BEMPEGALDESLEUKIN

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein
Protein Type	CYTOKINE
Protein Sub Type	INTERLEUKINS
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	BNO1JG5MZC
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

BEMPEGALDESLEUKIN

Official Name

English

NKTR-214

Preferred Name

English

bempegaldesleukin [INN]

Common Name

English

NKTR-214 PRODRUG

Code

English

HOMO SAPIENS INTERLEUKIN-2 VARIANT(A1>DEL, C125>S) PRODUCED IN ESCHERICHIA COLI, IN WHICH AN AVERAGE OF 6 LYSINE RESIDUES ARE N6 SUBSTITUTED WITH ((2,7-BIS((.ALPHA.-METHYLPOLY(OXYETHYLENE))CARBAMOYL)-9H-FLUOREN-9-YL)METHOXY)CARBONYL

Common Name

English

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Classification Tree

Code System

Code

Designated/Withdrawn

FDA ORPHAN DRUG

732720

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Code System

Code

Type

Description

INN

10593

PRIMARY

NCI_THESAURUS

C131019

PRIMARY

WIKIPEDIA

Bempegaldesleukin

PRIMARY

FDA UNII

BNO1JG5MZC

PRIMARY

DRUG BANK

DB15140

PRIMARY

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Subunit 0

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Related Record

Type

Details


					3UIH4X3VD8

BEMPEGALDESLEUKIN PEGYLATED LYSINE

CONJUGATE COMPONENT->CONJUGATE

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Structural Modifications

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Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
PEGYLATION		RESIDUE_SPECIFIC	Lysine	Amount: 6 PER PROTEIN (average)	BEMPEGALDESLEUKIN PEGYLATED LYSINE	3UIH4X3VD8

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Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL	ESTIMATED C690H1107O208N171S6
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL	ESTIMATED 15300 Da (average)

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