Details
Stereochemistry | ACHIRAL |
Molecular Formula | C23H24FNO4 |
Molecular Weight | 397.4394 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
COC1(CCOCC1)C2=CC(OCC3=CC4=C(C=C3)N(C)C(=O)C=C4)=CC(F)=C2
InChI
InChIKey=SLZBEPLWGGRZAY-UHFFFAOYSA-N
InChI=1S/C23H24FNO4/c1-25-21-5-3-16(11-17(21)4-6-22(25)26)15-29-20-13-18(12-19(24)14-20)23(27-2)7-9-28-10-8-23/h3-6,11-14H,7-10,15H2,1-2H3
Molecular Formula | C23H24FNO4 |
Molecular Weight | 397.4394 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Approval Year
PubMed
Title | Date | PubMed |
---|---|---|
Calcium ionophore (A-23187) induced peritoneal eicosanoid biosynthesis: a rapid method to evaluate inhibitors of arachidonic acid metabolism in vivo. | 1993 |
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The 5-lipoxygenase inhibitors ZD2138 and ZM230487 are potent and selective inhibitors of several antigen-induced guinea-pig pulmonary responses. | 1994 May 23 |
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Characterization of the arachidonate and ATP binding sites of human 5-lipoxygenase using photoaffinity labeling and enzyme immobilization. | 1995 Oct 17 |
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Inhibition of 5-lipoxygenase diminishes neurally evoked tachykinergic contraction of guinea pig isolated airway. | 1998 May |
|
Induction of hepatic microsomal drug-metabolizing enzymes by inhibitors of 5-lipoxygenase (5-LO): studies in rats and 5-LO knockout mice. | 2001 Sep |
Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 15:44:10 GMT 2023
by
admin
on
Fri Dec 15 15:44:10 GMT 2023
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Record UNII |
B6G6OX1ZH5
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Record Status |
Validated (UNII)
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Record Version |
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DTXSID90161477
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B6G6OX1ZH5
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132306
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admin on Fri Dec 15 15:44:10 GMT 2023 , Edited by admin on Fri Dec 15 15:44:10 GMT 2023
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