Details
Stereochemistry | ACHIRAL |
Molecular Formula | C15H23N3O2.ClH |
Molecular Weight | 313.823 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
Cl.CCN(CC)CCNC(=O)C1=CC=C(NC(C)=O)C=C1
InChI
InChIKey=IYEWBJUCJHKLHD-UHFFFAOYSA-N
InChI=1S/C15H23N3O2.ClH/c1-4-18(5-2)11-10-16-15(20)13-6-8-14(9-7-13)17-12(3)19;/h6-9H,4-5,10-11H2,1-3H3,(H,16,20)(H,17,19);1H
Molecular Formula | ClH |
Molecular Weight | 36.461 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Molecular Formula | C15H23N3O2 |
Molecular Weight | 277.362 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Acecainide (N-acetylprocainamide), the N-acetylated metabolite of procainamide, is a Class III antiarrhythmic agent. Acecainide exerts cardiac anticholinergic effect. It elicits smooth muscle relaxation mainly through the activation of plasma membrane K+ channels. Acecainide markedly reduced premature ventricular beats and prevented induction of ventricular tachycardia. Acecainide appears to offer advantages over procainamide, particularly with respect to the reduced formation of antinuclear antibodies. Acecainide development has been discontinued.
Approval Year
PubMed
Title | Date | PubMed |
---|---|---|
N-substituted benzamides inhibit nuclear factor-kappaB and nuclear factor of activated T cells activity while inducing activator protein 1 activity in T lymphocytes. | 2001 Aug |
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Clinical review: Drug metabolism and nonrenal clearance in acute kidney injury. | 2008 |
|
Procainamide, but not N-acetylprocainamide, induces protein free radical formation on myeloperoxidase: a potential mechanism of agranulocytosis. | 2008 May |
Patents
Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 15:26:42 GMT 2023
by
admin
on
Fri Dec 15 15:26:42 GMT 2023
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Record UNII |
B9K738KX14
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Record Status |
Validated (UNII)
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Record Version |
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NCI_THESAURUS |
C47793
Created by
admin on Fri Dec 15 15:26:42 GMT 2023 , Edited by admin on Fri Dec 15 15:26:42 GMT 2023
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NCI_THESAURUS |
C93038
Created by
admin on Fri Dec 15 15:26:42 GMT 2023 , Edited by admin on Fri Dec 15 15:26:42 GMT 2023
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Code System | Code | Type | Description | ||
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B9K738KX14
Created by
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34118-92-8
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m1291
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admin on Fri Dec 15 15:26:42 GMT 2023 , Edited by admin on Fri Dec 15 15:26:42 GMT 2023
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PRIMARY | Merck Index | ||
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DTXSID1045748
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admin on Fri Dec 15 15:26:42 GMT 2023 , Edited by admin on Fri Dec 15 15:26:42 GMT 2023
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C75126
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CHEMBL1097
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759312
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71417
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251-831-2
Created by
admin on Fri Dec 15 15:26:42 GMT 2023 , Edited by admin on Fri Dec 15 15:26:42 GMT 2023
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PRIMARY |
Related Record | Type | Details | ||
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PARENT -> SALT/SOLVATE |
Related Record | Type | Details | ||
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ACTIVE MOIETY |