ATROPINE OXIDE HYDROCHLORIDE

Details

Stereochemistry	MIXED
Molecular Formula	C17H23NO4.ClH
Molecular Weight	341.83
Optical Activity	UNSPECIFIED
Defined Stereocenters	3 / 5
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of ATROPINE OXIDE HYDROCHLORIDE

Structure Search

SMILES

Cl.C[N+]1([O-])[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)C(CO)C3=CC=CC=C3

InChI

InChIKey=QTRBWTMEQQSFLO-CUNABDNDSA-N

InChI=1S/C17H23NO4.ClH/c1-18(21)13-7-8-14(18)10-15(9-13)22-17(20)16(11-19)12-5-3-2-4-6-12;/h2-6,13-16,19H,7-11H2,1H3;1H/t13-,14+,15+,16?,18?;

HIDE SMILES / InChI

Molecular Formula	C17H23NO4
Molecular Weight	305.3688
Charge	0
Count

Stereochemistry	MIXED
Additional Stereochemistry	No
Defined Stereocenters	3 / 5
E/Z Centers	0
Optical Activity	UNSPECIFIED

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: http://www.genome.jp/dbget-bin/www_bget?dr:D03011 | https://edkb.fda.gov/webstart/arraytrack/PDFfile/LTKB_BD/atropine.pdf

Atropine-N-oxide hydrochloride is an alkaloid of the belladonna plants. It is the major metabolite of atropine. It is a competitive nonselective antagonist at central and peripheral muscarinic acetylcholine receptors.

Originator

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Muscarinic acetylcholine receptor 160 Target ID: CHEMBL2094109 Sources: http://www.genome.jp/dbget-bin/www_bget?dr:D03011	Antagonist 2778

Conditions

Condition	Modality	Targets	Highest Phase	Product
Ophthalmic disorder 2 Sources: https://www.google.com/patents/US9421199	Primary		Basic research	Unknown Approved Use Unknown

PubMed

Title	Date	PubMed
The metabolism of atropine in man.	1986 Oct	2879005

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Sat Dec 16 05:43:28 GMT 2023` Edited by `admin` on `Sat Dec 16 05:43:28 GMT 2023`
Record UNII	BI6GBW93CA
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ATROPINE OXIDE HYDROCHLORIDE

Official Name

English

AMINOXYTROPINE TROPATE HYDROCHLORIDE

Common Name

English

ATROPINE OXIDE HYDROCHLORIDE [USAN]

Common Name

English

BENZENEACETIC ACID, .ALPHA.-(HYDROXYMETHYL)-8-METHYL-8-AZABICYCLO(3.2.1)OCT-3-YL ESTER, 8-OXIDE, HYDROCHLORIDE, ENDO-(±)-

Common Name

English

1.ALPHA.H,5.ALPHA.H-TROPAN-3.ALPHA.-OL (±)-TROPATE(ESTER) 8-OXIDE HYDROCHLORIDE

Common Name

English

Atropine n-oxide hydrochloride [WHO-DD]

Common Name

English

ATROPINE OXIDE HCL

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29704