METHYL PIVALATE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C6H12O2
Molecular Weight	116.1583
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

COC(=O)C(C)(C)C

InChI

InChIKey=CNMFHDIDIMZHKY-UHFFFAOYSA-N

InChI=1S/C6H12O2/c1-6(2,3)5(7)8-4/h1-4H3

HIDE SMILES / InChI

Molecular Formula	C6H12O2
Molecular Weight	116.1583
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Enhanced stability and intracellular accumulation of quercetin by protection of the chemically or metabolically susceptible hydroxyl groups with a pivaloxymethyl (POM) promoiety.	2010-12-23	21090565
Chemical synthesis of RNA with base-labile 2'-o-(pivaloyloxymethyl)-protected ribonucleoside phosphoramidites.	2010-12	21154530
[Synthetic studies of imidazole C-nucleosides toward biofunctional molecules].	2010-12	21139399
Synthesis of ester prodrugs of 9-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]-2,6-diaminopurine (HPMPDAP) as anti-poxvirus agents.	2010-10-14	20809641
Synthesis and hybridization properties of oligonucleotides having 4-N-(pyrrol-2-ylcarbonyl)deoxycytidine.	2009	19749287
(2SR,4aSR,8aSR)-6-Oxoperhydro-naphthalene-2-carboxylic acid.	2008-12-20	21581624
Pivaloyloxymethyl-modified isoprenoid bisphosphonates display enhanced inhibition of cellular geranylgeranylation.	2008-04-01	18308574
Hydralazine target: from blood vessels to the epigenome.	2006-02-28	16507100
Prodrug forms of N-[(4-deoxy-4-amino-10-methyl)pteroyl]glutamate-gamma-[psiP(O)(OH)]-glutarate, a potent inhibitor of folylpoly-gamma-glutamate synthetase: synthesis and hydrolytic stability.	2006-01-26	16420062
Bioreversible quaternary N-acyloxymethyl derivatives of the poorly soluble tertiary amine Lu 28-179--synthesis, pharmaceutical chemical characterization and bioavailability studies in dogs.	2005-12	16150581
Epigenetics of cervical cancer. An overview and therapeutic perspectives.	2005-10-25	16248899
Influence of esterification and modification of A-ring in a group of lupane acids on their cytotoxicity.	2005-10-01	16087342
Synthesis of acyloxymethyl ester prodrugs of the transferable protein farnesyl transferase substrate farnesyl methylenediphosphonate.	2004-10-04	15341963
In situ observation of the four-step dehydration process of the 1 beta-methylcarbapenem antibiotic CS-834 crystal by X-rays.	2003-12	14646309
Cell handling, membrane-binding properties, and membrane-penetration modeling approaches of pivampicillin and phthalimidomethylampicillin, two basic esters of ampicillin, in comparison with chloroquine and azithromycin.	2003-04	12739771
Synthesis of helix 69 of Escherichia coli 23S rRNA containing its natural modified nucleosides, m(3)Psi and Psi.	2002-12-13	12467398
Pivalase catalytic antibodies: towards abzymatic activation of prodrugs.	2001-11-05	11757652
AS-924, a novel, orally active, bifunctional prodrug of ceftizoxime: physicochemical properties, oral absorption in animals, and antibacterial activity.	2001-11	11711261
Antimycobacterial activity of substituted isosteres of pyridine- and pyrazinecarboxylic acids. 2.	2001-05-10	11334565

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 21:12:05 GMT 2025` Edited by `admin` on `Mon Mar 31 21:12:05 GMT 2025`
Record UNII	BFX9W386OX
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

PROPANOIC ACID, 2,2-DIMETHYL-, METHYL ESTER

Preferred Name

English

METHYL PIVALATE

Systematic Name

English

METHYL TRIMETHYLACETATE

Systematic Name

English

Code System Code Type Description

ECHA (EC/EINECS)

209-959-1