N-METHYLPIPERAZINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C5H12N2
Molecular Weight	100.1622
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CN1CCNCC1

InChI

InChIKey=PVOAHINGSUIXLS-UHFFFAOYSA-N

InChI=1S/C5H12N2/c1-7-4-2-6-3-5-7/h6H,2-5H2,1H3

HIDE SMILES / InChI

Molecular Formula	C5H12N2
Molecular Weight	100.1622
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Photoaddition of N-substituted piperazines to C60: an efficient approach to the synthesis of water-soluble fullerene derivatives.	2006 Jul 17	16755633
Phenothiazine molecule provides the basic chemical structure for various classes of pharmacotherapeutic agents.	2006 May-Jun	16772768
Acenaphtho[1,2-b]pyrrole derivatives as new family of intercalators: various DNA binding geometry and interesting antitumor capacity.	2006 Oct 15	16828559
Structure elucidation of a novel analogue of sildenafil detected as an adulterant in an herbal dietary supplement.	2007 Apr 11	17207601
Use of liquid chromatography-mass spectrometry and a chemical cleavage reaction for the structure elucidation of a new sildenafil analogue detected as an adulterant in an herbal dietary supplement.	2007 Aug 15	17532168
N-Methyl-piperazinediium penta-chloridoanti-monate(III) monohydrate.	2007 Dec 12	21200500
Structure determination of new analogues of vardenafil and sildenafil in dietary supplements.	2007 Feb	17364912
Synthesis of o-sulfamidotriazobenzenes from 1,1'-sulfonylbis(benzotriazole).	2007 Jul 20	17583958
Precise protein quantification based on peptide quantification using iTRAQ.	2007 Jun 21	17584939
NS-187 (INNO-406), a Bcr-Abl/Lyn dual tyrosine kinase inhibitor.	2007 Nov 14	19662183
3-(4-Methyl-piperazin-1-yl)isobenzofuran-1(3H)-one.	2008 Apr 2	21202272
Morpholine-based immonium and halogenoamidinium salts as coupling reagents in Peptide synthesis1.	2008 Apr 4	18321124
Copper(I) cyanide networks: synthesis, structure, and luminescence behavior. Part 2. Piperazine ligands and hexamethylenetetramine.	2008 Aug 4	18597424
Synthesis and Pharmacological Evaluation of (6-Substituted 4-Oxo-4H-chromene-3 yl) methyl N-substituted Aminoacetates.	2008 Jan	20390097
Use of N-methylpiperazine for the preparation of piperazine-based unsymmetrical bis-ureas as anti-HIV agents.	2008 Jul	18383064
Determination of analogs of sildenafil and vardenafil in foods by column liquid chromatography with a photodiode array detector, mass spectrometry, and nuclear magnetic resonance spectrometry.	2008 May-Jun	18567304
Refining targeted therapies in chronic myeloid leukemia: development and application of nilotinib, a step beyond imatinib.	2008 Oct 1	21127752
Improved proteome coverage by using iTRAQ labelling and peptide OFFGEL fractionation.	2008 Oct 13	18851748
Structure-activity studies on a series of a 2-aminopyrimidine-containing histamine H4 receptor ligands.	2008 Oct 23	18811133
Solution structure of a covalently bound pyrrolo[2,1-c][1,4]benzodiazepine-benzimidazole hybrid to a 10mer DNA duplex.	2009 Dec 29	19911838
Proteomics: challenges, techniques and possibilities to overcome biological sample complexity.	2009 Dec 8	20948568
Synthesis and spectral characterization of a new class of N-(N-methylpiperazinoacetyl)-2,6-diarylpiperidin-4-ones: antimicrobial, analgesic and antipyretic studies.	2009 Feb	18485539
The structure of the leukemia drug imatinib bound to human quinone reductase 2 (NQO2).	2009 Feb 24	19236722
Development and targeted use of nilotinib in chronic myeloid leukemia.	2009 Feb 6	19920910
Hoechst 33342: the dye that enabled differentiation of living X-and Y-chromosome bearing mammalian sperm.	2009 Jan 1	18952273
Structure elucidation of thioketone analogues of sildenafil detected as adulterants in herbal aphrodisiacs.	2009 Jan 15	19042103
Synthesis of some new 1,3,4-thiadiazol-2-ylmethyl-1,2,4-triazole derivatives and investigation of their antimicrobial activities.	2009 Jul	19167136
Synthesis of some new 1,2,4-triazoles, their Mannich and Schiff bases and evaluation of their antimicrobial activities.	2009 Mar	18676062
Manipulation of fluorescent and colorimetric changes of fluorescein derivatives and applications for sensing silver ions.	2009 Mar 14	19240884
Discovery of substituted N'-(2-oxoindolin-3-ylidene)benzohydrazides as new apoptosis inducers using a cell- and caspase-based HTS assay.	2009 May 15	19369076
[2-(4-Methyl-piperazin-1-ylmeth-yl)phen-yl]diphenyl-phosphane.	2009 Nov 25	21578904
Masitinib (AB1010), a potent and selective tyrosine kinase inhibitor targeting KIT.	2009 Sep 30	19789626
Synthesis and antimicrobial activities of some new 1,2,3-triazole derivatives.	2010 Apr 8	20428053
catena-Poly[(S)-2-methyl-piperazine-1,4-diium [[trichloridobismuthate(III)]-di-μ-chlorido]].	2010 Aug 11	21588498
Chalcogenides of the aminomethylphosphines derived from 1-methylpiperazine, 1-ethylpiperazine and morpholine: NMR, DFT and structural studies for determination of electronic and steric properties of the phosphines.	2010 Aug 28	20617235
Determination of individual proton affinities of ofloxacin from its UV-Vis absorption, fluorescence and charge-transfer spectra: effect of inclusion in beta-cyclodextrin on the proton affinities.	2010 Aug 5	20666527
Sulfonamide-1,2,4-thiadiazole derivatives as antifungal and antibacterial agents: synthesis, biological evaluation, lipophilicity, and conformational studies.	2010 Feb	20118573
Detection of nitric oxide in tissue samples by ESI-MS.	2010 Feb	20098762
Imatinibium dipicrate.	2010 Jan 20	21579830
Synthesis and biological evaluation of N-hydroxyphenylacrylamides and N-hydroxypyridin-2-ylacrylamides as novel histone deacetylase inhibitors.	2010 Jan 28	20017493
Crystal Structures of TbCatB and rhodesain, potential chemotherapeutic targets and major cysteine proteases of Trypanosoma brucei.	2010 Jun 8	20544024
Conjugate addition of nucleophiles to the vinyl function of 2-chloro-4-vinylpyrimidine derivatives.	2010 Mar 19	20336026
A statistics-based platform for quantitative N-terminome analysis and identification of protease cleavage products.	2010 May	20305283
Streamlined, automated protocols for the production of milligram quantities of untagged recombinant human cyclophilin-A (hCypA) and untagged human proliferating cell nuclear antigen (hPCNA) using AKTAxpress.	2010 May	19995609
[Synthesis, modifications, and antimicrobial activity of the methylpiperazinyl amides of triterpenic acids].	2010 May-Jun	20644598
Tetrasubstituted naphthalene diimide ligands with selectivity for telomeric G-quadruplexes and cancer cells.	2010 Nov 15	20932753
[Synthesis and pharmacological activity of amides and ozonolysis product of maleopimaric acid].	2010 Nov-Dec	21317950
In vitro and in vivo studies of the trypanocidal properties of WRR-483 against Trypanosoma cruzi.	2010 Sep 14	20856868
Novel tricyclic pyrazole BRAF inhibitors with imidazole or furan central scaffolds.	2010 Sep 15	20667740
Peptidyl alpha-ketoamides with nucleobases, methylpiperazine, and dimethylaminoalkyl substituents as calpain inhibitors.	2010 Sep 9	20690647

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 19:12:31 UTC 2023` Edited by `admin` on `Fri Dec 15 19:12:31 UTC 2023`
Record UNII	B92I95EL9Q
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

N-METHYLPIPERAZINE

Systematic Name

English

PIPERAZINE, 1-METHYL-

Systematic Name

English

1-METHYLPIPERAZINE

Systematic Name

English

1-METHYLPIPERAZINE [USP IMPURITY]

Common Name

English

CYCLIZINE RELATED COMPOUND A [USP-RS]

Common Name

English

NSC-30195

Code

English

NSC-30675

Code

English

1-METHYL-1,4-PIPERAZINE

Common Name

English

CYCLIZINE RELATED COMPOUND A

Common Name

English

DIETHYLCARBAMAZINE CITRATE IMPURITY A [EP IMPURITY]

Common Name

English

Code System Code Type Description

WIKIPEDIA

Methylpiperazine