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Details

Stereochemistry ACHIRAL
Molecular Formula C6H11NO
Molecular Weight 113.1576
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of N-ISOPROPYLACRYLAMIDE

SMILES

CC(C)NC(=O)C=C

InChI

InChIKey=QNILTEGFHQSKFF-UHFFFAOYSA-N
InChI=1S/C6H11NO/c1-4-6(8)7-5(2)3/h4-5H,1H2,2-3H3,(H,7,8)

HIDE SMILES / InChI

Molecular Formula C6H11NO
Molecular Weight 113.1576
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Evaluation of thermoreversible polymers containing fibroblast growth factor 9 (FGF-9) for chondrocyte culture.
2004-05-01
The effect of the processing and formulation parameters on the size of nanoparticles based on block copolymers of poly(ethylene glycol) and poly(N-isopropylacrylamide) with and without hydrolytically sensitive groups.
2004-05
Poly(N-isopropylacrylamide) copolymers for constant temperature controlled drug delivery.
2004-04-01
Local drug delivery in restenosis injury: thermoresponsive co-polymers as potential drug delivery systems.
2004-04
Temperature- and pH-responsive aminopropyl-silica ion-exchange columns grafted with copolymers of N-isopropylacrylamide.
2004-03-19
Modulation of the sensitive temperature range of fluorescent molecular thermometers based on thermoresponsive polymers.
2004-03-15
Thermoresponsive nanostructures by self-assembly of a poly(N-isopropylacrylamide)-lipid conjugate.
2004-03-03
Nematic nanotube gels.
2004-02-27
Serum-stable and long-circulating, PEGylated, pH-sensitive liposomes.
2004-02-10
Dual-stimuli-responsive hydrogels based on poly(N-isopropylacrylamide)/chitosan semi-interpenetrating networks.
2004-01-09
Temperature-responsive polymers for liquid-phase separations.
2004-01
Thermally reversible polymer gel for chondrocyte culture.
2003-12-15
Alpha,omega-functionalized poly-N-isopropylacrylamides: controlling the surface activity for vesicle adsorption by temperature.
2003-12-01
Radiation chemical studies on thermosensitive N-isopropylacrylamide and its polymer in aqueous solutions.
2003-12
Purification of histidine-tagged single-chain Fv-antibody fragments by metal chelate affinity precipitation using thermoresponsive copolymers.
2003-11-20
Novel DNA/polymer conjugate for intelligent antisense reagent with improved nuclease resistance.
2003-11-17
Complex formation of protein with different water-soluble synthetic polymers.
2003-11-11
Thermo-responsive PNiPAAm-g-PEG films for controlled cell detachment.
2003-11-11
Fluorescent molecular thermometers based on polymers showing temperature-induced phase transitions and labeled with polarity-responsive benzofurazans.
2003-11-01
Extended delivery of the antimitotic agent colchicine from thermoresponsive N-isopropylacrylamide-based copolymer films to human vascular smooth muscle cells.
2003-11-01
Monolithic valves for microfluidic chips based on thermoresponsive polymer gels.
2003-11
Transplantable urothelial cell sheets harvested noninvasively from temperature-responsive culture surfaces by reducing temperature.
2003-10
Affinity selection of target cells from cell surface displayed libraries: a novel procedure using thermo-responsive magnetic nanoparticles.
2003-10
Simple and precise preparation of a porous gel for a colorimetric glucose sensor by a templating technique.
2003-09-15
Synthesis and characterization of injectable poly(N-isopropylacrylamide-co-acrylic acid) hydrogels with proteolytically degradable cross-links.
2003-09-10
Interactions of temperature-responsive anionic polyelectrolytes with a cationic surfactant.
2003-09-01
Conjugation of penicillin acylase with the reactive copolymer of N-isopropylacrylamide: a step toward a thermosensitive industrial biocatalyst.
2003-08-02
Phase-selective solubility of poly(N-alkylacrylamide)s.
2003-07-09
Metal chelate affinity precipitation of RNA and purification of plasmid DNA.
2003-07
Thermosensitive PNIPAAm cryogel with superfast and stable oscillatory properties.
2003-06-21
Affinity thermoprecipitation and recovery of biotinylated biomolecules via a mutant streptavidin-smart polymer conjugate.
2003-05-22
Temperature-responsive cellulose by ceric(IV) ion-initiated graft copolymerization of N-isopropylacrylamide.
2003-05-14
Intramolecular complex formation of poly(N-isopropylacrylamide) with human serum albumin.
2003-05-14
Self-assembly of an environmentally responsive polymer/silica nanocomposite.
2003-05-14
Microlens formation in microgel/gold colloid composite materials via photothermal patterning.
2003-05-07
Effect of amino acid surfactants on phase transition of poly(N-isopropylacrylamide) gel.
2003-05-01
The influence of PEO/poly(vinyl phenol-co-styrene sulfonate) aqueous complex structure on flocculation.
2003-05-01
Multiple-point adsorption of terbium ions by lead ion templated thermosensitive gel: elucidating recognition of conformation in gel by terbium probe.
2003-04-30
Poly(N-isopropylacrylamide) co-polymer films as potential vehicles for delivery of an antimitotic agent to vascular smooth muscle cells.
2003-04-10
Tissue-engineered cartilage using an injectable and in situ gelable thermoresponsive gelatin: fabrication and in vitro performance.
2003-04
Preparation of comb-type N-isopropylacrylamide hydrogel beads and their application for size-selective separation media.
2003-03-11
Copolymerization of 2-carboxyisopropylacrylamide with N-isopropylacrylamide accelerates cell detachment from grafted surfaces by reducing temperature.
2003-03-11
On the characterization of pH-sensitive liposome/polymer complexes.
2003-03-11
Detection by circular dichroism of conformational transitions in pH and thermosensitive copolymers based on N-isopropylacrylamide and N-methacryloyl-L-leucine.
2003-03
Accelerated cell sheet recovery by co-grafting of PEG with PIPAAm onto porous cell culture membranes.
2003-03
Surfactant induced drug delivery based on the use of thermosensitive polymers.
2003-02-14
Mri measurements of T1, T2 and D for gels undergoing volume phase transition.
2003-02
Affinity precipitation separation of DNA binding protein using block conjugate composed of poly(N-isopropylacrylamide) grafted double-stranded DNA and double-stranded DNA containing a target sequence.
2002-12
Phenotype of hepatocyte spheroids in Arg-GLY-Asp (RGD) containing a thermo-reversible extracellular matrix.
2002-07
Functional regulation of biomolecule using DNA-conjugation.
2002
Patents
Substance Class Chemical
Created
by admin
on Mon Mar 31 18:57:00 GMT 2025
Edited
by admin
on Mon Mar 31 18:57:00 GMT 2025
Record UNII
B7GFF17L9U
Record Status Validated (UNII)
Record Version
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Name Type Language
N-ISOPROPYLACRYLAMIDE
HSDB  
Systematic Name English
NSC-11448
Preferred Name English
2-PROPENAMIDE, N-(1-METHYLETHYL)-
Systematic Name English
N-ISOPROPYL ACRYLAMIDE
Systematic Name English
N-(1-METHYLETHYL)-2-PROPENAMIDE
Systematic Name English
N-ISOPROPYLACRYLAMIDE [HSDB]
Common Name English
ISOPROPYLACRYLAMIDE
Systematic Name English
N-ISOPROPYLPROPENAMIDE
Systematic Name English
ACRYLAMIDE, N-ISOPROPYL-
Systematic Name English
Code System Code Type Description
HSDB
5868
Created by admin on Mon Mar 31 18:57:00 GMT 2025 , Edited by admin on Mon Mar 31 18:57:00 GMT 2025
PRIMARY
PUBCHEM
16637
Created by admin on Mon Mar 31 18:57:00 GMT 2025 , Edited by admin on Mon Mar 31 18:57:00 GMT 2025
PRIMARY
CAS
2210-25-5
Created by admin on Mon Mar 31 18:57:00 GMT 2025 , Edited by admin on Mon Mar 31 18:57:00 GMT 2025
PRIMARY
ECHA (EC/EINECS)
218-638-5
Created by admin on Mon Mar 31 18:57:00 GMT 2025 , Edited by admin on Mon Mar 31 18:57:00 GMT 2025
PRIMARY
MESH
C067295
Created by admin on Mon Mar 31 18:57:00 GMT 2025 , Edited by admin on Mon Mar 31 18:57:00 GMT 2025
PRIMARY
NSC
11448
Created by admin on Mon Mar 31 18:57:00 GMT 2025 , Edited by admin on Mon Mar 31 18:57:00 GMT 2025
PRIMARY
EPA CompTox
DTXSID0033754
Created by admin on Mon Mar 31 18:57:00 GMT 2025 , Edited by admin on Mon Mar 31 18:57:00 GMT 2025
PRIMARY
FDA UNII
B7GFF17L9U
Created by admin on Mon Mar 31 18:57:00 GMT 2025 , Edited by admin on Mon Mar 31 18:57:00 GMT 2025
PRIMARY