CEFOXAZOLE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C21H18ClN3O7S
Molecular Weight	491.902
Optical Activity	UNSPECIFIED
Defined Stereocenters	2 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[H][C@]12SCC(COC(C)=O)=C(N1C(=O)[C@H]2NC(=O)C3=C(C)ON=C3C4=CC=CC=C4Cl)C(O)=O

InChI

InChIKey=OCLRGULJISNUQS-OXQOHEQNSA-N

InChI=1S/C21H18ClN3O7S/c1-9-14(15(24-32-9)12-5-3-4-6-13(12)22)18(27)23-16-19(28)25-17(21(29)30)11(7-31-10(2)26)8-33-20(16)25/h3-6,16,20H,7-8H2,1-2H3,(H,23,27)(H,29,30)/t16-,20-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C21H18ClN3O7S
Molecular Weight	491.902
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/6103933 | Drugs of Today (1977), 13, (1), 38-40 | Applied Microbiology (1972), 23, (4), 765-9.

Cefoxazole is a semi-synthetic, first-generation cephalosporin with bactericidal activity against penicillin-resistant strains of S. aureus and used in the treatment of bovine mastitis.

Originator

Approval Year

PubMed

Title	Date	PubMed
Inhibitors of alpha-chymotrypsin derived from cephalosporins: structure-activity relationships.	1980 Mar	6103933

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:28:57 GMT 2023` Edited by `admin` on `Fri Dec 15 16:28:57 GMT 2023`
Record UNII	BN10X2TL6I
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

CEFOXAZOLE

Official Name

English

Cefoxazole [WHO-DD]

Common Name

English

cefoxazole [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C357