broad spectrum herbicide for different glyphosate-resistant crops.	2005-09	16041722
CAR and PXR: xenosensors of endocrine disrupters?	2005-08-15	16054614
Transgenic rice containing human CYP2B6 detoxifies various classes of herbicides.	2005-05-04	15853388
Genes similar to naphthalene dioxygenase genes in trifluralin-degrading bacteria.	2004-05	15154514
Endocrine disruptors induce cytochrome P450 by affecting transcriptional regulation via pregnane X receptor.	2003-11-15	14613717
Biodegradation of the herbicide trifluralin by bacteria isolated from soil.	2003-03-01	19719679
Fate of pesticides in tropical soils of Brazil under field conditions.	2002-02-12	11837430
Effect of nutritional and environmental conditions on the production and composition of rhamnolipids by P. aeruginosa UG2.	2001-03	11297354
Dinitroaniline herbicides against protozoan parasites: the case of Trypanosoma cruzi.	2001-03	11286798
A comparison of the effects of two dinitroanilines against Cryptosporidium parvum in vitro and in vivo in neonatal mice and rats.	1999-11	10536296
Improved efficacy of dinitroaniline analogs for use as anti-cryptosporidial drugs.	1999-10-16	10519250
Assessment of drugs against Cryptosporidium parvum using a simple in vitro screening method.	1999-09-15	10499272
Synthesis and evaluation of dinitroanilines for treatment of cryptosporidiosis.	1998-02	9527782
Inhibition of Toxoplasma gondii replication by dinitroaniline herbicides.	1996-12	8948325
In vitro evaluation of anticryptosporidial agents using MDCK cell culture and chemiluminescence immunoassay.	1996-09-01	8822878
In vitro anticryptosporidial activity of dinitroaniline herbicides.	1996-03-01	8867379
Efficacy of the herbicide trifluralin against four P-glycoprotein-expressing strains of Leishmania.	1995-07	7492115
Protective effects of trifluralin on benzo(a)pyrene-induced tumors in A/J mice.	1985-02	3967235

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 17:46:02 GMT 2025` Edited by `admin` on `Mon Mar 31 17:46:02 GMT 2025`
Record UNII	C8BX46QL7K
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TRIFLURALIN

Common Name

English

.ALPHA.,.ALPHA.,.ALPHA.-TRIFLUORO-2,6-DINITRO-N,N-DIPROPYL-P-TOLUIDINE

Preferred Name

English

2,6-DINITRO-N,N-DIPROPYL-4-(TRIFLUOROMETHYL)BENZENAMINE

Systematic Name

English

TRIFLURALIN [MI]

Common Name

English

TRIFLURALIN [HSDB]

Common Name

English

TRIFLURALIN [IARC]

Common Name

English

TRIFLURALIN [ISO]

Common Name

English

Classification Tree Code System Code

EPA PESTICIDE CODE

36101