Raludotatug Deruxtecan

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 18:04:18 GMT 2023` Edited by `admin` on `Sat Dec 16 18:04:18 GMT 2023`
Protein Type	MONOCLONAL ANTIBODY CONJUGATE
Protein Sub Type	IGG1
Sequence Type	COMPLETE
Record UNII	BPQ010OFD7
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

Raludotatug Deruxtecan

Official Name

English

immunoglobulin G1-kappa, anti-[Homo sapiens CDH6(cadherin 6, K-cadherin (foetal kidney), cadherin 6 type 2)], humanized monoclonal antibody conjugated to deruxtecan, comprising a linker and a camptothecin derivative

Common Name

English

gamma1 heavy chain humanized (1-452) [VH (Homo sapiens IGHV1-3*01 (86.7%)-(IGHD)-IGHJ4*01(93.3%), CDR-IMGT [8.8.15] (26-33.51-58.97-111))(1-122) -Homo sapiens IGHG1*03, G1m3, nG1m1 (CH1 R120 (219)(123-220), hinge 1-15 (221-235), CH2 (236-345), CH3 E12 (3

Common Name

English

DS 6000A [WHO-DD]

Common Name

English

DS6000A

Code

English

Immunoglobulin G1, anti-(human G cadherin 6) (human-Rattus norvegicus monoclonal MABU-9014a γ1-chain), complex with human-Rattus norvegicus monoclonal MABU-9014a κ-chain, dimer, octakis(thioether) with N-[6-(3-mercapto-2,5-dioxo-1-pyrrolidinyl)-1-oxohe

Common Name

English

DS-6000A

Code

English

raludotatug deruxtecan [INN]

Common Name

English

Code System Code Type Description

FDA UNII

BPQ010OFD7

Created by admin on Sat Dec 16 18:04:18 GMT 2023 , Edited by admin on Sat Dec 16 18:04:18 GMT 2023

PRIMARY

NCI_THESAURUS

C179214

Created by admin on Sat Dec 16 18:04:18 GMT 2023 , Edited by admin on Sat Dec 16 18:04:18 GMT 2023

PRIMARY

CAS

2610074-57-0

Created by admin on Sat Dec 16 18:04:18 GMT 2023 , Edited by admin on Sat Dec 16 18:04:18 GMT 2023

PRIMARY

INN

12314

Created by admin on Sat Dec 16 18:04:18 GMT 2023 , Edited by admin on Sat Dec 16 18:04:18 GMT 2023

PRIMARY

From	To
4_133	4_193
4_23	4_88
3_133	3_193
3_23	3_88
2_372	2_430
2_266	2_326
2_225	4_213
2_149	2_205
2_22	2_96
1_372	1_430
1_266	1_326
1_234	2_234
1_231	2_231
1_225	3_213
1_149	1_205
1_22	1_96

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_302
N	2_302

Related Record Type Details


					BPQ010OFD7

Raludotatug Deruxtecan

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL