Details
Stereochemistry | ABSOLUTE |
Molecular Formula | C27H53N7O7 |
Molecular Weight | 587.7524 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 3 / 3 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
CCOC(OCC)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)CCC(=O)N[C@H](CC([O-])=O)C[N+](C)(C)C
InChI
InChIKey=JOITUBWXBFATOR-HKBOAZHASA-N
InChI=1S/C27H53N7O7/c1-8-40-26(41-9-2)20(11-10-14-30-27(28)29)33-25(39)21(15-18(3)4)32-23(36)13-12-22(35)31-19(16-24(37)38)17-34(5,6)7/h18-21,26H,8-17H2,1-7H3,(H7-,28,29,30,31,32,33,35,36,37,38,39)/t19-,20+,21+/m1/s1
Molecular Formula | C27H53N7O7 |
Molecular Weight | 587.7524 |
Charge | 0 |
Count |
|
Stereochemistry | EPIMERIC |
Additional Stereochemistry | No |
Defined Stereocenters | 3 / 3 |
E/Z Centers | 0 |
Optical Activity | UNSPECIFIED |
L-aminocarnityl-succinyl-leucyl-argininal-diethylacetal (Myodur or C101) is a compound that comprise a carrier residue that is an analog of carnitine, a linker group, and a residue of a protease inhibitor comprising an acetal derivative of the aldehyde group. Myodur is a muscle cell targeted product that inhibits calpain in an effort to preserve muscle tissue. In 2006 CepTor Corporation (OTCBB:CEPO), a development-stage biopharmaceutical company focusing on cell-targeted therapeutic products for neuromuscular and neurodegenerative diseases announced that the Office of Orphan Products Development of the Food and Drug Administration (FDA) granted orphan drug designation for Myodur for both Duchenne and Becker muscular dystrophies. Myodur development has been discontinued.
Originator
Approval Year
Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 02:03:13 GMT 2023
by
admin
on
Sat Dec 16 02:03:13 GMT 2023
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Record UNII |
BK727F83NO
|
Record Status |
Validated (UNII)
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Record Version |
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-
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FDA ORPHAN DRUG |
214405
Created by
admin on Sat Dec 16 02:03:13 GMT 2023 , Edited by admin on Sat Dec 16 02:03:13 GMT 2023
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BK727F83NO
Created by
admin on Sat Dec 16 02:03:13 GMT 2023 , Edited by admin on Sat Dec 16 02:03:13 GMT 2023
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DB06124
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DTXSID90143435
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admin on Sat Dec 16 02:03:13 GMT 2023 , Edited by admin on Sat Dec 16 02:03:13 GMT 2023
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71587904
Created by
admin on Sat Dec 16 02:03:13 GMT 2023 , Edited by admin on Sat Dec 16 02:03:13 GMT 2023
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1006685-44-4
Created by
admin on Sat Dec 16 02:03:13 GMT 2023 , Edited by admin on Sat Dec 16 02:03:13 GMT 2023
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PRIMARY |