Details
Stereochemistry | RACEMIC |
Molecular Formula | C29H38N2O4.2ClH |
Molecular Weight | 551.545 |
Optical Activity | ( + / - ) |
Defined Stereocenters | 2 / 2 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
Cl.Cl.[H][C@@]12CC(C[C@H]3NCCC4=CC(OC)=C(OC)C=C34)=C(CC)CN1CCC5=CC(OC)=C(OC)C=C25
InChI
InChIKey=WNJZDNXVVDNPSI-FJEGXLQFSA-N
InChI=1S/C29H38N2O4.2ClH/c1-6-18-17-31-10-8-20-14-27(33-3)29(35-5)16-23(20)25(31)12-21(18)11-24-22-15-28(34-4)26(32-2)13-19(22)7-9-30-24;;/h13-16,24-25,30H,6-12,17H2,1-5H3;2*1H/t24-,25+;;/m1../s1
Molecular Formula | C29H38N2O4 |
Molecular Weight | 478.623 |
Charge | 0 |
Count |
|
Stereochemistry | RACEMIC |
Additional Stereochemistry | No |
Defined Stereocenters | 2 / 2 |
E/Z Centers | 0 |
Optical Activity | UNSPECIFIED |
Molecular Formula | ClH |
Molecular Weight | 36.461 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Oral dehydroemetine dihydrochloride (+/-) (Mebadin) was found useful both as a tissue and contact amoebicide. It is much less toxic and more active than emetine and can be given in larger doses and for longer periods with safety. Owing to the quick excretion, repeat courses can be given at short intervals, as necessary, without danger. No serious side effects were noted particularly with the oral form and it was far better tolerated by children, who received relatively higher dosage than most adults. The only contra-indication is for patients with manifest decompensation of vital organs, or fevers. Mebadin injection and Mebadin tablets are discontinued products.
Approval Year
Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 07:11:42 GMT 2023
by
admin
on
Sat Dec 16 07:11:42 GMT 2023
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Record UNII |
B4O7C9XKP1
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Record Status |
Validated (UNII)
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Record Version |
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-
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Code System | Code | Type | Description | ||
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14358-43-1
Created by
admin on Sat Dec 16 07:11:42 GMT 2023 , Edited by admin on Sat Dec 16 07:11:42 GMT 2023
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m4144
Created by
admin on Sat Dec 16 07:11:42 GMT 2023 , Edited by admin on Sat Dec 16 07:11:42 GMT 2023
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PRIMARY | Merck Index | ||
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DTXSID60162471
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admin on Sat Dec 16 07:11:42 GMT 2023 , Edited by admin on Sat Dec 16 07:11:42 GMT 2023
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B4O7C9XKP1
Created by
admin on Sat Dec 16 07:11:42 GMT 2023 , Edited by admin on Sat Dec 16 07:11:42 GMT 2023
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21124735
Created by
admin on Sat Dec 16 07:11:42 GMT 2023 , Edited by admin on Sat Dec 16 07:11:42 GMT 2023
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149634
Created by
admin on Sat Dec 16 07:11:42 GMT 2023 , Edited by admin on Sat Dec 16 07:11:42 GMT 2023
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