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Details

Stereochemistry ABSOLUTE
Molecular Formula C27H53N7O7
Molecular Weight 587.7524
Optical Activity UNSPECIFIED
Defined Stereocenters 3 / 3
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of C-101

SMILES

CCOC(OCC)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)CCC(=O)N[C@H](CC([O-])=O)C[N+](C)(C)C

InChI

InChIKey=JOITUBWXBFATOR-HKBOAZHASA-N
InChI=1S/C27H53N7O7/c1-8-40-26(41-9-2)20(11-10-14-30-27(28)29)33-25(39)21(15-18(3)4)32-23(36)13-12-22(35)31-19(16-24(37)38)17-34(5,6)7/h18-21,26H,8-17H2,1-7H3,(H7-,28,29,30,31,32,33,35,36,37,38,39)/t19-,20+,21+/m1/s1

HIDE SMILES / InChI

Molecular Formula C27H53N7O7
Molecular Weight 587.7524
Charge 0
Count
Stereochemistry EPIMERIC
Additional Stereochemistry No
Defined Stereocenters 3 / 3
E/Z Centers 0
Optical Activity UNSPECIFIED

L-aminocarnityl-succinyl-leucyl-argininal-diethylacetal (Myodur or C101) is a compound that comprise a carrier residue that is an analog of carnitine, a linker group, and a residue of a protease inhibitor comprising an acetal derivative of the aldehyde group. Myodur is a muscle cell targeted product that inhibits calpain in an effort to preserve muscle tissue. In 2006 CepTor Corporation (OTCBB:CEPO), a development-stage biopharmaceutical company focusing on cell-targeted therapeutic products for neuromuscular and neurodegenerative diseases announced that the Office of Orphan Products Development of the Food and Drug Administration (FDA) granted orphan drug designation for Myodur for both Duchenne and Becker muscular dystrophies. Myodur development has been discontinued.

Approval Year

Substance Class Chemical
Created
by admin
on Sat Dec 16 02:03:13 GMT 2023
Edited
by admin
on Sat Dec 16 02:03:13 GMT 2023
Record UNII
BK727F83NO
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
C-101
Code English
L-AMINOCARNITYL-SUCCINYL-LEUCYL-ARGININAL-DIETHYLACETAL
Common Name English
3,8,11,16-TETRAAZAHEPTADECAN-1-AMINIUM, 17-AMINO-2-(CARBOXYMETHYL)-12-(DIETHOXYMETHYL)-17-IMINO-N,N,N-TRIMETHYL-9-(2-METHYLPROPYL)-4,7,10-TRIOXO-, INNER SALT, (2R,9S,12S)-
Common Name English
C101
Code English
MYODUR
Brand Name English
Classification Tree Code System Code
FDA ORPHAN DRUG 214405
Created by admin on Sat Dec 16 02:03:13 GMT 2023 , Edited by admin on Sat Dec 16 02:03:13 GMT 2023
Code System Code Type Description
FDA UNII
BK727F83NO
Created by admin on Sat Dec 16 02:03:13 GMT 2023 , Edited by admin on Sat Dec 16 02:03:13 GMT 2023
PRIMARY
DRUG BANK
DB06124
Created by admin on Sat Dec 16 02:03:13 GMT 2023 , Edited by admin on Sat Dec 16 02:03:13 GMT 2023
PRIMARY
EPA CompTox
DTXSID90143435
Created by admin on Sat Dec 16 02:03:13 GMT 2023 , Edited by admin on Sat Dec 16 02:03:13 GMT 2023
PRIMARY
PUBCHEM
71587904
Created by admin on Sat Dec 16 02:03:13 GMT 2023 , Edited by admin on Sat Dec 16 02:03:13 GMT 2023
PRIMARY
CAS
1006685-44-4
Created by admin on Sat Dec 16 02:03:13 GMT 2023 , Edited by admin on Sat Dec 16 02:03:13 GMT 2023
PRIMARY