TETRYDAMINE MALEATE

Possibly Marketed Outside US

Details

Stereochemistry	ACHIRAL
Molecular Formula	C9H15N3.C4H4O4
Molecular Weight	281.3077
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OC(=O)\C=C/C(O)=O.CNC1=C2CCCCC2=NN1C

InChI

InChIKey=WBQNUTJPYOXRCC-BTJKTKAUSA-N

InChI=1S/C9H15N3.C4H4O4/c1-10-9-7-5-3-4-6-8(7)11-12(9)2;5-3(6)1-2-4(7)8/h10H,3-6H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1-

HIDE SMILES / InChI

Molecular Formula	C4H4O4
Molecular Weight	116.0722
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	1
Optical Activity	NONE

Molecular Formula	C9H15N3
Molecular Weight	165.2355
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/1418890 | https://www.ncbi.nlm.nih.gov/pubmed/18608303 | http://en.pharmacodia.com/web/drug/1_9558.html | https://www.ncbi.nlm.nih.gov/pubmed/1881569

Tetrydamine is a member of the indazol class of non-steroidal anti-inflammatory drugs. It is an analgesic and anti-inflammatory drug. Tetrydamine lavage reduced or eliminated all inflammation symptoms like burning, leucorrhea, etc. and resulted very well tolerated in vulvovaginitis, symptomatic bacterial vaginosis and cervicitis treatment.

Approval Year

Conditions

Condition	Modality	Highest Phase	Product
Bacterial vaginosis 10 Sources: https://www.ncbi.nlm.nih.gov/pubmed/1881569	Palliative	Approved 8429	Fomene Approved Use Unknown
Vulvovaginitis 5 Sources: https://www.ncbi.nlm.nih.gov/pubmed/1418890	Palliative	Approved 8429	Fomene Approved Use Unknown
Cervicitis 3 Sources: https://www.ncbi.nlm.nih.gov/pubmed/1418890	Palliative	Approved 8429	Fomene Approved Use Unknown

PubMed

Title	Date	PubMed

Patents

Sample Use Guides

In Vivo Use Guide

1 or 2 vaginal irrigations daily. The irrigation fluid is prepared by dissolving 500 mg of the powder formulation in one liter of water.

Route of Administration: Vaginal

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Fri Dec 15 19:12:49 GMT 2023` Edited by `admin` on `Fri Dec 15 19:12:49 GMT 2023`
Record UNII	B976EB226W
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TETRYDAMINE MALEATE

Common Name

English

Tetridamine Maleate [WHO-DD]

Common Name

English

2H-INDAZOL-3-AMINE, 4,5,6,7-TETRAHYDRO-N,2-DIMETHYL-, (2Z)-2-BUTENEDIOATE (1:1)

Systematic Name

English

TETRIDAMINE MALEATE

Common Name

English

Code System Code Type Description

CAS

22911-97-3