LORZAFONE ANHYDROUS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C18H17Cl2N3O3
Molecular Weight	394.252
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CN(C(=O)CNC(=O)CN)C1=C(C=C(Cl)C=C1)C(=O)C2=C(Cl)C=CC=C2

InChI

InChIKey=RCPMGOCZIHMTRD-UHFFFAOYSA-N

InChI=1S/C18H17Cl2N3O3/c1-23(17(25)10-22-16(24)9-21)15-7-6-11(19)8-13(15)18(26)12-4-2-3-5-14(12)20/h2-8H,9-10,21H2,1H3,(H,22,24)

HIDE SMILES / InChI

Molecular Formula	C18H17Cl2N3O3
Molecular Weight	394.252
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: DOI: 10.1016/0223-5234(91)90024-H | DOI: 10.1135/cccc19892248 | Elks, J. (2014) The Dictionary of Drugs: Chemical Data, page 743, retrieved from: https://books.google.ru/books?id=0vXTBwAAQBAJ | Milne, G.W.A. (2018) Drugs: Synonyms and Properties, retrieved from: https://books.google.ru/books?id=xUlaDwAAQBAJ

Lorzafone showed a pharmacological profile similar to that of diazepam. It belongs to the novel class of ring-opened derivatives of 1,4-benzodiazepines. It is useful minor tranquilizer and muscle relaxant.

Originator

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 18:19:55 GMT 2023` Edited by `admin` on `Fri Dec 15 18:19:55 GMT 2023`
Record UNII	BI9KI838VI
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

LORZAFONE ANHYDROUS

Common Name

English

2-(2-AMINOACETAMIDO)-4'-CHLORO-2'-(O-CHLOROBENZOYL)-N-METHYLACETANILIDE

Common Name

English

lorzafone [INN]

Common Name

English

GLYCINAMIDE, GLYCYL-N-(4-CHLORO-2-(2-CHLOROBENZOYL)PHENYL)-N-METHYL-

Systematic Name

English

Code System Code Type Description

EVMPD

SUB08592MIG