Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C6H8O5 |
| Molecular Weight | 160.1247 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
OC(=O)CCCC(=O)C(O)=O
InChI
InChIKey=FGSBNBBHOZHUBO-UHFFFAOYSA-N
InChI=1S/C6H8O5/c7-4(6(10)11)2-1-3-5(8)9/h1-3H2,(H,8,9)(H,10,11)
| Molecular Formula | C6H8O5 |
| Molecular Weight | 160.1247 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Analysis of the rice mitochondrial carrier family reveals anaerobic accumulation of a basic amino acid carrier involved in arginine metabolism during seed germination. | 2010-10 |
|
| Integration of metabolomics and transcriptomics data to aid biomarker discovery in type 2 diabetes. | 2010-05 |
|
| Involvement of an alternatively spliced mitochondrial oxodicarboxylate carrier in adipogenesis in 3T3-L1 cells. | 2009-10-13 |
|
| Site-directed mutagenesis as a probe of the acid-base catalytic mechanism of homoisocitrate dehydrogenase from Saccharomyces cerevisiae. | 2009-08-04 |
|
| Mechanism for multiple-substrates recognition of alpha-aminoadipate aminotransferase from Thermus thermophilus. | 2009-05-01 |
|
| Adenine nucleotide translocator transports haem precursors into mitochondria. | 2008-08-27 |
|
| Substrate specificity and structure of human aminoadipate aminotransferase/kynurenine aminotransferase II. | 2008-08 |
|
| Structure-function relationships in the 2-oxo acid dehydrogenase family: substrate-specific signatures and functional predictions for the 2-oxoglutarate dehydrogenase-like proteins. | 2008-05-01 |
|
| Chemical mechanism of homoisocitrate dehydrogenase from Saccharomyces cerevisiae. | 2008-04-01 |
|
| Thiahomoisocitrate: a highly potent inhibitor of homoisocitrate dehydrogenase involved in the alpha-aminoadipate pathway. | 2008-03-15 |
|
| Reconstruction and flux analysis of coupling between metabolic pathways of astrocytes and neurons: application to cerebral hypoxia. | 2007-12-10 |
|
| Determinants of substrate specificity for saccharopine dehydrogenase from Saccharomyces cerevisiae. | 2007-06-26 |
|
| Purification and characterization of the FeII- and alpha-ketoglutarate-dependent xanthine hydroxylase from Aspergillus nidulans. | 2007-05-08 |
|
| Substrate specificity analysis and inhibitor design of homoisocitrate dehydrogenase. | 2007-02-01 |
|
| Excess dietary lysine increases growth of chicks fed niacin-deficient diets, but dietary quinolinic acid has no niacin-sparing activity. | 2007-02 |
|
| Complete kinetic mechanism of homoisocitrate dehydrogenase from Saccharomyces cerevisiae. | 2007-01-23 |
|
| Growth control of the eukaryote cell: a systems biology study in yeast. | 2007 |
|
| Quantitative acylcarnitine profiling in peripheral blood mononuclear cells using in vitro loading with palmitic and 2-oxoadipic acids: biochemical confirmation of fatty acid oxidation and organic acid disorders. | 2005-11 |
|
| Lysine is catabolized to 2-aminoadipic acid in Penicillium chrysogenum by an omega-aminotransferase and to saccharopine by a lysine 2-ketoglutarate reductase. Characterization of the omega-aminotransferase. | 2005-10 |
|
| Increasing mitochondrial substrate-level phosphorylation can rescue respiratory growth of an ATP synthase-deficient yeast. | 2005-09-02 |
|
| Thiamine-responsive congenital lactic acidosis: clinical and biochemical studies. | 2005-08 |
|
| alpha-Aminoadipate aminotransferase from an extremely thermophilic bacterium, Thermus thermophilus. | 2004-07 |
|
| Different elongation pathways in the biosynthesis of acyl groups of trichome exudate sugar esters from various solanaceous plants. | 2003-04 |
|
| Characterization of homoisocitrate dehydrogenase involved in lysine biosynthesis of an extremely thermophilic bacterium, Thermus thermophilus HB27, and evolutionary implication of beta-decarboxylating dehydrogenase. | 2003-01-17 |
|
| Isolation and biochemical characterization of hypophosphite/2-oxoglutarate dioxygenase. A novel phosphorus-oxidizing enzyme from Psuedomonas stutzeri WM88. | 2002-10-11 |
|
| Characterization of the human gene encoding alpha-aminoadipate aminotransferase (AADAT). | 2002-07 |
|
| Ammonia assimilation in Klebsiella pneumoniae F-5-2 that can utilize ammonium and nitrate ions simultaneously: purification and characterization of glutamate dehydrogenase and glutamine synthetase. | 2002 |
|
| A Korean girl with alpha-aminoadipic and alpha-ketoadipic aciduria accompanied with elevation of 2-hydroxyglutarate and glutarate. | 2001-08 |
|
| Gas chromatographic-mass spectrometric screening for organic acidemias using dried urine filter paper: determination of alpha-ketoacids. | 2001-07-05 |
|
| Alteration of the co-substrate selectivity of deacetoxycephalosporin C synthase. The role of arginine 258. | 2001-05-25 |
|
| Identification of the human mitochondrial oxodicarboxylate carrier. Bacterial expression, reconstitution, functional characterization, tissue distribution, and chromosomal location. | 2001-03-16 |
|
| Identification in Saccharomyces cerevisiae of two isoforms of a novel mitochondrial transporter for 2-oxoadipate and 2-oxoglutarate. | 2001-01-19 |
|
| Gas chromatographic-mass spectrometric determination of urinary oxoacids using O-(2,3,4,5,6-pentafluorobenzyl)oxime-trimethylsilyl ester derivatization and cation-exchange chromatography. | 1998-11-20 |
|
| Age-related reference values for urinary organic acids in a healthy Turkish pediatric population. | 1994-06 |
|
| Enzymatic formation of alpha-ketoadipic acid from homoisocitric acid. | 1965-11 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 20:48:21 GMT 2025
by
admin
on
Mon Mar 31 20:48:21 GMT 2025
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| Record UNII |
BB72FKL1M2
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| Record Status |
Validated (UNII)
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| Record Version |
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BB72FKL1M2
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15753
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C001918
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DTXSID20185702
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3184-35-8
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71
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alpha-Ketoadipic acid
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