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Details

Stereochemistry ACHIRAL
Molecular Formula C18H19ClN2O2
Molecular Weight 330.809
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of HALOFENOZIDE

SMILES

CC(C)(C)N(NC(=O)C1=CC=C(Cl)C=C1)C(=O)C2=CC=CC=C2

InChI

InChIKey=CNKHSLKYRMDDNQ-UHFFFAOYSA-N
InChI=1S/C18H19ClN2O2/c1-18(2,3)21(17(23)14-7-5-4-6-8-14)20-16(22)13-9-11-15(19)12-10-13/h4-12H,1-3H3,(H,20,22)

HIDE SMILES / InChI

Molecular Formula C18H19ClN2O2
Molecular Weight 330.809
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Influence of exposure to imidacloprid on survivorship, reproduction and vitellin content of the carmine spider mite, Tetranychus cinnabarinus.
2010
N'-Benzoyl-N-tert-butyl-2-chloro-N'-{[3-(6-chloro-3-pyrid-ylmethyl)-2-nitrimino-imidazolidin-1-yl]sulfan-yl}benzo-hydrazide.
2009-08-12
Towards Coleoptera-specific high-throughput screening systems for compounds with ecdysone activity: development of EcR reporter assays using weevil (Anthonomus grandis)-derived cell lines and in silico analysis of ligand binding to A. grandis EcR ligand-binding pocket.
2009-08
Surface-applied insecticide treatments for quarantine control of Japanese beetle, Popillia japonica Newman (Coleoptera: Scarabaeidae), larvae in field-grown nursery plants.
2009-04
Evaluation of the susceptibility of the pea aphid, Acyrthosiphon pisum, to a selection of novel biorational insecticides using an artificial diet.
2009
Seasonal phenology and management of Tomarus subtropicus (Coleoptera: Scarabaeidae) in St. Augustinegrass.
2008-12
Evaluation of halofenozide against prey mosquito larvae Culex pipiens and the predator fish Gambusia affinis: impact on growth and enzymatic activities.
2008
QSAR and mode of action studies of insecticidal ecdysone agonists.
2007-03-17
Survival of adult Tiphia vernalis (Hymenoptera: Tiphiidae) after insecticide, fungicide, and herbicide exposure in laboratory bioassays.
2006-04
Cuticular hydrocarbon profiles in Blattella germanica: effects of halofenozide, boric acid and benfuracarb.
2006
Regulation of ecdysteroid signalling during Drosophila development: identification, characterization and modelling of ecdysone oxidase, an enzyme involved in control of ligand concentration.
2005-08-01
Effect of insecticides on Tiphia vernalis (Hymenoptera: Tiphiidae) oviposition and survival of progeny to cocoon stage when parasitizing Popillia japonica (Coleoptera: Scarabaeidae) larvae.
2005-06
Activity of kk-42 in combinated treatment with RH-0345 or 20-hydroxyecdysone on morphometric measurements and free ecdysteroid in eggs of mealworms.
2005
Nonsteroidal ecdysone agonists.
2005
Reproductive effects in German cockroaches by ecdysteroid agonist RH-0345, juvenile hormone analogue methoprene and carbamate benfuracarb.
2004
Ecdysone agonists: mechanism and importance in controlling insect pests of agriculture and forestry.
2003-12
Biological and chemical control of the Asiatic garden beetle, Maladera castanea (Coleoptera: Scarabaeidae).
2003-08
Toxicity and pharmacokinetics of insect growth regulators and other novel insecticides on pupae of Hyposoter didmator (Hymenoptera: Ichneumonidae), a parasitoid of early larval instars of lepidopteran pests.
2003-08
Laboratory evaluation of selective pesticides against the storage mite Tyrophagus putrescentiae (Acari: Acaridae).
2003-07
Ecdysone agonist halofenozide affects corpora allata and reproductive physiology of the Formosan subterranean termite, Coptotermes formosanus.
2003-07
Risk assessment of pesticide runoff from turf.
2003-04-24
The multicolored Asian lady beetle, Harmonia axyridis: a review of its biology, uses in biological control, and non-target impacts.
2003
Comparative effects of some ecdysteroid agonists in mealworms: ecdysteroid amounts and protein analysis in developing ovaries under in vivo conditions.
2003
Abstracts of the XV International Ecdysone Workshop. June 30- July 6, 2002. Kolymbari Crete, Greece.
2002
Insecticidal activity of a nonsteroidal moulting hormone agonist on mosquito larvae and effects on ecdysteroid amounts.
2002
Management of early-instar Japanese beetle (Coleoptera: Searabaeidae) in field-grown nursery crops.
2001-10
Neonicotinoid insecticides alter diapause behavior and survival of overwintering white grubs (Coleoptera: Scarabaeidae).
2001-09
Mobility and dissipation of ethofumesate and halofenozide in turfgrass and bare soil.
2001-06
Significance of absorption, oxidation, and binding to toxicity of four ecdysone agonists in multi-resistant cotton leafworm.
2001-03
Lethal and sublethal effects of bendiocarb, halofenozide, and imidacloprid on Harpalus pennsylvanicus (Coleoptera: Carabidae) following different modes of exposure in turfgrass.
2001-02
Impact of four insecticides on Japanese beetle (Coleoptera: Scarabaeidae) egg predators and white grubs in turfgrass.
2001-02
Comparative action of RH-0345 and pyriproxyfen on molting hormone production and protein analysis in mealworm pupae.
2001
Patents

Patents

Substance Class Chemical
Created
by admin
on Mon Mar 31 19:17:15 GMT 2025
Edited
by admin
on Mon Mar 31 19:17:15 GMT 2025
Record UNII
C81K20PELV
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
MACH 2 (DOW AGROSCI.)
Preferred Name English
HALOFENOZIDE
ISO   MI  
Common Name English
N-TERT-BUTYL-N'-(4-CHLOROBENZOYL)BENZOHYDRAZIDE
Systematic Name English
RH-0345
Code English
MACH 2
Common Name English
4-CHLOROBENZOIC ACID 2-BENZOYL-2-(1,1-DIMETHYLETHYL)HYDRAZIDE
Common Name English
HALOFENOZIDE [ISO]
Common Name English
HALOFENOZIDE [MI]
Common Name English
Classification Tree Code System Code
EPA PESTICIDE CODE 121026
Created by admin on Mon Mar 31 19:17:15 GMT 2025 , Edited by admin on Mon Mar 31 19:17:15 GMT 2025
Code System Code Type Description
PUBCHEM
114994
Created by admin on Mon Mar 31 19:17:15 GMT 2025 , Edited by admin on Mon Mar 31 19:17:15 GMT 2025
PRIMARY
ALANWOOD
halofenozide
Created by admin on Mon Mar 31 19:17:15 GMT 2025 , Edited by admin on Mon Mar 31 19:17:15 GMT 2025
PRIMARY
CAS
112226-61-6
Created by admin on Mon Mar 31 19:17:15 GMT 2025 , Edited by admin on Mon Mar 31 19:17:15 GMT 2025
PRIMARY
CHEBI
38451
Created by admin on Mon Mar 31 19:17:15 GMT 2025 , Edited by admin on Mon Mar 31 19:17:15 GMT 2025
PRIMARY
EPA CompTox
DTXSID4032619
Created by admin on Mon Mar 31 19:17:15 GMT 2025 , Edited by admin on Mon Mar 31 19:17:15 GMT 2025
PRIMARY
HSDB
7949
Created by admin on Mon Mar 31 19:17:15 GMT 2025 , Edited by admin on Mon Mar 31 19:17:15 GMT 2025
PRIMARY
MERCK INDEX
m5901
Created by admin on Mon Mar 31 19:17:15 GMT 2025 , Edited by admin on Mon Mar 31 19:17:15 GMT 2025
PRIMARY Merck Index
FDA UNII
C81K20PELV
Created by admin on Mon Mar 31 19:17:15 GMT 2025 , Edited by admin on Mon Mar 31 19:17:15 GMT 2025
PRIMARY