CLAZOLIMINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C10H10ClN3O
Molecular Weight	223.659
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CN1C(=O)CN(C1=N)C2=CC=C(Cl)C=C2

InChI

InChIKey=TUQAUZURSHKTFF-UHFFFAOYSA-N

InChI=1S/C10H10ClN3O/c1-13-9(15)6-14(10(13)12)8-4-2-7(11)3-5-8/h2-5,12H,6H2,1H3

HIDE SMILES / InChI

Molecular Formula	C10H10ClN3O
Molecular Weight	223.659
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&ns=NCI_Thesaurus&code=C77558 | https://worldwide.espacenet.com/publicationDetails/originalDocument?FT=D&date=19740918&DB=EPODOC&locale=en_EP&CC=GB&NR=1367576A&KC=A&ND=4

Clazolimine is an imidazolidinone-based aldosterone antagonist with potassium-sparing diuretic activity. Clazolimine antagonizes aldosterone at the mineralocorticoid receptor in the kidneys, thereby increasing sodium excretion and inhibiting potassium excretion. Clazomiline was discovered by the American Cyanamid Company in the 1970s.

Approval Year

Patents

Substance Class	Chemical Created by `admin` on `Sat Dec 16 17:32:16 GMT 2023` Edited by `admin` on `Sat Dec 16 17:32:16 GMT 2023`
Record UNII	C3XSG3DLPA
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

CLAZOLIMINE

Official Name

English

CL-88893

Code

English

CLAZOLIMINE [USAN]

Common Name

English

CL 88,893

Code

English

clazolimine [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C448