Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C27H36N2O5S |
| Molecular Weight | 500.65 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CCCCNCCCOC1=CC=C(C=C1)C(=O)C2=C(CCCC)OC3=CC=C(NS(C)(=O)=O)C=C23
InChI
InChIKey=IJVZZGIAELTWBB-UHFFFAOYSA-N
InChI=1S/C27H36N2O5S/c1-4-6-9-25-26(23-19-21(29-35(3,31)32)12-15-24(23)34-25)27(30)20-10-13-22(14-11-20)33-18-8-17-28-16-7-5-2/h10-15,19,28-29H,4-9,16-18H2,1-3H3
| Molecular Formula | C27H36N2O5S |
| Molecular Weight | 500.65 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Action of specific thyroid hormone receptor α(1) and β(1) antagonists in the central and peripheral regulation of thyroid hormone metabolism in the rat. | 2012-12 |
|
| Simultaneous determination of dronedarone and its active metabolite debutyldronedarone in human plasma by liquid chromatography-tandem mass spectrometry: application to a pharmacokinetic study. | 2011-10-15 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 21:41:44 GMT 2025
by
admin
on
Mon Mar 31 21:41:44 GMT 2025
|
| Record UNII |
C3801M93QC
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Common Name | English | ||
|
Preferred Name | English | ||
|
Common Name | English | ||
|
Systematic Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Code | English | ||
|
Common Name | English | ||
|
Systematic Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
C3801M93QC
Created by
admin on Mon Mar 31 21:41:44 GMT 2025 , Edited by admin on Mon Mar 31 21:41:44 GMT 2025
|
PRIMARY | |||
|
1228541
Created by
admin on Mon Mar 31 21:41:44 GMT 2025 , Edited by admin on Mon Mar 31 21:41:44 GMT 2025
|
PRIMARY | |||
|
DTXSID60421893
Created by
admin on Mon Mar 31 21:41:44 GMT 2025 , Edited by admin on Mon Mar 31 21:41:44 GMT 2025
|
PRIMARY | |||
|
141626-35-9
Created by
admin on Mon Mar 31 21:41:44 GMT 2025 , Edited by admin on Mon Mar 31 21:41:44 GMT 2025
|
PRIMARY | |||
|
10255437
Created by
admin on Mon Mar 31 21:41:44 GMT 2025 , Edited by admin on Mon Mar 31 21:41:44 GMT 2025
|
PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
PARENT -> METABOLITE LESS ACTIVE |
Dronedarone is extensively metabolized, mainly by CYP 3A
MAJOR
PLASMA
|
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
PARENT -> IMPURITY |
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
|
