U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 15:09:35 GMT 2023
Edited
by admin
on Sat Dec 16 15:09:35 GMT 2023
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG4
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
BPZ4A29SYE
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
PEPINEMAB
INN   USAN  
Official Name English
VX-152503
Code English
PEPINEMAB [USAN]
Common Name English
Pepinemab [WHO-DD]
Common Name English
pepinemab [INN]
Common Name English
IMMUNOGLOBULIN G4-KAPPA, ANTI-(HOMO SAPIENS SEMA4D (SEMAPHORIN 4D, CD100)), MONOCLONAL ANTIBODYGAMMA4 HEAVY CHAIN (1-445) (VH (HOMO SAPIENS IGHV1-46*01 (82.7%)-(IGHD)-IGHJ3*01 (92.9%)) (8.8.11) (1-118)-HOMO SAPIENS IGHG4*01 (CH1 (119-216), HINGE S10>P (2
Systematic Name English
VX15/2503
Code English
IMMUNOGLOBULIN G4-KAPPA, ANTI-(HOMO SAPIENS SEMAPHORINE-D4 (CD100 ANTIGEN))HUMANIZED MONOCLONAL ANTIBODY.GAMMA.4 HEAVY CHAIN (1-445) (HUMANIZED VH (HOMO SAPIENS IGHV1-46*01 (83%) (IGHD)-IGHJ3*01 (93%)) (8.8.11) (1-118)-HOMO SAPIENS IGHG4*01 (HINGE(S10>P(
Systematic Name English
IMMUNOGLOBULIN G4 (226-PROLINE), ANTI-(HUMAN SEMAPHORIN 4D)(HUMANIZED MONOCLONAL VX-15/2503 .GAMMA.4-CHAIN), DISULFIDE WITH HUMANIZED MONOCLONAL VX-15/2503 .KAPPA.-CHAIN, DIMER
Systematic Name English
ANTI-SEMA4D MONOCLONAL ANTIBODY VX15/2503
Common Name English
VX-15
Code English
VX15
Code English
MOAB VX15/2503
Code English
Classification Tree Code System Code
NCI_THESAURUS C20401
Created by admin on Sat Dec 16 15:09:36 GMT 2023 , Edited by admin on Sat Dec 16 15:09:36 GMT 2023
NCI_THESAURUS C129822
Created by admin on Sat Dec 16 15:09:36 GMT 2023 , Edited by admin on Sat Dec 16 15:09:36 GMT 2023
FDA ORPHAN DRUG 530916
Created by admin on Sat Dec 16 15:09:36 GMT 2023 , Edited by admin on Sat Dec 16 15:09:36 GMT 2023
Code System Code Type Description
DRUG BANK
DB15155
Created by admin on Sat Dec 16 15:09:36 GMT 2023 , Edited by admin on Sat Dec 16 15:09:36 GMT 2023
PRIMARY
INN
11011
Created by admin on Sat Dec 16 15:09:36 GMT 2023 , Edited by admin on Sat Dec 16 15:09:36 GMT 2023
PRIMARY
NCI_THESAURUS
C96222
Created by admin on Sat Dec 16 15:09:36 GMT 2023 , Edited by admin on Sat Dec 16 15:09:36 GMT 2023
PRIMARY
FDA UNII
BPZ4A29SYE
Created by admin on Sat Dec 16 15:09:36 GMT 2023 , Edited by admin on Sat Dec 16 15:09:36 GMT 2023
PRIMARY
USAN
FG-76
Created by admin on Sat Dec 16 15:09:36 GMT 2023 , Edited by admin on Sat Dec 16 15:09:36 GMT 2023
PRIMARY
CAS
2097151-87-4
Created by admin on Sat Dec 16 15:09:36 GMT 2023 , Edited by admin on Sat Dec 16 15:09:36 GMT 2023
PRIMARY
From To
1_22 1_96
1_132 3_218
1_145 1_201
1_224 2_224
1_227 2_227
1_259 1_319
1_365 1_423
2_22 2_96
2_132 4_218
2_145 2_201
2_259 2_319
2_365 2_423
3_23 3_92
3_138 3_198
4_23 4_92
4_138 4_198
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_295
N 2_295
Related Record Type Details
TARGET -> INHIBITOR
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL