INPROQUONE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C16H22N2O4
Molecular Weight	306.3569
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of INPROQUONE

Structure Search

SMILES

CCCOC1=C(N2CC2)C(=O)C(OCCC)=C(N3CC3)C1=O

InChI

InChIKey=NOVZFMNCTCKLPF-UHFFFAOYSA-N

InChI=1S/C16H22N2O4/c1-3-9-21-15-11(17-5-6-17)14(20)16(22-10-4-2)12(13(15)19)18-7-8-18/h3-10H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C16H22N2O4
Molecular Weight	306.3569
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/14115688 | https://www.ncbi.nlm.nih.gov/pubmed/13994366 | https://www.ncbi.nlm.nih.gov/pubmed/14154130

Inproquone is a benzoquinone derivative used as a cytostatic and alkylating agent for cancer treatment

Approval Year

PubMed

PubMed

Title	Date	PubMed
ONCOLYSIS BY CLOSTRIDIA. III. EFFECTS OF CLOSTRIDIA AND CHEMOTHERAPEUTIC AGENTS ON RODENT TUMORS.	1964-02	14115688

Patents

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:27:20 GMT 2025` Edited by `admin` on `Mon Mar 31 18:27:20 GMT 2025`
Record UNII	C6Y700V0M4
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

E-39 (INPROQUONE)

Preferred Name

English

INPROQUONE

Official Name

English

RP 6870

Code

English

RP-6870

Code

English

inproquone [INN]

Common Name

English

2,5-BIS(ETHYLENEIMINO)-3,6-DIPROPOXY-P-BENZOQUINONE

Systematic Name

English

NSC-17261

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C274

Created by admin on Mon Mar 31 18:27:20 GMT 2025 , Edited by admin on Mon Mar 31 18:27:20 GMT 2025

Code System Code Type Description

FDA UNII

C6Y700V0M4

Created by admin on Mon Mar 31 18:27:20 GMT 2025 , Edited by admin on Mon Mar 31 18:27:20 GMT 2025

PRIMARY

EPA CompTox

DTXSID00195884

Created by admin on Mon Mar 31 18:27:20 GMT 2025 , Edited by admin on Mon Mar 31 18:27:20 GMT 2025

PRIMARY

EVMPD

SUB08193MIG

Created by admin on Mon Mar 31 18:27:20 GMT 2025 , Edited by admin on Mon Mar 31 18:27:20 GMT 2025

PRIMARY

SMS_ID

100000083419

Created by admin on Mon Mar 31 18:27:20 GMT 2025 , Edited by admin on Mon Mar 31 18:27:20 GMT 2025

PRIMARY

PUBCHEM

71627

Created by admin on Mon Mar 31 18:27:20 GMT 2025 , Edited by admin on Mon Mar 31 18:27:20 GMT 2025

PRIMARY

MESH

C026480

Created by admin on Mon Mar 31 18:27:20 GMT 2025 , Edited by admin on Mon Mar 31 18:27:20 GMT 2025

PRIMARY

ChEMBL

CHEMBL462220

Created by admin on Mon Mar 31 18:27:20 GMT 2025 , Edited by admin on Mon Mar 31 18:27:20 GMT 2025

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CAS

436-40-8

Created by admin on Mon Mar 31 18:27:20 GMT 2025 , Edited by admin on Mon Mar 31 18:27:20 GMT 2025

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INN

829

Created by admin on Mon Mar 31 18:27:20 GMT 2025 , Edited by admin on Mon Mar 31 18:27:20 GMT 2025

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NCI_THESAURUS

C65919

Created by admin on Mon Mar 31 18:27:20 GMT 2025 , Edited by admin on Mon Mar 31 18:27:20 GMT 2025

PRIMARY

NSC

17261

Created by admin on Mon Mar 31 18:27:20 GMT 2025 , Edited by admin on Mon Mar 31 18:27:20 GMT 2025

PRIMARY

Related Record Type Details


					C6Y700V0M4

ACTIVE MOIETY