Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C2H3O3.Na |
| Molecular Weight | 98.0332 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[Na+].OCC([O-])=O
InChI
InChIKey=VILMUCRZVVVJCA-UHFFFAOYSA-M
InChI=1S/C2H4O3.Na/c3-1-2(4)5;/h3H,1H2,(H,4,5);/q;+1/p-1
| Molecular Formula | C2H3O3 |
| Molecular Weight | 75.0434 |
| Charge | -1 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | Na |
| Molecular Weight | 22.9898 |
| Charge | 1 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
SODIUM GLYCOLATE, a sodium salt of carboxymethyl ether, is used as a pharmaceutical grade dissolution excipient for solid dosage forms. It absorbs water rapidly, resulting in swelling which leads to the rapid disintegration of tablets and capsules. Without a disintegrant, these may not dissolve appropriately and may effect the amount of active ingredient absorbed, thereby decreasing effectiveness.
Approval Year
Conditions
| Condition | Modality | Targets | Highest Phase | Product |
|---|---|---|---|---|
| Preventing | CLEAR CELL SALICYLIC CLARIFYING TONIC Approved UsePrevention and treatment of Acne and acne-prone skin. A salicylic/glycolic acid skin clarifying removes excess surface oil. A blend of anti-oxidants leaves skin fresh and shine-free. Launch Date2009 |
PubMed
| Title | Date | PubMed |
|---|---|---|
| Ethylene glycol toxicity: the role of serum glycolic acid in hemodialysis. | 2001 |
|
| The integration of paclitaxel and new platinum compounds in the treatment of advanced ovarian cancer. | 2001 |
|
| Evaluation of the functional equivalence of crospovidone NF from different sources. I. Physical characterization. | 2001 |
|
| Cytocidal effect and DNA damage of nedaplatin in vitro by simulating pharmacokinetic parameters. | 2001 Apr |
|
| The gene yghK linked to the glc operon of Escherichia coli encodes a permease for glycolate that is structurally and functionally similar to L-lactate permease. | 2001 Apr |
|
| Combinatory anti-tumor effects of electroporation-mediated chemotherapy and wild-type p53 gene transfer to human esophageal cancer cells. | 2001 Apr |
|
| Iron coordination in photosystem II: interaction between bicarbonate and the QB pocket studied by Fourier transform infrared spectroscopy. | 2001 Apr 3 |
|
| [Evaluation of a combination chemotherapy with nedaplatin and 5-FU for oral cancers]. | 2001 Aug |
|
| Ethylene glycol-mediated tubular injury: identification of critical metabolites and injury pathways. | 2001 Aug |
|
| Structure of an active soluble mutant of the membrane-associated (S)-mandelate dehydrogenase. | 2001 Aug 21 |
|
| Synthesis of the left-hand portion of geldanamycin using an anti glycolate aldol reaction. | 2001 Jan 25 |
|
| [Concurrent chemoradiation therapy with nedaplatin for high-risk cervical cancer--clinical investigation of adverse events]. | 2001 Jul |
|
| [Targetting intra-arterial infusion chemotherapy with nedaplatin for oral cancer]. | 2001 Jul |
|
| [A case of esophageal carcinoma with multiple liver metastases successfully treated with nedaplatin (NDP) and 5-fluorouracil (5-FU) combined with radiotherapy]. | 2001 Jun |
|
| Reversal of cisplatin resistance by the 1,4-benzothiazepine derivative, JTV-519. | 2001 Jun |
|
| Biodegradable microspheres of novel segmented poly(ether-ester-amide)s based on poly(epsilon-caprolactone) for the delivery of bioactive compounds. | 2001 Jun |
|
| Cytocidal effect and DNA damage of nedaplatin: a mathematical model and analysis of experimental data. | 2001 Mar |
|
| [Concurrent chemoradiotherapy for advanced cervical cancer--a pilot study]. | 2001 Mar |
|
| Local structure analysis of Ti species stabilized in ion exchangeable layer solids by x-ray absorption spectroscopy. | 2001 Mar 1 |
|
| Surface modification of polyhydroxyalkanoate films and their interaction with human fibroblasts. | 2001 Mar 14 |
|
| Plant tissue-based chemiluminescence flow biosensor for glycolic acid. | 2001 Mar 15 |
|
| Biochemical characterization of the 2-ketoacid reductases encoded by ycdW and yiaE genes in Escherichia coli. | 2001 Mar 15 |
|
| An aldol approach to the synthesis of the EF fragment of spongistatin 1. | 2001 Mar 22 |
|
| Glycolic acid treatment increases type I collagen mRNA and hyaluronic acid content of human skin. | 2001 May |
|
| Peroxisomal targeting of mammalian hydroxyacid oxidase 1 requires the C-terminal tripeptide SKI. | 2001 May |
|
| AGXT gene mutations and their influence on clinical heterogeneity of type 1 primary hyperoxaluria. | 2001 Oct |
|
| Sequence-dependent antitumor efficacy of combination chemotherapy with nedaplatin, a newly developed platinum, and paclitaxel. | 2001 Oct 22 |
|
| [Effect of combination chemotherapy with nedaplatin and 5-FU for head and neck squamous cell carcinoma]. | 2001 Sep |
|
| The catalytic role of tyrosine 254 in flavocytochrome b2 (L-lactate dehydrogenase from baker's yeast). Comparison between the Y254F and Y254L mutant proteins. | 2001 Sep |
|
| A dynamic study and modeling of the formation of polyhydroxyalkanoates combined with treatment of high strength wastewater. | 2001 Sep 1 |
|
| Small cell lung cancer: defining a role for emerging platinum drugs. | 2002 |
|
| Global expression profiling of acetate-grown Escherichia coli. | 2002 Apr 12 |
|
| [A case of advanced esophageal cancer with multiple lymph node metastases successfully treated with induction chemotherapy consisting of nedaplatin and 5-FU followed by chemoradiotherapy]. | 2002 Aug |
|
| [Current and future state of chemoradiotherapy for head and neck cancer]. | 2002 Feb |
|
| Transport of L-Lactate, D-Lactate, and glycolate by the LldP and GlcA membrane carriers of Escherichia coli. | 2002 Jan 18 |
|
| Proteomic analysis of leaf peroxisomal proteins in greening cotyledons of Arabidopsis thaliana. | 2002 Jul |
|
| Epithelial ovarian cancer: second and third line chemotherapy (review). | 2002 Jul |
|
| Structure of the complex of heptakis(2,6-di-O-methyl)-beta-cyclodextrin with (2,4-dichlorophenoxy)acetic acid. | 2002 Jul 16 |
|
| Conversion of phosphoglycolate to phosphate termini on 3' overhangs of DNA double strand breaks by the human tyrosyl-DNA phosphodiesterase hTdp1. | 2002 Jul 26 |
|
| Primary hyperoxaluria: a rare but important cause of nephrolithiasis. | 2002 Jun |
|
| Particular aspects of platinum compounds used at present in cancer treatment. | 2002 Jun |
|
| Chemical characterisation of sodium starch glycolate particles. | 2002 Jun 20 |
|
| Sensitive and real-time determination of H2O2 release from intact peroxisomes. | 2002 May 1 |
|
| "Inverse sodium hydride": a crystalline salt that contains H(+) and Na(-). | 2002 May 29 |
|
| [Combination chemotherapy of paclitaxel followed by nedaplatin for human ovarian cancer]. | 2002 Nov |
|
| Carbon exchange in hot alkaline degradation of glucose. | 2002 Nov 29 |
|
| Total synthesis of (+)-geldanamycin and (-)-o-quinogeldanamycin with use of asymmetric anti- and syn-glycolate aldol reactions. | 2002 Oct 3 |
|
| Powder compaction properties of sodium starch glycolate disintegrants. | 2002 Sep |
|
| Evaluation of the effect of triterpenes on urinary risk factors of stone formation in pyridoxine deficient hyperoxaluric rats. | 2002 Sep |
|
| Repeated arthralgia associated with granulocyte colony stimulating factor administration. | 2002 Sep |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 15:55:53 GMT 2023
by
admin
on
Fri Dec 15 15:55:53 GMT 2023
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| Record UNII |
B75E535IMI
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| Record Status |
Validated (UNII)
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| Record Version |
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NCI_THESAURUS |
C78284
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EPA PESTICIDE CODE |
103
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C031149
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1356762
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DTXSID6047153
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220-624-9
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517347
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B75E535IMI
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100000129315
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2836-32-0
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B75E535IMI
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C84158
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SUB38237
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| Related Record | Type | Details | ||
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PARENT -> SALT/SOLVATE |
