| Stereochemistry | ABSOLUTE |
| Molecular Formula | C21H21N5O4 |
| Molecular Weight | 407.4225 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CCOC1=CC=CN=C1OC2=CN=CC(=C2)C3=NC=C(C=N3)C(=O)N[C@H]4CCOC4
InChI
InChIKey=UKBQFBRPXKGJPY-INIZCTEOSA-N
InChI=1S/C21H21N5O4/c1-2-29-18-4-3-6-23-21(18)30-17-8-14(9-22-12-17)19-24-10-15(11-25-19)20(27)26-16-5-7-28-13-16/h3-4,6,8-12,16H,2,5,7,13H2,1H3,(H,26,27)/t16-/m0/s1
| Molecular Formula | C21H21N5O4 |
| Molecular Weight | 407.4225 |
| Charge | 0 |
| Count |
MOL RATIO
1 MOL RATIO (average) |
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
|
|
TARGET -> INHIBITOR |
INHIBITOR
IC50
17.2 NANOMOLAR [5.05 to 58.6] (average) |
||
|
|
TRANSPORTER -> INHIBITOR |
IC50
24.3 MICROMOLAR (average) |
||
|
|
TRANSPORTER -> NON-INHIBITOR |
IC50
|
||
|
|
METABOLIC ENZYME -> INHIBITOR |
IC50
8.7 MICROMOLAR (average) |
||
|
|
TRANSPORTER -> INHIBITOR |
IC50
3.54 MICROMOLAR (average) |
Showing 1 to 5 of 7 entries
![Structure of 2-[5-[(3-Ethoxypyridin-2-yl)oxy]pyridin-3-yl]pyrimidine-5-carboxylic acid](/img/9b449e70-f882-4ed7-8fea-408d7f37fa4d.svg "Structure of 2-[5-[(3-Ethoxypyridin-2-yl)oxy]pyridin-3-yl]pyrimidine-5-carboxylic acid")
