U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C12H7ClO2
Molecular Weight 218.636
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 1-CHLORODIBENZO-P-DIOXIN

SMILES

ClC1=C2OC3=C(OC2=CC=C1)C=CC=C3

InChI

InChIKey=VGGGRWRBGXENKI-UHFFFAOYSA-N
InChI=1S/C12H7ClO2/c13-8-4-3-7-11-12(8)15-10-6-2-1-5-9(10)14-11/h1-7H

HIDE SMILES / InChI

Molecular Formula C12H7ClO2
Molecular Weight 218.636
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Comparison of intake and systemic relative effect potencies of dioxin-like compounds in female mice after a single oral dose.
2013-07
Toxicological application of primary hepatocyte cell cultures of Atlantic cod (Gadus morhua)--effects of BNF, PCDD and Cd.
2010-05
Aryl hydrocarbon receptor activation and overexpression upregulated fibroblast growth factor-9 in human lung adenocarcinomas.
2009-08-15
Prevalence of metabolic syndrome associated with body burden levels of dioxin and related compounds among Japan's general population.
2009-04
Ferric oxide mediated formation of PCDD/Fs from 2-monochlorophenol.
2009-01-15
Kinetics of reductive dechlorination of 1,2,3,4-TCDD in the presence of zero-valent zinc.
2008-03
In vitro toxicity assay using human bronchial epithelial cell, Beas-2B, for the screening of toxicological risk of dioxin-like compounds sampled from small sized Korean waste incineration plants.
2007-11
Levels and effects of PCDD/Fs and co-PCBs in sediments, mussels, and sea stars of the intertidal zone in the southern North Sea and the English Channel.
2006-10
Alteration of steroidogenesis in H295R cells by organic sediment contaminants and relationships to other endocrine disrupting effects.
2006-08
Formation of bromochlorodibenzo-p-dioxins and dibenzofurans from the high-temperature oxidation of a mixture of 2-chlorophenol and 2-bromophenol.
2006-05-01
Interactive effects between CYP1A1 genotypes and environmental polychlorinated dibenzo-p-dioxins and dibenzofurans exposures on liver function profile.
2006-02
Degradation of mono-chlorinated dibenzo-p-dioxins by Janibacter sp. strain YA isolated from river sediment.
2005-11
Aryl hydrocarbon receptor (AHR) and AHR nuclear translocator (ARNT) expression in Baikal seal (Pusa sibirica) and association with 2,3,7,8-TCDD toxic equivalents and CYP1 expression levels.
2005-07
Comparisons of brain, uterus, and liver mRNA expression for cytochrome p450s, DNA methyltransferase-1, and catechol-o-methyltransferase in prepubertal female Sprague-Dawley rats exposed to a mixture of aryl hydrocarbon receptor agonists.
2005-07
Inhibition of human and rat CYP1A2 by TCDD and dioxin-like chemicals.
2005-04
Mechanisms of dioxin formation from the high-temperature oxidation of 2-chlorophenol.
2005-01-01
By-side chlorodibenzo-P-dioxins and chlorodibenzofurans in technical chlorobiphenyl formulations of aroclor 1268, chlorofen, and clophen T 64.
2005
By-side impurities in chloronaphthalene mixtures of the Halowax series: all 75 chlorodibenzo-p-dioxins.
2005
Clophen A60 composition and content of CBs, CNs, CDFs, and CDDs after 2D-HPLC, HRGC/LRMS, and HRGC/HRMS separation and quantification.
2005
Effects of postnatal exposure to mixtures of non-ortho-PCBs, PCDDs, and PCDFs in prepubertal female rats.
2003-10
Correlation of cardiotoxicity mediated by halogenated aromatic hydrocarbons to aryl hydrocarbon receptor activation.
2001-05
Potency of various polycyclic aromatic hydrocarbons as inducers of CYP1A1 in rat hepatocyte cultures.
1999-01-29
Patents

Patents

Substance Class Chemical
Created
by admin
on Mon Mar 31 22:48:46 GMT 2025
Edited
by admin
on Mon Mar 31 22:48:46 GMT 2025
Record UNII
BT477ZL85J
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
PCDD 1
Preferred Name English
1-CHLORODIBENZO-P-DIOXIN
Common Name English
Code System Code Type Description
FDA UNII
BT477ZL85J
Created by admin on Mon Mar 31 22:48:46 GMT 2025 , Edited by admin on Mon Mar 31 22:48:46 GMT 2025
PRIMARY
CAS
39227-53-7
Created by admin on Mon Mar 31 22:48:46 GMT 2025 , Edited by admin on Mon Mar 31 22:48:46 GMT 2025
PRIMARY
PUBCHEM
37207
Created by admin on Mon Mar 31 22:48:46 GMT 2025 , Edited by admin on Mon Mar 31 22:48:46 GMT 2025
PRIMARY
EPA CompTox
DTXSID80872020
Created by admin on Mon Mar 31 22:48:46 GMT 2025 , Edited by admin on Mon Mar 31 22:48:46 GMT 2025
PRIMARY