U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 13:39:02 GMT 2023
Edited
by admin
on Sat Dec 16 13:39:02 GMT 2023
Protein Type ENZYME
Protein Sub Type
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
B5QXZ49C7Y
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
AMINE OXIDASE (FLAVIN-CONTAINING) A
Common Name English
MONOAMINE OXIDASE A (HUMAN GENE MAOA)
Common Name English
MONOAMINE OXIDASE TYPE A
Common Name English
MAO-A
Common Name English
MAOA
Common Name English
Code System Code Type Description
CAS
479852-35-2
Created by admin on Sat Dec 16 13:39:03 GMT 2023 , Edited by admin on Sat Dec 16 13:39:03 GMT 2023
ALTERNATIVE
WIKIPEDIA
MONOAMINE OXIDASE
Created by admin on Sat Dec 16 13:39:03 GMT 2023 , Edited by admin on Sat Dec 16 13:39:03 GMT 2023
PRIMARY
CAS
624651-39-4
Created by admin on Sat Dec 16 13:39:03 GMT 2023 , Edited by admin on Sat Dec 16 13:39:03 GMT 2023
ALTERNATIVE
CAS
481302-91-4
Created by admin on Sat Dec 16 13:39:03 GMT 2023 , Edited by admin on Sat Dec 16 13:39:03 GMT 2023
ALTERNATIVE
CAS
391962-32-6
Created by admin on Sat Dec 16 13:39:03 GMT 2023 , Edited by admin on Sat Dec 16 13:39:03 GMT 2023
PRIMARY
CAS
480770-54-5
Created by admin on Sat Dec 16 13:39:03 GMT 2023 , Edited by admin on Sat Dec 16 13:39:03 GMT 2023
ALTERNATIVE
FDA UNII
B5QXZ49C7Y
Created by admin on Sat Dec 16 13:39:03 GMT 2023 , Edited by admin on Sat Dec 16 13:39:03 GMT 2023
PRIMARY
UNIPROT
P21397
Created by admin on Sat Dec 16 13:39:03 GMT 2023 , Edited by admin on Sat Dec 16 13:39:03 GMT 2023
PRIMARY
EC (ENZYME CLASS)
EC 1.4.3.4
Created by admin on Sat Dec 16 13:39:03 GMT 2023 , Edited by admin on Sat Dec 16 13:39:03 GMT 2023
PRIMARY
Related Record Type Details
INHIBITOR -> METABOLIC ENZYME
SUBSTRATE -> METABOLIC ENZYME
SUBSTRATE -> METABOLIC ENZYME
SUBSTRATE -> METABOLIC ENZYME
MAJOR
INHIBITOR -> TARGET
INHIBITOR -> TARGET
SUBSTRATE->ENZYME
INHIBITOR -> TARGET
INHIBITOR -> METABOLIC ENZYME
INHIBITOR -> TARGET
SUBSTRATE -> METABOLIC ENZYME
INHIBITOR -> METABOLIC ENZYME
IC50
SUBSTRATE -> METABOLIC ENZYME
INHIBITOR -> TARGET
SUBSTRATE -> METABOLIC ENZYME
INHIBITOR -> TARGET
Strong inhibitor. As can be seen, 5-FMT dose-dependently inhibited only the activity of MAO A similarly in these regions of the brain with no effect on MAOB. The IC50 values (the dose to inhibit MAO A activity 50%) in these regions of the brain were about 11 mg/kg (0.05 mmol/kg).
RADIOLIGAND->TARGET
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER AVERAGE(CALCULATED) CHEMICAL