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Details

Stereochemistry ACHIRAL
Molecular Formula 2C2H3O2.3Pb.4HO
Molecular Weight 807.7
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of LEAD SUBACETATE

SMILES

[OH-].[OH-].[OH-].[OH-].[PbH2++].[PbH2++].[PbH2++].CC([O-])=O.CC([O-])=O

InChI

InChIKey=ZVYXAPIZECHZKT-UHFFFAOYSA-H
InChI=1S/2C2H4O2.4H2O.3Pb.6H/c2*1-2(3)4;;;;;;;;;;;;;/h2*1H3,(H,3,4);4*1H2;;;;;;;;;/q;;;;;;3*+2;;;;;;/p-6

HIDE SMILES / InChI

Molecular Formula HO
Molecular Weight 17.0073
Charge -1
Count
MOL RATIO 4 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C2H3O2
Molecular Weight 59.044
Charge -1
Count
MOL RATIO 2 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula Pb
Molecular Weight 207.2
Charge 2
Count
MOL RATIO 3 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Lead(II) acetate is a white crystalline chemical compound with a sweetish taste. Lead(II) acetate is used as a mordant in textile printing and dyeing, as a drier in paints and varnishes, and in preparing other lead compounds. It was historically used as a sweetener and for cosmetics.

Approval Year

Conditions

ConditionModalityTargetsHighest PhaseProduct

PubMed

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
It was examined the associations of increased glial fibrillary acidic protein (GFAP) levels and hypertrophie changes with susceptibility to toxic insult in C6 rat glioma cells. The cells were treated with serial pulses of dibutyryl-cAMP (dBcAMP) (each 48 hr) which increased levels of GFAP approximately twofold and the surface to volume ratio by approximately 1.7 times after the third pulse. This treatment reduced cell number by 22% and increased total protein by 10%. The cells were then exposed to different toxic substances [tin chloride, lead tetraacetate, chloroquine, cadmium chloride, aluminium chloride, mercuric chloride, acrylamide, triethyltin bromide, ethylenediaminetetraacetatic acid (EDTA)] and toxicity to the cells measured by the neutral red (NR) assay. With the exceptions of aluminium chloride and EDTA, 50% effective concentration (EC(50)) values for the toxic substances were increased up to 10,000 times (for cadmium chloride).
Substance Class Chemical
Record UNII
BW7DT27250
Record Status Validated (UNII)
Record Version