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Approval Year

Unknown
149124
Substance Class Protein
Created
by admin
on Wed Apr 02 04:47:18 GMT 2025
Edited
by admin
on Wed Apr 02 04:47:18 GMT 2025
Protein Type CYTOKINE
Protein Sub Type INTERLEUKINS
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
BNO1JG5MZC
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
BEMPEGALDESLEUKIN
USAN   INN  
Official Name English
NKTR-214
Preferred Name English
bempegaldesleukin [INN]
Common Name English
NKTR-214 PRODRUG
Code English
HOMO SAPIENS INTERLEUKIN-2 VARIANT(A1>DEL, C125>S) PRODUCED IN ESCHERICHIA COLI, IN WHICH AN AVERAGE OF 6 LYSINE RESIDUES ARE N6 SUBSTITUTED WITH ((2,7-BIS((.ALPHA.-METHYLPOLY(OXYETHYLENE))CARBAMOYL)-9H-FLUOREN-9-YL)METHOXY)CARBONYL
Common Name English
INTERLEUKIN 2 (DE-1-ALANINE,125-SERINE) (RECOMBINANT HUMAN), PEGYLATED
Common Name English
BEMPEGALDESLEUKIN [USAN]
Common Name English
ALDESLEUKIN PRODRUG NKTR-214
Common Name English
Bempegaldesleukin [WHO-DD]
Common Name English
Classification Tree Code System Code
FDA ORPHAN DRUG 732720
Created by admin on Wed Apr 02 04:47:18 GMT 2025 , Edited by admin on Wed Apr 02 04:47:18 GMT 2025
Code System Code Type Description
INN
10593
Created by admin on Wed Apr 02 04:47:18 GMT 2025 , Edited by admin on Wed Apr 02 04:47:18 GMT 2025
PRIMARY
NCI_THESAURUS
C131019
Created by admin on Wed Apr 02 04:47:18 GMT 2025 , Edited by admin on Wed Apr 02 04:47:18 GMT 2025
PRIMARY
WIKIPEDIA
Bempegaldesleukin
Created by admin on Wed Apr 02 04:47:18 GMT 2025 , Edited by admin on Wed Apr 02 04:47:18 GMT 2025
PRIMARY
FDA UNII
BNO1JG5MZC
Created by admin on Wed Apr 02 04:47:18 GMT 2025 , Edited by admin on Wed Apr 02 04:47:18 GMT 2025
PRIMARY
DRUG BANK
DB15140
Created by admin on Wed Apr 02 04:47:18 GMT 2025 , Edited by admin on Wed Apr 02 04:47:18 GMT 2025
PRIMARY
USAN
GH-118
Created by admin on Wed Apr 02 04:47:18 GMT 2025 , Edited by admin on Wed Apr 02 04:47:18 GMT 2025
PRIMARY
CAS
1939126-74-5
Created by admin on Wed Apr 02 04:47:18 GMT 2025 , Edited by admin on Wed Apr 02 04:47:18 GMT 2025
PRIMARY
SMS_ID
100000182337
Created by admin on Wed Apr 02 04:47:18 GMT 2025 , Edited by admin on Wed Apr 02 04:47:18 GMT 2025
PRIMARY
From To
1_57 1_104
Related Record Type Details
BEMPEGALDESLEUKIN PEGYLATED LYSINE
CONJUGATE COMPONENT->CONJUGATE

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
PEGYLATION RESIDUE_SPECIFIC Lysine Amount: BEMPEGALDESLEUKIN PEGYLATED LYSINE 3UIH4X3VD8
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
NIH
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