U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 15:46:41 GMT 2023
Edited
by admin
on Sat Dec 16 15:46:41 GMT 2023
Protein Sub Type
Record UNII
BZY4UC5GQT
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CD273
Common Name English
PD-1 LIGAND 2
Common Name English
PD-L2
Common Name English
PROGRAMMED DEATH LIGAND 2
Common Name English
Code System Code Type Description
WIKIPEDIA
PDCD1LG2
Created by admin on Sat Dec 16 15:46:41 GMT 2023 , Edited by admin on Sat Dec 16 15:46:41 GMT 2023
PRIMARY
FDA UNII
BZY4UC5GQT
Created by admin on Sat Dec 16 15:46:41 GMT 2023 , Edited by admin on Sat Dec 16 15:46:41 GMT 2023
PRIMARY
UNIPROT
Q9BQ51
Created by admin on Sat Dec 16 15:46:41 GMT 2023 , Edited by admin on Sat Dec 16 15:46:41 GMT 2023
PRIMARY
From To
1_124 1_173
1_23 1_83
Glycosylation Type HUMAN
Glycosylation Link Type Site
N 1_18
N 1_45
N 1_138
N 1_144
N 1_170
Related Record Type Details
TARGET -> AGONIST
PD-L2 binds to its receptor PD-1 with dissociation constant Kd of 11.3 nM.[16] Binding to PD-1 can activate pathways inhibiting TCR/BCR-mediated immune cell activation
BINDING
Kd
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL