XANTHOANTHRAFIL

COC1=CC=C(CNC(=O)C2=CC(=CC=C2NC(C)CO)[N+]([O-])=O)C=C1OC

InChIKey=ZISFCTXLAXIEMV-UHFFFAOYSA-N

InChI=1S/C19H23N3O6/c1-12(11-23)21-16-6-5-14(22(25)26)9-15(16)19(24)20-10-13-4-7-17(27-2)18(8-13)28-3/h4-9,12,21,23H,10-11H2,1-3H3,(H,20,24)

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

PubMed

Title	Date	PubMed
Determination of (R)-xanthoanthrafil, a phosphodiesterase-5 inhibitor, in a dietary supplement promoted for sexual enhancement.	2008-02	18239316
Phosphodiesterase type 5 inhibition ameliorates nephrotoxicity induced by cyclosporin A in spontaneous hypertensive rats.	2003-09-12	14519421
FR226807: a potent and selective phosphodiesterase type 5 inhibitor.	2001-10-05	11675048

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 21:37:04 GMT 2025` Edited by `admin` on `Mon Mar 31 21:37:04 GMT 2025`
Record UNII	B6ZMZ878RF
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

(±)-XANTHOANTHRAFIL

Preferred Name

English

XANTHOANTHRAFIL

Common Name

English

BENZAMIDE, N-((3,4-DIMETHOXYPHENYL)METHYL)-2-((2-HYDROXY-1-METHYLETHYL)AMINO)-5-NITRO-

Systematic Name

English

BENZAMIDENAFIL

Common Name

English

Code System Code Type Description

PUBCHEM

10110873