Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C2H3O3.Na |
| Molecular Weight | 98.0332 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[Na+].OCC([O-])=O
InChI
InChIKey=VILMUCRZVVVJCA-UHFFFAOYSA-M
InChI=1S/C2H4O3.Na/c3-1-2(4)5;/h3H,1H2,(H,4,5);/q;+1/p-1
| Molecular Formula | C2H3O3 |
| Molecular Weight | 75.0434 |
| Charge | -1 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | Na |
| Molecular Weight | 22.9898 |
| Charge | 1 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
SODIUM GLYCOLATE, a sodium salt of carboxymethyl ether, is used as a pharmaceutical grade dissolution excipient for solid dosage forms. It absorbs water rapidly, resulting in swelling which leads to the rapid disintegration of tablets and capsules. Without a disintegrant, these may not dissolve appropriately and may effect the amount of active ingredient absorbed, thereby decreasing effectiveness.
Approval Year
Conditions
| Condition | Modality | Targets | Highest Phase | Product |
|---|---|---|---|---|
| Preventing | CLEAR CELL SALICYLIC CLARIFYING TONIC Approved UsePrevention and treatment of Acne and acne-prone skin. A salicylic/glycolic acid skin clarifying removes excess surface oil. A blend of anti-oxidants leaves skin fresh and shine-free. Launch Date1.26230397E12 |
PubMed
| Title | Date | PubMed |
|---|---|---|
| Intravenous nedaplatin and intraarterial cisplatin with transcatheter arterial embolization for patients with locally advanced uterine cervical cancer. | 2001 |
|
| The integration of paclitaxel and new platinum compounds in the treatment of advanced ovarian cancer. | 2001 |
|
| The gene yghK linked to the glc operon of Escherichia coli encodes a permease for glycolate that is structurally and functionally similar to L-lactate permease. | 2001 Apr |
|
| Iron coordination in photosystem II: interaction between bicarbonate and the QB pocket studied by Fourier transform infrared spectroscopy. | 2001 Apr 3 |
|
| [Evaluation of a combination chemotherapy with nedaplatin and 5-FU for oral cancers]. | 2001 Aug |
|
| Structure of an active soluble mutant of the membrane-associated (S)-mandelate dehydrogenase. | 2001 Aug 21 |
|
| Preclinical in vivo antitumor efficacy of nedaplatin with gemcitabine against human lung cancer. | 2001 Jan |
|
| Cytocidal effect and DNA damage of nedaplatin: a mathematical model and analysis of experimental data. | 2001 Mar |
|
| Local structure analysis of Ti species stabilized in ion exchangeable layer solids by x-ray absorption spectroscopy. | 2001 Mar 1 |
|
| Plant tissue-based chemiluminescence flow biosensor for glycolic acid. | 2001 Mar 15 |
|
| An aldol approach to the synthesis of the EF fragment of spongistatin 1. | 2001 Mar 22 |
|
| [Platinum compounds in cancer therapy--past, present, and future]. | 2001 May |
|
| Peroxisomal targeting of mammalian hydroxyacid oxidase 1 requires the C-terminal tripeptide SKI. | 2001 May |
|
| The catalytic role of tyrosine 254 in flavocytochrome b2 (L-lactate dehydrogenase from baker's yeast). Comparison between the Y254F and Y254L mutant proteins. | 2001 Sep |
|
| Effect of pharmacotechnical design on the in vitro interaction of ketoconazole tablets with non-systemic antacids. | 2001 Sep 11 |
|
| Multiple sources of sodium starch glycolate, NF: evaluation of functional equivalence and development of standard performance tests. | 2002 |
|
| Action of carriers on Carbamazepine dissolution. | 2002 |
|
| Fast- and slow-release tablets for oral administration of flavonoids: rutin and quercetin. | 2002 Apr |
|
| [A case of advanced esophageal cancer with multiple lymph node metastases successfully treated with induction chemotherapy consisting of nedaplatin and 5-FU followed by chemoradiotherapy]. | 2002 Aug |
|
| Preclinical combination chemotherapy of nedaplatin with gemcitabine against gemcitabine-refractory human lung cancer. | 2002 Aug 8 |
|
| Insights into substrate binding and catalytic mechanism of human tyrosyl-DNA phosphodiesterase (Tdp1) from vanadate and tungstate-inhibited structures. | 2002 Dec 13 |
|
| [Current and future state of chemoradiotherapy for head and neck cancer]. | 2002 Feb |
|
| [Cloning and expression of spinach glycolate oxidase in Escherichia coli]. | 2002 Jan |
|
| An aldol-based approach to the synthesis of the antibiotic anisomycin. | 2002 Jan 24 |
|
| Proteomic analysis of leaf peroxisomal proteins in greening cotyledons of Arabidopsis thaliana. | 2002 Jul |
|
| Epithelial ovarian cancer: second and third line chemotherapy (review). | 2002 Jul |
|
| Structure of the complex of heptakis(2,6-di-O-methyl)-beta-cyclodextrin with (2,4-dichlorophenoxy)acetic acid. | 2002 Jul 16 |
|
| Conversion of phosphoglycolate to phosphate termini on 3' overhangs of DNA double strand breaks by the human tyrosyl-DNA phosphodiesterase hTdp1. | 2002 Jul 26 |
|
| Oxygen exchange in relation to carbon assimilation in water-stressed leaves during photosynthesis. | 2002 Jun |
|
| Chemical characterisation of sodium starch glycolate particles. | 2002 Jun 20 |
|
| Purification and characterization of malate synthase from the glucose-grown wood-rotting basidiomycete Fomitopsis palustris. | 2002 Mar |
|
| An inherited metabolic disorder presenting as ethylene glycol intoxication in a young adult. | 2002 Mar |
|
| [Combined preoperative therapy for oral cancer with nedaplatin and radiation]. | 2002 Mar |
|
| [Combination chemotherapy with nedaplatin (CDGP) and 5-FU for oral cancer]. | 2002 Mar |
|
| Synthesis of a novel class of polyhydroxyalkanoates in Arabidopsis peroxisomes, and their use in monitoring short-chain-length intermediates of beta-oxidation. | 2002 May |
|
| Sensitive and real-time determination of H2O2 release from intact peroxisomes. | 2002 May 1 |
|
| Asymmetric total synthesis of (-)-laulimalide: exploiting the asymmetric glycolate alkylation reaction. | 2002 May 29 |
|
| "Inverse sodium hydride": a crystalline salt that contains H(+) and Na(-). | 2002 May 29 |
|
| [Combination chemotherapy of paclitaxel followed by nedaplatin for human ovarian cancer]. | 2002 Nov |
|
| Metabolic shifts in hypersaline microbial mats upon addition of organic substrates. | 2002 Nov |
|
| Genetic analysis--a diagnostic tool for primary hyperoxaluria type I. | 2002 Nov |
|
| Carbon exchange in hot alkaline degradation of glucose. | 2002 Nov 29 |
|
| Influence of excipients, drugs, and osmotic agent in the inner core on the time-controlled disintegration of compression-coated ethylcellulose tablets. | 2002 Sep |
|
| A formula for predicting optimal dosage of nedaplatin based on renal function in adult cancer patients. | 2002 Sep |
|
| Repeated arthralgia associated with granulocyte colony stimulating factor administration. | 2002 Sep |
|
| Irinotecan in patients with relapsed or cisplatin-refractory germ cell cancer: a phase II study of the German Testicular Cancer Study Group. | 2002 Sep 23 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 16 18:40:27 UTC 2022
by
admin
on
Fri Dec 16 18:40:27 UTC 2022
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| Record UNII |
B75E535IMI
|
| Record Status |
Validated (UNII)
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| Record Version |
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-
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Common Name | English |
| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
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NCI_THESAURUS |
C78284
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EPA PESTICIDE CODE |
103
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C031149
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1356762
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DTXSID6047153
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220-624-9
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517347
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B75E535IMI
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2836-32-0
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B75E535IMI
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C84158
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SUB38237
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| Related Record | Type | Details | ||
|---|---|---|---|---|
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PARENT -> SALT/SOLVATE |
