ATROPINE OXIDE HYDROCHLORIDE

Details

Stereochemistry	MIXED
Molecular Formula	C17H23NO4.ClH
Molecular Weight	341.83
Optical Activity	UNSPECIFIED
Defined Stereocenters	3 / 5
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of ATROPINE OXIDE HYDROCHLORIDE

Structure Search

SMILES

Cl.C[N+]1([O-])[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)C(CO)C3=CC=CC=C3

InChI

InChIKey=QTRBWTMEQQSFLO-CUNABDNDSA-N

InChI=1S/C17H23NO4.ClH/c1-18(21)13-7-8-14(18)10-15(9-13)22-17(20)16(11-19)12-5-3-2-4-6-12;/h2-6,13-16,19H,7-11H2,1H3;1H/t13-,14+,15+,16?,18?;

HIDE SMILES / InChI

Molecular Formula	C17H23NO4
Molecular Weight	305.3688
Charge	0
Count

Stereochemistry	MIXED
Additional Stereochemistry	No
Defined Stereocenters	3 / 5
E/Z Centers	0
Optical Activity	UNSPECIFIED

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: http://www.genome.jp/dbget-bin/www_bget?dr:D03011 | https://edkb.fda.gov/webstart/arraytrack/PDFfile/LTKB_BD/atropine.pdf

Atropine-N-oxide hydrochloride is an alkaloid of the belladonna plants. It is the major metabolite of atropine. It is a competitive nonselective antagonist at central and peripheral muscarinic acetylcholine receptors.

Originator

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Muscarinic acetylcholine receptor 160 Target ID: CHEMBL2094109 Sources: http://www.genome.jp/dbget-bin/www_bget?dr:D03011	Antagonist 2778

Conditions

Condition	Modality	Targets	Highest Phase	Product
Ophthalmic disorder 2 Sources: https://www.google.com/patents/US9421199	Primary		Basic research	Unknown Approved Use Unknown

PubMed

Title	Date	PubMed

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Sat Dec 16 05:43:28 GMT 2023` Edited by `admin` on `Sat Dec 16 05:43:28 GMT 2023`
Record UNII	BI6GBW93CA
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ATROPINE OXIDE HYDROCHLORIDE

Official Name

English

AMINOXYTROPINE TROPATE HYDROCHLORIDE

Common Name

English

ATROPINE OXIDE HYDROCHLORIDE [USAN]

Common Name

English

BENZENEACETIC ACID, .ALPHA.-(HYDROXYMETHYL)-8-METHYL-8-AZABICYCLO(3.2.1)OCT-3-YL ESTER, 8-OXIDE, HYDROCHLORIDE, ENDO-(±)-

Common Name

English

1.ALPHA.H,5.ALPHA.H-TROPAN-3.ALPHA.-OL (±)-TROPATE(ESTER) 8-OXIDE HYDROCHLORIDE

Common Name

English

Atropine n-oxide hydrochloride [WHO-DD]

Common Name

English

ATROPINE OXIDE HCL

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29704