Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C27H36N2O5S |
| Molecular Weight | 500.65 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CCCCNCCCOC1=CC=C(C=C1)C(=O)C2=C(CCCC)OC3=CC=C(NS(C)(=O)=O)C=C23
InChI
InChIKey=IJVZZGIAELTWBB-UHFFFAOYSA-N
InChI=1S/C27H36N2O5S/c1-4-6-9-25-26(23-19-21(29-35(3,31)32)12-15-24(23)34-25)27(30)20-10-13-22(14-11-20)33-18-8-17-28-16-7-5-2/h10-15,19,28-29H,4-9,16-18H2,1-3H3
| Molecular Formula | C27H36N2O5S |
| Molecular Weight | 500.65 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Simultaneous determination of dronedarone and its active metabolite debutyldronedarone in human plasma by liquid chromatography-tandem mass spectrometry: application to a pharmacokinetic study. | 2011 Oct 15 |
|
| Action of specific thyroid hormone receptor α(1) and β(1) antagonists in the central and peripheral regulation of thyroid hormone metabolism in the rat. | 2012 Dec |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 07:32:23 GMT 2023
by
admin
on
Sat Dec 16 07:32:23 GMT 2023
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| Record UNII |
C3801M93QC
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| Record Status |
Validated (UNII)
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| Record Version |
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C3801M93QC
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1228541
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DTXSID60421893
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141626-35-9
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10255437
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| Related Record | Type | Details | ||
|---|---|---|---|---|
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PARENT -> METABOLITE LESS ACTIVE |
Dronedarone is extensively metabolized, mainly by CYP 3A
MAJOR
PLASMA
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| Related Record | Type | Details | ||
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PARENT -> IMPURITY |
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
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