Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C2H3O3.Na |
| Molecular Weight | 98.0332 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[Na+].OCC([O-])=O
InChI
InChIKey=VILMUCRZVVVJCA-UHFFFAOYSA-M
InChI=1S/C2H4O3.Na/c3-1-2(4)5;/h3H,1H2,(H,4,5);/q;+1/p-1
| Molecular Formula | C2H3O3 |
| Molecular Weight | 75.0434 |
| Charge | -1 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | Na |
| Molecular Weight | 22.9898 |
| Charge | 1 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
SODIUM GLYCOLATE, a sodium salt of carboxymethyl ether, is used as a pharmaceutical grade dissolution excipient for solid dosage forms. It absorbs water rapidly, resulting in swelling which leads to the rapid disintegration of tablets and capsules. Without a disintegrant, these may not dissolve appropriately and may effect the amount of active ingredient absorbed, thereby decreasing effectiveness.
Approval Year
Conditions
| Condition | Modality | Targets | Highest Phase | Product |
|---|---|---|---|---|
| Preventing | CLEAR CELL SALICYLIC CLARIFYING TONIC Approved UsePrevention and treatment of Acne and acne-prone skin. A salicylic/glycolic acid skin clarifying removes excess surface oil. A blend of anti-oxidants leaves skin fresh and shine-free. Launch Date1.26230397E12 |
PubMed
| Title | Date | PubMed |
|---|---|---|
| Intravenous nedaplatin and intraarterial cisplatin with transcatheter arterial embolization for patients with locally advanced uterine cervical cancer. | 2001 |
|
| Molecular biology of the plastidic phosphorylated serine biosynthetic pathway in Arabidopsis thaliana. | 2001 |
|
| Combinatory anti-tumor effects of electroporation-mediated chemotherapy and wild-type p53 gene transfer to human esophageal cancer cells. | 2001 Apr |
|
| Perturbation of rat renal tubule transport of the organic cation amantadine in recent onset streptozotocin-induced diabetes and in uninephrectomy. | 2001 Jan |
|
| Synthesis of the left-hand portion of geldanamycin using an anti glycolate aldol reaction. | 2001 Jan 25 |
|
| [Concurrent chemoradiation therapy with nedaplatin for high-risk cervical cancer--clinical investigation of adverse events]. | 2001 Jul |
|
| Transcriptional and posttranscriptional regulation of the glycolate oxidase gene in tobacco seedlings. | 2001 Mar |
|
| Biochemical characterization of the 2-ketoacid reductases encoded by ycdW and yiaE genes in Escherichia coli. | 2001 Mar 15 |
|
| An aldol approach to the synthesis of the EF fragment of spongistatin 1. | 2001 Mar 22 |
|
| Glycolic acid treatment increases type I collagen mRNA and hyaluronic acid content of human skin. | 2001 May |
|
| [Small cell carcinoma of the urinary bladder: a case report]. | 2001 Oct |
|
| Current and future potential roles of the platinum drugs in the treatment of ovarian cancer. | 2001 Sep |
|
| Identification of a set of genes involved in the formation of the substrate for the incorporation of the unusual "glycolate" chain extension unit in ansamitocin biosynthesis. | 2002 Apr 24 |
|
| [A case of advanced esophageal cancer with multiple lymph node metastases successfully treated with induction chemotherapy consisting of nedaplatin and 5-FU followed by chemoradiotherapy]. | 2002 Aug |
|
| Potential mechanisms of marked hyperoxaluria not due to primary hyperoxaluria I or II. | 2002 Aug |
|
| Phase I study of combination chemotherapy with 5-fluorouracil (5-FU) and nedaplatin (NDP): adverse effects and eecommended dose of NDP administered after 5-FU. | 2002 Dec |
|
| Insights into substrate binding and catalytic mechanism of human tyrosyl-DNA phosphodiesterase (Tdp1) from vanadate and tungstate-inhibited structures. | 2002 Dec 13 |
|
| Drought and oxidative load in the leaves of C3 plants: a predominant role for photorespiration? | 2002 Jun |
|
| Purification and characterization of malate synthase from the glucose-grown wood-rotting basidiomycete Fomitopsis palustris. | 2002 Mar |
|
| Synthesis of a novel class of polyhydroxyalkanoates in Arabidopsis peroxisomes, and their use in monitoring short-chain-length intermediates of beta-oxidation. | 2002 May |
|
| Sensitive and real-time determination of H2O2 release from intact peroxisomes. | 2002 May 1 |
|
| "Inverse sodium hydride": a crystalline salt that contains H(+) and Na(-). | 2002 May 29 |
|
| [Combination chemotherapy of paclitaxel followed by nedaplatin for human ovarian cancer]. | 2002 Nov |
|
| Genetic analysis--a diagnostic tool for primary hyperoxaluria type I. | 2002 Nov |
|
| The combined effect of drought stress and heat shock on gene expression in tobacco. | 2002 Nov |
|
| Irinotecan plus cisplatin has substantial antitumor effect as salvage chemotherapy against germ cell tumors. | 2002 Nov 1 |
|
| Carbon exchange in hot alkaline degradation of glucose. | 2002 Nov 29 |
|
| Powder compaction properties of sodium starch glycolate disintegrants. | 2002 Sep |
|
| Evaluation of the effect of triterpenes on urinary risk factors of stone formation in pyridoxine deficient hyperoxaluric rats. | 2002 Sep |
|
| Influence of excipients, drugs, and osmotic agent in the inner core on the time-controlled disintegration of compression-coated ethylcellulose tablets. | 2002 Sep |
|
| Repeated arthralgia associated with granulocyte colony stimulating factor administration. | 2002 Sep |
|
| Irinotecan in patients with relapsed or cisplatin-refractory germ cell cancer: a phase II study of the German Testicular Cancer Study Group. | 2002 Sep 23 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Wed Jul 05 23:24:10 UTC 2023
by
admin
on
Wed Jul 05 23:24:10 UTC 2023
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| Record UNII |
B75E535IMI
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| Record Status |
Validated (UNII)
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| Record Version |
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| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
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NCI_THESAURUS |
C78284
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EPA PESTICIDE CODE |
103
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C031149
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1356762
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DTXSID6047153
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220-624-9
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517347
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B75E535IMI
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100000129315
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2836-32-0
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B75E535IMI
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C84158
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SUB38237
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| Related Record | Type | Details | ||
|---|---|---|---|---|
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PARENT -> SALT/SOLVATE |
