GITOFORMATE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C46H64O19
Molecular Weight	920.989
Optical Activity	UNSPECIFIED
Defined Stereocenters	21 / 21
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[H][C@]12CC[C@]3([H])[C@]([H])(CC[C@]4(C)[C@H]([C@H](C[C@]34O)OC=O)C5=CC(=O)OC5)[C@@]1(C)CC[C@@H](C2)O[C@H]6C[C@H](OC=O)[C@H](O[C@H]7C[C@H](OC=O)[C@H](O[C@H]8C[C@H](OC=O)[C@H](OC=O)[C@@H](C)O8)[C@@H](C)O7)[C@@H](C)O6

InChI

InChIKey=DOMHWKQEPDYUQX-LJAQBGIBSA-N

InChI=1S/C46H64O19/c1-24-41(59-23-51)32(55-19-47)14-38(60-24)64-43-26(3)62-39(16-34(43)57-21-49)65-42-25(2)61-37(15-33(42)56-20-48)63-29-8-10-44(4)28(13-29)6-7-31-30(44)9-11-45(5)40(27-12-36(52)54-18-27)35(58-22-50)17-46(31,45)53/h12,19-26,28-35,37-43,53H,6-11,13-18H2,1-5H3/t24-,25-,26-,28-,29+,30+,31-,32+,33+,34+,35+,37+,38+,39+,40+,41-,42-,43-,44+,45-,46+/m1/s1

HIDE SMILES / InChI

Molecular Formula	C46H64O19
Molecular Weight	920.989
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	21 / 21
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/6687204 | https://www.ncbi.nlm.nih.gov/pubmed/6541927

Gitoformate (or pentaformylgitoxin), a kidney independent glycoside, was used in patients with atrial fibrillation and in the treatment of congestive heart failure. Information, that this drug is used now is not available.

Approval Year

PubMed

Title	Date	PubMed
[Circadian aspects of heart rate in patients with atrial fibrillation: comparative influence of digoxin and pentaformylgitoxin].	1983 Dec	6687204

Substance Class	Chemical Created by `admin` on `Fri Dec 15 18:25:39 GMT 2023` Edited by `admin` on `Fri Dec 15 18:25:39 GMT 2023`
Record UNII	B69U29O7J9
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

GITOFORMATE

Official Name

English

AC-2770

Code

English

FORMILOXINE

Common Name

English

GITOXIN 3',3'',3''',4''',16-PENTAFORMATE

Common Name

English

AC 2770

Code

English

PENTAFORMYLGITOXIN

Common Name

English

GITOXIN, PENTAFORMATE

Common Name

English

Gitoformate [WHO-DD]

Common Name

English

GITOFORMATE [MART.]

Common Name

English

FORMILOXIN

Common Name

English

gitoformate [INN]

Common Name

English

Classification Tree Code System Code

WHO-VATC

QC01AA09