U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Structurally Diverse
Created
by admin
on Sat Dec 16 19:33:55 GMT 2023
Edited
by admin
on Sat Dec 16 19:33:55 GMT 2023
Source Materials Class ORGANISM
Source Materials Type RECOMBINANT VIRUS
Source Materials State SELF-INACTIVATING
Organism Family Retroviridae
Organism Genus Lentivirus
Organism Species human immunodeficiency virus 1
Infraspecific Type RECOMBINANT VECTOR
Infraspecific Name SIN/LV/EF1alpha/anti-CD19 and CD22 CAR
Part whole
Record UNII
C2C748J4VR
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
Tinocabtagene autoleucel lentiviral vector
Common Name English
Tinocabtagene autoleucel lentiviral vector encoding bispecific anti-CD19 and anti-CD22 chimeric antigen receptor (CAR)
Common Name English
Code System Code Type Description
FDA UNII
C2C748J4VR
Created by admin on Sat Dec 16 19:33:55 GMT 2023 , Edited by admin on Sat Dec 16 19:33:55 GMT 2023
PRIMARY

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
INSERTED GENE EXPRESSION VECTOR Tinocabtagene autoleucel transgene insert N38C7QAA5W