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Details

Stereochemistry ACHIRAL
Molecular Formula C2H3O3.Na
Molecular Weight 98.0332
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SODIUM GLYCOLATE

SMILES

[Na+].OCC([O-])=O

InChI

InChIKey=VILMUCRZVVVJCA-UHFFFAOYSA-M
InChI=1S/C2H4O3.Na/c3-1-2(4)5;/h3H,1H2,(H,4,5);/q;+1/p-1

HIDE SMILES / InChI

Molecular Formula Na
Molecular Weight 22.98976928
Charge 1
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C2H3O3
Molecular Weight 75.0434
Charge -1
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

SODIUM GLYCOLATE, a sodium salt of carboxymethyl ether, is used as a pharmaceutical grade dissolution excipient for solid dosage forms. It absorbs water rapidly, resulting in swelling which leads to the rapid disintegration of tablets and capsules. Without a disintegrant, these may not dissolve appropriately and may effect the amount of active ingredient absorbed, thereby decreasing effectiveness.

Approval Year

Conditions

ConditionModalityTargetsHighest PhaseProduct
Preventing
CLEAR CELL SALICYLIC CLARIFYING TONIC

PubMed

Substance Class Chemical
Record UNII
B75E535IMI
Record Status Validated (UNII)
Record Version