BISOBRIN DIHYDROCHLORIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C26H36N2O4.2ClH
Molecular Weight	513.497
Optical Activity	UNSPECIFIED
Defined Stereocenters	2 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cl.Cl.COC1=C(OC)C=C2[C@@H](CCCC[C@@H]3NCCC4=CC(OC)=C(OC)C=C34)NCCC2=C1

InChI

InChIKey=XQJUWURVXZKFST-WANFXGKWSA-N

InChI=1S/C26H36N2O4.2ClH/c1-29-23-13-17-9-11-27-21(19(17)15-25(23)31-3)7-5-6-8-22-20-16-26(32-4)24(30-2)14-18(20)10-12-28-22;;/h13-16,21-22,27-28H,5-12H2,1-4H3;2*1H/t21-,22+;;

HIDE SMILES / InChI

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C26H36N2O4
Molecular Weight	440.575
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://books.google.ru/books?id=tsjrCAAAQBAJ&pg=PA51&lpg=PA51&dq=BISOBRIN&source=bl&ots=R4QAlKOoBc&sig=ACfU3U1HqbU0bIerWQ86-06qOpkaPOC9fw&hl=ru&sa=X&ved=2ahUKEwjUhpjgiZTiAhUR7KYKHbA-Anc4ChDoATAHegQIBxAB#v=onepage&q=BISOBRIN&f=false

Bisobrin, an isoquinoline was studied as a fibrinolytic agent and has never been used therapeutically.

Approval Year

PubMed

Title	Date	PubMed
[Mechanism of action of certain fibrinolytic bis-tetrahydroisoquinolines: their antagonists and histamine- and 5-hydroxytryptamine-releasing effects (author's transl)].	1980 Jan	6155318

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:04:39 GMT 2023` Edited by `admin` on `Fri Dec 15 15:04:39 GMT 2023`
Record UNII	BU1D6Y3Q5L
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

BISOBRIN DIHYDROCHLORIDE

Common Name

English

ISOQUINOLINE, 1,1'-(1,4-BUTANEDIYL)BIS(1,2,3,4-TETRAHYDRO-6,7-DIMETHOXY-, DIHYDROCHLORIDE, (R*,S*)-

Systematic Name

English

ISOQUINOLINE, 1,1'-TETRAMETHYLENEBIS(1,2,3,4-TETRAHYDRO-6,7-DIMETHOXY-, DIHYDROCHLORIDE, MESO-

Systematic Name

English

ISOQUINOLINE, 1,1'-TETRAMETHYLENEBIS(1,2,3,4-TETRAHYDRO-6,7-DIMETHOXY-, DIHYDROCHLORIDE, (±)-

Systematic Name

English

Code System Code Type Description

PUBCHEM

91667956