Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C7H5NS2.C2H7NO |
| Molecular Weight | 228.334 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
NCCO.S=C1NC2=CC=CC=C2S1
InChI
InChIKey=BGZRCNAAUWQNRX-UHFFFAOYSA-N
InChI=1S/C7H5NS2.C2H7NO/c9-7-8-5-3-1-2-4-6(5)10-7;3-1-2-4/h1-4H,(H,8,9);4H,1-3H2
| Molecular Formula | C2H7NO |
| Molecular Weight | 61.0831 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | C7H5NS2 |
| Molecular Weight | 167.251 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
DescriptionSources: https://www.cdc.gov/niosh/docs/2014-142/pdfs/2014-142.pdf | https://hazmap.nlm.nih.gov/category-details?table=copytblagents&id=7051 | http://www.emeraldmaterials.com/cms/polyadd/fis_ftp.downloadMSDS?p_filename=NAMBT_GOOD-RITE_%20SODIUM%20MBT%20Corrosion%20Inhibitor_GHS%20Internatl_English_POLADD.pdfhttps://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=6bead357-f409-47aa-8cdd-d8676b7a5960Curator's Comment: description was created based on several sources, including
https://www.ncbi.nlm.nih.gov/pubmed/19158128
https://www.ncbi.nlm.nih.gov/pubmed/12732904
Sources: https://www.cdc.gov/niosh/docs/2014-142/pdfs/2014-142.pdf | https://hazmap.nlm.nih.gov/category-details?table=copytblagents&id=7051 | http://www.emeraldmaterials.com/cms/polyadd/fis_ftp.downloadMSDS?p_filename=NAMBT_GOOD-RITE_%20SODIUM%20MBT%20Corrosion%20Inhibitor_GHS%20Internatl_English_POLADD.pdfhttps://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=6bead357-f409-47aa-8cdd-d8676b7a5960
Curator's Comment: description was created based on several sources, including
https://www.ncbi.nlm.nih.gov/pubmed/19158128
https://www.ncbi.nlm.nih.gov/pubmed/12732904
2-Mercaptobenzothiazole (MBT) can be a human carcinogen. It causes allergic contact dermatitis. For external animal use only: for Dogs, Cats and Horses it’s used to afford relief to certain common skin problems sometimes referred to as summer eczema, kennel itch, or hot spots (moist dermatitis). These conditions are characterized by intense itching and scratching, followed by rough scaly skin, and hair loss. Skin Balm relieves itching, softens the skin and helps return your animals' coat and skin to a healthy state.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Usefulness of patch tests for diagnosing selective allergy to captopril. | 2001 |
|
| Contact dermatitis in students practicing sports: incidence of rubber sensitisation. | 2001 Apr |
|
| [Residual chemicals in natural rubber products for food contact use]. | 2001 Jun |
|
| Modified short-term guinea pig sensitization tests for detecting contact allergens as an alternative to the conventional test. | 2001 Mar |
|
| Determination of the sensitising activity of the rubber contact sensitisers TMTD, ZDMC, MBT and DEA in a modified local lymph node assay and the effect of sodium dodecyl sulfate pretreatment on local lymph node responses. | 2002 Jul 1 |
|
| Evaluation of a carbon paste electrode modified with organofunctionalized amorphous silica in the cadmium determination in a differential pulse anodic stripping voltammetric procedure. | 2003 Apr 10 |
|
| Common shoe allergens undetected by commercial patch-testing kits: dithiodimorpholine and isocyanates. | 2003 Jun |
|
| Studies in polyphenol chemistry and bioactivity. 4.(1) Synthesis of trimeric, tetrameric, pentameric, and higher oligomeric epicatechin-derived procyanidins having all-4beta,8-interflavan connectivity and their inhibition of cancer cell growth through cell cycle arrest. | 2003 Mar 7 |
|
| Occupational allergic contact dermatitis from xanthates and carbamates in mining processes. | 2003 Sep |
|
| Migration of N-nitrosamines, N-nitrosatable substances and 2-mercaptobenzthiazol from baby bottle teats and soothers: a Dutch retail survey. | 2003 Sep |
|
| [Allergy to mercaptobenzothiazole and mercapto mix]. | 2004 Aug-Sep |
|
| [Contact dermatitis from polyacrylate in TENS electrode]. | 2004 May |
|
| Determination of 2-mercaptobenzothiazole (MBT) in tannery wastewater by high performance liquid chromatography with amperometric detection. | 2004 Nov |
|
| Metabolism of 2-mercaptobenzothiazole by Rhodococcus rhodochrous. | 2004 Oct |
|
| A comparative study of the sensitivity of the 3-induction and 9-induction Buehler test procedures for assessing skin sensitisation potential. | 2005 Jan |
|
| [Evidence-based evaluation of the effect of Type IV Allergies on the reduction of fitness for work. Survey of occupational skin diseases]. | 2005 Mar |
|
| Reactions Between Chalcogen Donors and Dihalogens/Interalogens: Typology of Products and Their Characterization by FT-Raman Spectroscopy. | 2006 |
|
| MIP-1beta, a novel biomarker for in vitro sensitization test using human monocytic cell line. | 2006 Aug |
|
| FTIR, Raman spectra and ab initio calculations of 2-mercaptobenzothiazole. | 2006 Feb |
|
| Mercaptobenzothiazole or the mercapto-mix: which should be in the standard series? | 2006 Jul |
|
| Bikini dermatitis due to mercaptobenzothiazole. | 2006 Jun |
|
| Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods. | 2006 Nov |
|
| Very small and soft scorpionates: water stable technetium tricarbonyl complexes combining a bis-agostic (k(3)-H, H, S) binding motif with pendant and integrated bioactive molecules. | 2006 Nov 15 |
|
| Condom leukoderma. | 2006 Nov-Dec |
|
| High-performance liquid chromatography analysis of rubber allergens in protective gloves used in health care. | 2006 Oct |
|
| Respective contributions of polar vs enthalpy effects in the addition/fragmentation of mercaptobenzoxazole-derived thiyl radicals and analogues to double bonds. | 2006 Oct 19 |
|
| Predicting the efficiencies of 2-mercaptobenzothiazole collectors used as chelating agents in flotation processes: a density-functional study. | 2006 Sep |
|
| The nature of the chemical bond in linear three-body systems: from i3- to mixed chalcogen/halogen and trichalcogen moieties. | 2007 |
|
| Fmoc-2-mercaptobenzothiazole, for the introduction of the Fmoc moiety free of side-reactions. | 2007 |
|
| Zebrafish as a new model for phenotype-based screening of melanogenic regulatory compounds. | 2007 Apr |
|
| Oxidation of 2-mercaptobenzothiazole in latex gloves and its possible haptenation pathway. | 2007 Aug |
|
| Comparison of the adsorption orientation for 2-mercaptobenzothiazole and 2-mercaptobenzoxazole by SERS spectroscopy. | 2007 Dec 31 |
|
| Matrix-assisted laser desorption/ionization-mass spectrometry of hydrophobic proteins in mixtures using formic acid, perfluorooctanoic acid, and sorbitol. | 2007 Feb 1 |
|
| Synthesis, structural characterization, and biological studies of six- and five-coordinate organotin(IV) complexes with the thioamides 2-mercaptobenzothiazole, 5-chloro-2-mercaptobenzothiazole, and 2-mercaptobenzoxazole. | 2007 Feb 19 |
|
| Structural identification and characterization of impurities in ceftizoxime sodium. | 2007 Jan 17 |
|
| Acetylcholinesterase-polyaniline biosensor investigation of organophosphate pesticides in selected organic solvents. | 2007 Mar-Apr |
|
| Contact dermatitis to a rubber allergen with both dithiocarbamate and benzothiazole structure. | 2007 May |
|
| Epidemio-allergological study in 155 cases of footwear dermatitis. | 2007 Sep-Oct |
|
| Patch testing experience with 1000 patients. | 2007 Sep-Oct |
|
| Profiling and imaging of lipids on brain and liver tissue by matrix-assisted laser desorption/ ionization mass spectrometry using 2-mercaptobenzothiazole as a matrix. | 2008 Dec 1 |
|
| The effective and specific isolation of antibodies from human serum by using thiophilic paramagnetic polymer beads. | 2008 Dec 1 |
|
| A collaborative epidemiological investigation into the criminal fake artesunate trade in South East Asia. | 2008 Feb |
|
| A combined patch-clamp and electrorotation study of the voltage- and frequency-dependent membrane capacitance caused by structurally dissimilar lipophilic anions. | 2008 Jan |
|
| Positive patch-test reactions to mixed dialkyl thioureas: cross-sectional data from the North American Contact Dermatitis Group, 1994 to 2004. | 2008 Jul-Aug |
|
| The oxidative degradation of 2-mercaptobenzothiazole at the interface of beta-MnO2 and water. | 2008 Jun 15 |
|
| North American Contact Dermatitis Group patch-test results, 2003-2004 study period. | 2008 May-Jun |
|
| Bladder cancer risks in workers manufacturing chemicals for the rubber industry. | 2008 Oct |
Patents
Sample Use Guides
Rabbits: the dermal
LD50 value (the dose resulting in 50% mortality
in the exposed animals) for the rabbit has
been reported to be greater than 5010 mg/kg
Rats: Oral LD50: 2100 mg/kg
Route of Administration:
Other
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 07:54:27 GMT 2023
by
admin
on
Sat Dec 16 07:54:27 GMT 2023
|
| Record UNII |
B9KE7SN83F
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Systematic Name | English | ||
|
Systematic Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Code | English |
| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
|
EPA PESTICIDE CODE |
51706
Created by
admin on Sat Dec 16 07:54:27 GMT 2023 , Edited by admin on Sat Dec 16 07:54:27 GMT 2023
|
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
DTXSID5058432
Created by
admin on Sat Dec 16 07:54:27 GMT 2023 , Edited by admin on Sat Dec 16 07:54:27 GMT 2023
|
PRIMARY | |||
|
227-597-2
Created by
admin on Sat Dec 16 07:54:27 GMT 2023 , Edited by admin on Sat Dec 16 07:54:27 GMT 2023
|
PRIMARY | |||
|
68089
Created by
admin on Sat Dec 16 07:54:27 GMT 2023 , Edited by admin on Sat Dec 16 07:54:27 GMT 2023
|
PRIMARY | |||
|
3037135
Created by
admin on Sat Dec 16 07:54:27 GMT 2023 , Edited by admin on Sat Dec 16 07:54:27 GMT 2023
|
PRIMARY | |||
|
5902-85-2
Created by
admin on Sat Dec 16 07:54:27 GMT 2023 , Edited by admin on Sat Dec 16 07:54:27 GMT 2023
|
PRIMARY | |||
|
B9KE7SN83F
Created by
admin on Sat Dec 16 07:54:27 GMT 2023 , Edited by admin on Sat Dec 16 07:54:27 GMT 2023
|
PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
|
PARENT -> SALT/SOLVATE |
|
